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Data-driven innovation [email protected] Dr. Matt Wood @mza

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Hello

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Hello

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Data

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DNA

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Chromosome 11 : ACTN3 : rs1815739

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Chromosome X : rs6625163

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Chromosome 19 : FUT2 : rs601338

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Chromosome 2 : rs10427255

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TYPE II Chromosome 10 : rs7903146

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+0.25 Chromosome 15 : rs2472297

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I know this, because...

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A T C G G T C C A G G

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A T C G G T C C A G G A G C C A G G U C C Transcription

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A T C G G T C C A G G A G C C A G G U C C Translation Ser Glu Val Transcription

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Chromosome 11 : ACTN3 : rs1815739

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Chromosome X : rs6625163

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Chromosome 19 : FUT2 : rs601338

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Chromosome 2 : rs10427255

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TYPE II Chromosome 10 : rs7903146

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+0.25 Chromosome 15 : rs2472297

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I know all that, because...

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Human Genome Project

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40 species ensembl.org

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Compare

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Change

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Less

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Compare

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Transformative

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Data generation costs are falling everywhere

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Customer segmentation, financial modeling, system analysis, line of sight, business intelligence.

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Opportunity

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Transformation

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Innovation

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Generation Collection & storage Analytics & computation Collaboration & sharing

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Generation Collection & storage Analytics & computation Collaboration & sharing lower cost, increased throughput

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Generation Collection & storage Analytics & computation Collaboration & sharing lower cost, increased throughput highly constrained

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Barrier

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Data generation challenge X

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Analytics challenge

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Accessibility challenge

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Enter the AWS Cloud

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Utility

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Remove constraints

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Data-driven innovation

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Distributed

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2

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2 Software for distributed storage & analysis

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2 Software for distributed storage & analysis Infrastructure for distributed storage & analysis

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Software Frameworks for data-intensive work loads. Distributed by design.

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Infrastructure Platform for data-intensive work loads. Distributed by design.

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Support the data timeline

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Generation Collection & storage Analytics & computation Collaboration & sharing highly constrained

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Generation Collection & storage Analytics & computation Collaboration & sharing

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Lower the barrier to entry

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Agility

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Responsive

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Generation Collection & storage Analytics & computation Collaboration & sharing

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Generation DynamoDB Analytics & computation Collaboration & sharing

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Generation DynamoDB EC2, Elastic MapReduce Collaboration & sharing

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Generation DynamoDB EC2, Elastic MapReduce S3, Public Datasets

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Tools and techniques for working productively with data

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Scale

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Secure

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2 Software for distributed storage & analysis Infrastructure for distributed storage & analysis

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Amazon EC2

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Scale out systems Embarrassingly parallel Queue based distribution Small, medium and high scale

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High performance

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High performance Compute performance

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Cluster Compute Intel Xeon E5-2670 10 gigabit, non-blocking network 60.5 Gb Placement groupings

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Cluster Compute Intel Xeon E5-2670 10 gigabit, non-blocking network 60.5 Gb Placement groupings +GPU

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240 TFLOPS

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High performance Compute performance IO performance

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Unstructured

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Variable

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Amazon DynamoDB Predictable, consistent performance Unlimited storage Single digit millisecond latencies No schema. Zero admin.

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...and SSDs for all

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hi1.4xlarge 2 x 1Tb SSD storage 10 gigabit networking HVM: 90k IOPS read, 9k to 75k write PV: 120k IOPS read, 10k to 85k write

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Netflix “The hi1.4xlarge configuration is about half the system cost for the same throughput.” http://techblog.netflix.com/2012/07/benchmarking-high-performance-io-with.html

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Provisioned IOPS Provision required IO performance EBS optimized instances

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Cost optimization

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Reserved capacity

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Reserved capacity On-demand

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Reserved capacity On-demand

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Spot instances

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$0.2530 vs $2.40

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2 Software for distributed storage & analysis Infrastructure for distributed storage & analysis

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map/reduce

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Map. Reduce.

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Write functions. Scale up.

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Hadoop

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Undi erentiated heavy lifting

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Amazon Elastic MapReduce Managed Hadoop Clusters Easy to provision and monitor Write two functions. Scale up. Choice of Hadoop flavors

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Amazon Elastic MapReduce Integrates with S3 Analytics for DynamoDB Perfect for Spot pricing

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Input data S3

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Elastic MapReduce Code Input data S3

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Elastic MapReduce Code Name node Input data S3

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Elastic MapReduce Code Name node Input data S3 Elastic cluster

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Elastic MapReduce Code Name node Input data S3 Elastic cluster HDFS

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Elastic MapReduce Code Name node Input data S3 Elastic cluster HDFS Queries + BI Via JDBC, Pig, Hive

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Elastic MapReduce Code Name node Output S3 + SimpleDB Input data S3 Elastic cluster HDFS Queries + BI Via JDBC, Pig, Hive

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Output S3 + SimpleDB Input data S3

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CDC Centers for Disease Control and Prevention

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“BioSense 2.0 protects the health of the American people by providing timely insight into the health of communities, regions, and the nation by o ering a variety of features to improve data collection, standardization, storage, analysis, and collaboration”

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Health data Collection & storage Analytics & computation Collaboration & sharing

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Health data Collection & storage Analytics & computation Collaboration & sharing highly constrained

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HIPAA, HITECH, FISMA Moderate

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GovCloud

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Beyond a definition of Big Data

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Chromosome 11 : ACTN3 : rs1815739

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Chromosome X : rs6625163

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Chromosome 19 : FUT2 : rs601338

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Chromosome 2 : rs10427255

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TYPE II Chromosome 10 : rs7903146

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+0.25 Chromosome 15 : rs2472297

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Thank you aws.amazon.com @mza [email protected]