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!CBTI$ ܧଓత3VCZ.VTDMF.JYJO࣮ફೖ໳ େߐށ3VCZձٞ/JOKB5BMLT IUUQTQIPUPTHPPHMFDPNTIBSF"'2JQ0NZK.#XD:3Q"+:RO,57;O,S32NYDH7/N,0;%G'@3+%ME.8U.*N;.;(EHQIPUP"'2JQ197'"@Q*5EpI@:4''1C'8V36$,8@[T LFZ0867LQG3&Y,2O+F8;,;5/VB[L6IIC'/Y2CZLPZIPHF

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SVCZLBJHJFGGFDU

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IUUQTCBTIDP⒏DJBMGBOCPYDDQPTUT

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IUUQTCBTIDP⒏DJBMGBOCPYDDQPTUT

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IUUQTCBTIDP⒏DJBMGBOCPYDDQPTUT

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IUUQTXXXGBOCPYDDUBHT3VCZ.VTDMF.JYJO IUUQTUXJUUFSDPNTFBSDI R3VCZ.VTDMF.JYJOTSDUZQFE@RVFSZGMJWF

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IUUQTYDPNCBTI$TUBUVT IUUQTCBTIDP⒏DJBMGBOCPYDDQPTUT

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ܧଓత3VCZ.VTDMF.JYJO࣮ફೖ໳ େߐށ3VCZձٞ/JOKB5BMLT !CBTI$

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!CBTI$͜͠͹͹ͬ͠Ύ IUUQTCBTIDP⒏DJBMGBOCPYDD w ·͡Ίͳ4&ݱ৬ϐΫγϒ ג ೥બख w ޿ࠂ഑৴ΤϯδχΞˠ։ൃϚωʔδϟʔ ˠؔ࿈ձࣾ$50ˠ71P&ˠࣾ಺*5෦໳্ཱͪ͛ ˠܦӦاըิࠤ w ٕज़৬ԣஅ૊৫ΤϯδχΞΪϧυ্ཱͪ͛

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Θͨ͠ͷ 3VCZ.VTDMF.JYJO࣮૷

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͔ͭͯԿ౓΋܁Γฦ͖ͯ͠·ͨ͠ɻ δϜܖ໿ͯ͠࠷ॳ͸೤৺ʹߦ͘ɻ ͦͷ͏ͪߦ͔ͳ͘ͳΔɻ ৺ػҰసͱ͹͔Γʹ·ͨߦ͕͘ɺ ͙͢ʹ·ͨߦ͔ͳ͘ͳΔɻ

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ΤϯδχΞϦϯάͰղܾ͢Δ ࠜੑɺ͕Μ͹Γɺͦ͏͍͏ͷφγͰ

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΢ΟʔΫϦʔϧʔςΟʔϯ ೥͔Βͪ͜Βɻ·ͩ೥ɻ w ΢ΣΠττϨʔχϯά w ि෦Ґ෼ׂ w ճ͋ͨΓ͙࣌ؒΒ͍ w Ϩετσʔ w ि w ௕ڑ཭ࢄาʹ౰ͯΔ͜ͱ΋͋Δ

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ΤϯδχΞϦϯάͷ ΩʔϙΠϯτ఺

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ᶃܹࢗΛےણҡʹೖΕΔ͜ͱ -PBE

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ᶄ಴࠳͠ͳ͍͜ͱ "WBJMBCJMJUZ

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ʮτϨʔχϯάͷ̏ͭͷݪཧͱ̑ͭͷݪଇʯ IUUQTZVOPNBSVDJUZUPNJOBHBOPKQUSBJOJOH@JOGPU

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ʮτϨʔχϯάͷ̏ͭͷݪཧͱ̑ͭͷݪଇʯ ͭͷݪཧ w ϩʔυ͔͚ΔͱޮՌ͕ͰΔ w ΍ͬͨͱ͜ΖʹޮՌ͕ͰΔ w ΍ΊͨΒݩͷ໦Ѩ໻

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ʮτϨʔχϯάͷ̏ͭͷݪཧͱ̑ͭͷݪଇʯ ͭͷݪଇ w ৭ʑ૊Έ߹ΘͤΑ͏ w ݸਓ͝ͱʹΧελϜ͠Α͏ w ҙࣝΛ޲͚Α͏ w ઴ਐతʹ͔͠৳ͼͳ͍Α w ܁Γฦ͠େࣄ

