Bioconductor 3.12 Leonardo Collado Torres lcolladotor.github.io 2020-11-20

LIEBER INSTITUTE for BRAIN DEVELOPMENT http://bioconductor.org/about/

LIEBER INSTITUTE for BRAIN DEVELOPMENT http://bioconductor.org/news/bioc_3_12_release/

LIEBER INSTITUTE for BRAIN DEVELOPMENT https://twitter.com/mikelove/status/1324348808327794689?s=20

LIEBER INSTITUTE for BRAIN DEVELOPMENT https://twitter.com/LIBDrstats/status/1324861604488503300?s=20

LIEBER INSTITUTE for BRAIN DEVELOPMENT New packages I was involved in biocthis: R package development megadepth: faster coverage summaries over genomic regions for BigWig / BAM files; with David Zhang (UCL) & Christopher Wilks + Ben Langmead (JHU CS) recount3: 750,000+ public human/mouse RNA-seq dasper: interpreting exon-exon junctions in the clinic; David Zhang & Mina Ryten (UCL)

LIEBER INSTITUTE for BRAIN DEVELOPMENT Highlighted by Mike Love (subset) bambu: multi-sample transcript discovery and quantification using long read RNA-Seq data pipeComp: facilitate the comparison of pipelines involving various steps and parameters recountmethylation: similar to recount2 but for methylation data; Sean Maden & Abhinav Nellore velociraptor: Bioconductor-friendly wrappers for RNA velocity calculations in single-cell RNA-seq data

LIEBER INSTITUTE for BRAIN DEVELOPMENT Highlighted in the LIBD rstats club (subset) BayesSpace: clustering method for Visium data (discussed in our spatial journal club) DegNorm: base-pair coverage normalization of RNA-seq data (presentation by Josh Stolz https://www.youtube.com/watch?v=YF5jw--Ky-g ) Nebulosa: visualization method for dense clustered data (tSNE/UMAP; LIBD rstats club today) famat: create shiny (interactive) visualizations for gene pathways, GO terms and more SpatialExperiment: for storing Visium data (we are involved in planning updates for it)

LIEBER INSTITUTE for BRAIN DEVELOPMENT https://www.youtube.com/c/LeonardoColladoTorres/playlists

LIEBER INSTITUTE for BRAIN DEVELOPMENT How I’m trying to keep myself updated ● LIBD rstats club: Fridays 1pm, open to LIBD & collaborators https://groups.google.com/g/libd-rstats-club + upload to YouTube https://www.youtube.com/c/LeonardoColladoTorres/playlists ● Leo’s team meeting (closed; Wednesdays 3pm): we record our journal/software club portion and upload to YouTube ● Spatial journal club (closed; bi-weekly on Thursdays 11 am): no recordings