Slide 14
Slide 14 text
14
バイオマーカーとしてのエピゲノムの活用
疾患の有無や
健康状態・精神状態
の判別
1. “An epigenome-wide DNA methylation study
of PTSD and depression in World Trade
Center responders.”,2017,”TranslPsychiatry”,’
2. “An epigenome-wide methylation study of
healthy individuals with or without depressive
symptoms.",2018,"J Hum Genet"
3. "Epigenetic profiles associated with major
depression in the human
brain.",2017,"Psychiatry Res“
4. "Epigenetic outlier profiles in depression: A
genome-wide DNA methylation analysis of
monozygotic twins.",2018,"PLoS One"
(例)DNAのメチル化とうつ病の相関性を示す論文
エピゲノムを見ることで、健康状態や精神状態のリスクを評価できる