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Θͨ͠ͷ3VCZ.VTDMF.JYJOͷ࣮૷ ΤϯδχΞϦϯάͷΩʔϙΠϯτ w -PBE w ܹࢗΛےણҡʹೖΕΔ͜ͱ w "WBJMBCJMJUZ w ಴࠳͠ͳ͍͜ͱ

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ᶃܹࢗΛےણҡʹೖΕΔ͜ͱ -PBE

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֤෦ҐʹܹࢗΛೖΕ͍ͯ͘ ͔͠΋઴ਐతʹڧ͍ܹࢗΛ IUUQTZVOPNBSVDJUZUPNJOBHBOPKQUSBJOJOH@JOGPU

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શ਎Λ෼ׂͯ͠೔෦Ґʹूத ʮࠓ೔͸˔˔ͷ೔ʯํࣜͷϧʔςΟʔϯͰόϥϯεऔΓ w ϧʔςΟʔϯߏ੒ w ڳɺഎதɺݞɺ٭ɺ࿹ɺٳଉɺٳଉ w ʮ෼ׂʯ w Θͨ͠ͷϨϕϧͰ͸෼͚͔͗͢΋͠Εͳ͍ w Ͱ΋γϯϓϧͰ໎͏ͱ͜Ζ͕গͳͯ͘ଓ͚΍͍͢

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୯ҐɿLH -PBEॏྔYճ਺

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-PBEͷ͔͚ํ Ͱ͖Δ͚ͩॏ͍΋ͷΛͨ͘͞Μͷճ਺΍Δ w छ໨ɿdηοτ w ηοτؒٳଉɿd෼͙Β͍ w ηοτ͋ͨΓճ਺ɿʙճͷϨϯδͰݻఆ w ॏྔઃఆɿճ਺Ϩϯδ಺Ͱલճ௒͑Λ໨ࢦ͢ w ૯ηοτ਺ͦͷ೔͔ͭ͑Δ࣌ؒͷݶΓ w ͱݴ͍͍ͨͱ͜Ζ͕ͩɺ͍͍͙ͩͨ࣌ؒΒ͍

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ͭ·Γɺ࠷େͷม਺͸ॏྔઃఆ

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ॏྔઃఆΛ୳Δํ๏ ه࿥͸͋Δ͚Ͳɺମௐ΍ػछʹΑͬͯมΘΔ w ճ਺Ϩϯδ಺Ͱʮ͜ΕҎ্͸ΉΉΉΓΓΓΓΓΓΓΓ́ʯʹ͖ͨΒ׬ྃ w όΠφϦʔαʔν w ΤΠϠʔͰηοτͯ͠ɺ͍͚ΔΉΓͰ୳Δ w ͱ͸͍͑͜͜·Ͱख୳Γ͸ͦ͏ͳ͍ w ϦχΞαʔν w ηοτ͝ͱʹॏྔΛ૿΍͢ w ΢ΥʔϜΞοϓʹ΋ͳͬͯศར

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ΤϯδχΞϦϯάͷ ΩʔϙΠϯτ఺

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ᶄ಴࠳͠ͳ͍͜ͱ "WBJMBCJMJUZ

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ܧଓେࣄͱ͍͑Δ ೉͍͔͠Βͦ͜Θ͟Θ͟ॻ͍ͯ͋Δ IUUQTZVOPNBSVDJUZUPNJOBHBOPKQUSBJOJOH@JOGPU

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࢝ΊΒΕͯ΋ଓ͚ΒΕͳ͍ͷ͕ਓੜ $FTUMBWJFͰ͢Α w ௨͍΋͠ͳ͍δϜ݄ձඅΛ෷͍ଓ͚ΔΤϯυ w ౎౓෷͍ʹͨͬͯ͠ߦ͖΋͠ͳ͍ w ύʔιφϧ͸༧໿ͱΔͷ͕໘౗ʹͳͬͯ͠·͏ w ͍͔ʹଓ͔ͤΔ͔ɺ཭୤͔͔͠ΔલʹϦςϯγϣϯ͔͚Δ͔͕উෛ w ήʔϜ΍ࣄۀͱҰॹ

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.5#'ͱ.553 "WBJMBCJMJUZͷݹయతࢦඪ w .5#'ɿ w .FBO5JNF#FUXFFO'BJMVSF w ฏۉނোִؒ w .553ɿ w .FBO5JNF5P3FDPWFSZ w ฏۉ෮چ଴ͪ࣌ؒ

