H O W T O R E A D D N A ? 

H E L A C E L L S ( W H Y H E L A ? ) 

H E L A C E L L S It is the oldest and most commonly used human cell line. It was derived from cervical cancer cells taken on February 8, 1951, from Henrietta Lacks, a patient who eventually died of her cancer on October 4, 1951. 

Let us assume you managed to extract the DNA from HELA cells D N A 

D N A S 

D N A I S V E RY L O N G 

D N A S O U P 

T H E N E W S PA P E R P R O B L E M 

T H E N E W S PA P E R P R O B L E M 

B A C K T O B I O L O G Y ? Bioinformatics Bioinformatics Biology Biology Biology 

O V E R L A P P I N G I S E A S Y (if the sequence is known) 

O V E R L A P P I N G I S H A R D (if the sequence is unknown) Find a path in the de Bruijn graph that visits every edge exactly once - Eulerian path 

W H AT I S T H E FA S T E S T M A M M A L ? 

S O , W H AT D I D J U N E 2 7 , 2 0 0 0 N Y T I M E S S AY ? 

S O , W H AT D I D J U N E 2 7 , 2 0 0 0 N Y T I M E S S AY ? 

T H A N K Y O U ! Presentation is based on materials from https://www.coursera.org/course/bioinformatics