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౦େපӃ์ࣹઢՊϨδσϯτηϛφʔ ҩྍݴޠॲཧ͜ͱ͸͡Ί ʙ͜ͱ͹ͷ"*ͰԿ͕Ͱ͖Δʁʙ  ౦ژେֶେֶӃҩֶܥݚڀՊ ੜମ෺ཧҩֶઐ߈ % தଜ ༏ଠ

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தଜ ༏ଠ :VUB/BLBNVSB     ʙ  ʙ ࣗݾ঺հ ๺ւಓࡳຈࢢ ੜ·Ε ๺ྮߴ౳ֶߍ ଔۀ ౦ژେֶҩֶ෦ҩֶՊ ଔۀ ์ࣹઢՊઐ໳ҩ औಘ ౦େපӃ์ࣹઢՊ ΠϝʔδϥϘ *$"- େֶӃੜ ݚڀςʔϚࣗવݴޠॲཧͷը૾਍அ΁ͷԠ༻ ಸྑઌ୺Պֶٕज़େֶӃେֶ /"*45 ιʔγϟϧɾίϯϐϡʔςΟϯάݚڀࣨ ࠃ಺ཹֶ /-1एखͷձγϯϙδ΢Ϝ ӡӦҕһ

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ҩྍݴޠॲཧͱ͸ʁ ҩྍݴޠॲཧ #JPNFEJDBMOBUVSBMMBOHVBHFQSPDFTTJOH • ࣗવݴޠॲཧΛҩྍʹԠ༻͢Δ͜ͱ ࣗવݴޠॲཧ /BUVSBMMBOHVBHFQSPDFTTJOH /-1 • ࣗવݴޠΛίϯϐϡʔλͰॲཧ͢Δ͜ͱ ͜ͱ͹ͷ"* ࣗવݴޠ /BUVSBMMBOHVBHF • ਓ͕ؒҙࢥૄ௨ʹ࢖͏ࣗવൃੜతͳݴޠ ೔ຊޠ ӳޠ ʜ ਓ޻ݴޠ "SUJGJDJBMMBOHVBHF • ਓҝతʹ࡞ΒΕͨݴޠ Τεϖϥϯτ ίϯϐϡʔλݴޠ ʜ ٕज़తʹ͸ ΄΅ಉ͡

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͖͔͚ͬ ͳͥ์ࣹઢՊҩͳͷʹݴޠΛʁ ˡ ిࢠΧϧς΍ಡӨϨϙʔτͰͷݕࡧ͠ʹ͕͖͔͚ͬ͘͞ $07*% ✅ $07*%ͱͯ͠యܕత ❌ $07*%͸൱ఆత ؊ࡉ๔؞ ✅ 4 4ଟൃ؊ࡉ๔؞͍ٙ ❌ ؊ࡉ๔؞ज़ޙɿ࠶ൃΛೝΊ·ͤΜ ❌ ଟൃ)$$ज़લ ˡ ِཅੑ $07*%Ͱ͸ͳ͍ ˡ ِӄੑ ݺশΏΕ͕͋Δͱर͑ͳ͍ ˡ ِཅੑ ͢Ͱʹ࣏ྍޙ ݕࡧػೳɼͲͷ͘Β͍࢖͍ͬͯ·͔͢ʁ ʢ͋·Γຖ೔͘͢͝པ͍ͬͯΔํ͸͍ͳ͍ͷͰ͸ʣ

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͓͠ͳ͕͖ 01 ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠ 02 ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ 03 ͜ͱ͹ͷ"*Λ΋ͬͱҩྍʹ׆͔ͨ͢Ίʹ͸

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͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠ 2017 BERT J Devlin et al. Google LLC. 2014 word2vec T Mikolov et al. Google LLC. 2017 Transformer A Vaswani et al. Google Brain 2019 T5 C Raffel et al. Google LLC. 1990's〜 େྔσʔλ ͔Βͷֶश ʙ1980's ਓ͕ؒஞҰ ϧʔϧΛ ॻ͖Լ͢ 2016 ౦ϩϘ͘Μ ϓϩδΣΫτ ऴྃ 2018 GPT A Radford et al. Open AI 2021 DALL-E A Ramesh et al. Open AI ɾౙͷ࣌୅͸աڈͷ΋ͷ