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.5#'ͱ.553 "WBJMBCJMJUZͷݹయతࢦඪ w .5#'ɿ w .FBO5JNF#FUXFFO'BJMVSF w ฏۉނোִؒ w .553ɿ w .FBO5JNF5P3FDPWFSZ w ฏۉ෮چ଴ͪ࣌ؒ Ξϯίϯτʔϥϒϧ ڐ༰͢Δ ͪ͜Βʹ஫ྗ͢Δ

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.5#'ͱ.553 "WBJMBCJMJUZͷݹయతࢦඪ w .5#'ɿ w .FBO5JNF#FUXFFO'BJMVSF w ฏۉނোִؒ w .553ɿ w .FBO5JNF5P3FDPWFSZ w ฏۉ෮چ଴ͪ࣌ؒ ͍ΖΜͳࣄ৘Ͱ τϨʔχϯάͰ͖ͳ͍೔͸ෆճආ ɾࠓ೔͸ମௐ͕Α͘ͳ͍ ɾ࢓ࣄ͕๩͍͠ ɾಓ۩Λ๨Εͨ ʮࠓ೔͚ͩٳ΋͏ʯ͕ɺ ߃ৗతͳٳΈʹͳΒͳ͍Α͏ʹ͢Δ

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ʮࠓ೔͚ͩٳ΋͏ʯ͕߃ৗతͳٳΈʹͭͳ͕Δ࠷େཁҼ ೳಈతʹʮߦ͘ʯ ൑அίετ͸ੌ͍

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ೳಈతʹʮߦ͘ʯ൑அίετ͸ੌ͍ͳΒ͹ ߦ͘൑அΛ͠ͳ͚Ε͹͍͍

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͔Βͩͭ͘Γ͸ຖ೔ͷ΋ͷ ٯʹɺٳଉ೔ແ͠Ͱ͸μϝ͕͋Δ w ࡢ೔͸ʮٳΉʯͱ͍͏͔Βͩͭ͘ΓΛ͠·ͨ͠Ͷ w ࠓ೔͸ࠓ೔ͷ͔Βͩͭ͘ΓΛ͠·͠ΐ͏ w ϧʔςΟʔϯʹ͍ͦͬͯͭ΋௨ΓΛ฻Β͢ w ຖ೔ͷ͜ͱΛຖ೔ͷΑ͏ʹ΍Δ w Ϟνϕ͕͡Όͳ͍ɻʮͩͬͯ࢓ࣄͰ͠ΐʯ

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͋Θͤͯຎࡲ΋ݮΒͦ͏

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ຎࡲ಴࠳Λਖ਼౰Խ͢Δཧ۶ͷ༨஍ ͍ͱ΋ͨ΍͘͢ਓྨ͸಴࠳͢ΔͷͰͦͷՄೳੑ͸Լ͍͛ͨ w ৔ॴબͼ w ߦ͖΍͔ͯͭ͘͢ܧଓͯ͠ࢧ෷͑Δ৔ॴͷબఆ w Ṍ͚ۚΛੵΈଓ͚Δͱ଍ൈ͚Ͱ͖ͳ͘ͳΔ w ܧଓͷ͝๙ඒ w ຖճͷܹࢗͷྔ͚ͩͰ͸͝๙ඒʹ͸଍Γͳ͍ w ใुܥΛܹࢗͯ͠μϧ͍ͷʹճΛॏͳΔΑ͏ʹ͢Δ

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৔ॴબͼ ߴֹա͗͸͠ΜͲ͍͕ίετΛ͔͚ଓ͚ͯ߱ΓΒΕͳ͘͢Δ খֹ ߴֹ Πχγϟϧ ϥϯχϯά ύʔιφϧ ࣗ୐δϜԽ άϧʔϓύʔιφϧ ແਓδϜ ༗ਓͷδϜ ެӦࢪઃ ࣗ୐Ͱࣗॏ

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ܧଓͷ͝๙ඒήʔϜੑ ࣗ෼͚ͩͰ׬݁Ͱ͖Δͨͷ͍͠ιϩϓϨΠͷΤϯλʔςΠϯϝϯτ w ଞऀͱίϛϡχέʔγϣϯ͕ෆཁ w ࢓ࣄͰ͓ͳ͔͍ͬͺ͍ύʔςΟʔϓϨΠ͸΍ͬͯ·͢ w ϨϕϧΞοϓͷ͏Ε͠͞ w ࠷େͷ-PBEΛߋ৽Ͱ͖Δͱ͏Ε͍͠ϥϯμϜใु w ຖ݄ͷτϨʔχϯάͨ͠೔਺ΛͨΊΔ w ϥδΦମૢͷελϯϓํࣜɻ࿈ଓϩάΠϯ͸్੾ΕΔͱݏ͔ͩΒݟͳ͍

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۩ମతͳ͓͢͢Ί࣮૷

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݁࿦͔Β͍͏ͱ ͱΓ͋͑ͣΰʔϧυδϜΛΦεεϝ w τϨʔφʔ͖ͭνϡʔτϦΞϧ w श׳Խࠜ෇͘ظؒͱϘϦϡʔϜ w ϩάΠϯϘʔφε΋͋Δ w τϨʔφʔͷઆಘྗ͕ڧ͍ w ٬૚͕Α͍ w ૯ͯࣗ͡෼͚ͩʹ޲͖߹͍ͬͯΔ

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ଞͷબ୒ࢶ΋͍͍΋ͷͰ͢ ·ͣ͸౿Έग़͠΍͍͢΋ͷ͔Βଓ͔͘ͳΛࢼ͢ͷ΋͍͍ w ࣗ୐Ͱࣗॏ w ࣗ෼Ͱଓ͚ΒΕΔͷͳΒ΋ͬͱ΋͓͕͔͔ۚΒͳ͍ w ެӦͷδϜ w Ϧʔζφϒϧ͕͞ϋʔυϧͷ௿͞ͱͯ͠͸͡Ί΍͍͢ w ແਓδϜ w ௨͍ଓ͚ΒΕΔ͔ͱɺ͓ళͷ٬૚࣍ୈͱ͸ࢥ͏ w ύʔιφϧτϨʔχϯά w ͍͍τϨʔφʔʹग़ձ͑ͨͳΒ͹ଓ͚΍ͯ͘͢ޮՌͷظ଴౓΋ߴ͍

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ࣗ෼ͰϩάΠϯϘʔφεΛ༻ҙ ۩ମతʹ͸ʮϥδΦମૢͷελϯϓʯϝιου w ه࿥Λ௥Ճ͢Δ͚ͩͰ˔͕͍ͭͯ͏Ε͍͠ w ͞Βʹ࠷େ-PBEߋ৽Λڭ͑ͯ͘ΕΔͷ͸͏Ε͍͠ w

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ϧʔςΟʔϯ ೔෦Ґ͸γϯϓϧʹऔΓ૊Έ΍͍͢ w શ਎·Μ΂Μͳ͘Λϝχϡʔʹ͢Δͷ͸֮͑Δෛՙ͕ߴ͍ w ೔෦ҐͰ͋Ε͹ஔ͍ͯ͋Δͦͷ෦Ґ༻ϚγϯΛͱʹ͔͘࢖͑͹ऴΘΔ w ڳɺഎதɺݞɺ٭ɺ࿹

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෦ҐͷதͰҰճͰ΋΍ͬͨΒʮͰ͖ͨʯѻ͍ θϩΠν͡Όͳ͍ɺͪΐͬͱͰ΋΍ͬͨΒมԽ͕ى͖Δ w ຖ೔ɺ΍Γ͸͡ΊΔͱ͖͕͍ͪ͹Μ͔ͬͨΔ͍ w Ͱ΋΍Γ͸͡ΊͨΒ࡞ۀڵฃ͕ੜ͡Δ w τʔλϧͷϩʔυߋ৽͸ϋΠείΞͷ໘ന͞

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ࢀߟࢿྉ ͍ͣΕ΋,JOEMFͰಡΉ͜ͱ͕Ͱ͖·͢

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ܧଓత3VCZ.VTDMF.JYJO࣮ફೖ໳ େߐށ3VCZձٞ/JOKB5BMLT !CBTI$ IUUQTQIPUPTHPPHMFDPNTIBSF"'2JQ0NZK.#XD:3Q"+:RO,57;O,S32NYDH7/N,0;%G'@3+%ME.8U.*N;.;(EHQIPUP"'2JQ197'"@Q*5EpI@:4''1C'8V36$,8@[T LFZ0867LQG3&Y,2O+F8;,;5/VB[L6IIC'/Y2CZLPZIPHF