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2017 BERT J Devlin et al. Google LLC. 2014 word2vec T Mikolov et al. Google LLC. 2017 Transformer A Vaswani et al. Google Brain 2019 T5 C Raffel et al. Google LLC. 1990's〜 େྔσʔλ ͔Βͷֶश ʙ1980's ਓ͕ؒஞҰ ϧʔϧΛ ॻ͖Լ͢ 2016 ౦ϩϘ͘Μ ϓϩδΣΫτ ऴྃ 2018 GPT A Radford et al. Open AI 2021 DALL-E A Ramesh et al. Open AI ɾౙͷ࣌୅͸աڈͷ΋ͷ IUUQTEJBNPOEKQBSUJDMFT ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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2017 BERT J Devlin et al. Google LLC. 2014 word2vec T Mikolov et al. Google LLC. 2017 Transformer A Vaswani et al. Google Brain 2019 T5 C Raffel et al. Google LLC. 1990's〜 େྔσʔλ ͔Βͷֶश ʙ1980's ਓ͕ؒஞҰ ϧʔϧΛ ॻ͖Լ͢ 2016 ౦ϩϘ͘Μ ϓϩδΣΫτ ऴྃ 2018 GPT A Radford et al. Open AI 2021 DALL-E A Ramesh et al. Open AI ɾౙͷ࣌୅͸աڈͷ΋ͷ ɾ೥͔ΒจॻಡղείΞ͸ਓؒҎ্ IUUQTEJBNPOEKQBSUJDMFT ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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2017 BERT J Devlin et al. Google LLC. 2014 word2vec T Mikolov et al. Google LLC. 2017 Transformer A Vaswani et al. Google Brain 2019 T5 C Raffel et al. Google LLC. 1990's〜 େྔσʔλ ͔Βͷֶश ʙ1980's ਓ͕ؒஞҰ ϧʔϧΛ ॻ͖Լ͢ 2016 ౦ϩϘ͘Μ ϓϩδΣΫτ ऴྃ 2018 GPT A Radford et al. Open AI 2021 DALL-E A Ramesh et al. Open AI ɾౙͷ࣌୅͸աڈͷ΋ͷ ɾ೥͔ΒจॻಡղείΞ͸ਓؒҎ্ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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2017 BERT J Devlin et al. Google LLC. 2014 word2vec T Mikolov et al. Google LLC. 2017 Transformer A Vaswani et al. Google Brain 2019 T5 C Raffel et al. Google LLC. 1990's〜 େྔσʔλ ͔Βͷֶश ʙ1980's ਓ͕ؒஞҰ ϧʔϧΛ ॻ͖Լ͢ 2016 ౦ϩϘ͘Μ ϓϩδΣΫτ ऴྃ 2018 GPT A Radford et al. Open AI 2021 DALL-E A Ramesh et al. Open AI ɾౙͷ࣌୅͸աڈͷ΋ͷ ɾ೥͔ΒจॻಡղείΞ͸ਓؒҎ্ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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2017 BERT J Devlin et al. Google LLC. 2014 word2vec T Mikolov et al. Google LLC. 2017 Transformer A Vaswani et al. Google Brain 2019 T5 C Raffel et al. Google LLC. 1990's〜 େྔσʔλ ͔Βͷֶश ʙ1980's ਓ͕ؒஞҰ ϧʔϧΛ ॻ͖Լ͢ 2016 ౦ϩϘ͘Μ ϓϩδΣΫτ ऴྃ 2018 GPT A Radford et al. Open AI 2021 DALL-E A Ramesh et al. Open AI ɾౙͷ࣌୅͸աڈͷ΋ͷ ɾ೥͔ΒจॻಡղείΞ͸ਓؒҎ্ ɾ࠷ۙͷϒϨΠΫεϧʔͷଟ͘͸(PPHMFൃ ʢେྔͷϚγϯͱେྔͷݚڀऀ͕͍Δʣ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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΋͏গ͠۩ମతʹɾɾɾ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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ɾҰੲલ͸ɼϘτϜΞοϓͳղੳ͕ओྲྀ ᶃܗଶૉղੳ ୯ޠ෼ׂ ඼ࢺ൑ఆ ᶄߏจղੳ ۟ߏ଄΍܎Γड͚Λಉఆ ᶅΑΓਐΜͩλεΫ ࢦࣔޠ΍ݴ͍׵͑Λೝࣝ ڞࢀরղੳɾরԠղੳ จॻશମͷྲྀΕΛղੳ ஊ࿩ߏ଄ղੳ ԞଜֶΒࣗવݴޠॲཧγϦʔζߏจղੳ ίϩφࣾ IUUQTUXJUUFSDPNOBLBNVSBLJIJSPTUBUVTQIPUP ԞଜֶΒࣗવݴޠॲཧγϦʔζจ຺ղੳ ड़ޠ߲ߏ଄ɾরԠɾஊ࿩ߏ଄ͷղੳ ίϩφࣾ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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ɾҰੲલ͸ɼϘτϜΞοϓͳղੳ͕ओྲྀ ˣ ɾਂ૚ֶशʹΑΓɼਖ਼ղσʔλ͕େྔʹ͋Ε͹ʜ ɾਓ͕ؒஞҰϧʔϧΛࢦࣔ͠ͳͯ͘΋ ɾ్தͷղੳΛඈ͹ͯ͠Ұؾʹ ໰୊Λղ͚Δ͜ͱ͕૿͑ͨ ɾͰ͖Δ͜ͱͷ෯΋޿͕͍ͬͯΔ͠ɼੑೳ΋্͕͍ͬͯΔ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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ײ৘෼ੳ r :PV5VCF ɾίϝϯτ͕඄ᨱதইʹ͋ͨΔ͔൱͔൑ఆ ˠ ౤ߘલʹ஫ҙשى IUUQTUFDIDSVODIDPNZPVUVCFJOUSPEVDFTOFXGFBUVSFTUPBEESFTTUPYJDDPNNFOUT IUUQTTVQQPSUHPPHMFDPNZPVUVCFUISFBEGBRIPMEQPUFOUJBMMZJOBQQSPQSJBUFDPNNFOUTGPSSFWJFX IMFO ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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நग़ܕ࣭໰Ԡ౴ r (PPHMFݕࡧ ɾ8FCϖʔδΛબఆ ˠ ౴͑ʹ͋͏ՕॴΛநग़ ˠ ௚઀දࣔ IUUQTXXXKSTPSKQNPEVMFTDJUJ[FOJOEFYQIQ DPOUFOU@JE ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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ػց຋༁ r %FFQ- ʙ IUUQTXXXEFFQMDPNUSBOTMBUPS ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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ୈࡾճ ৽نӦۀઌ։୓ϓϩδΣΫτݕ౼ٞࣄ࿥ ೔ఔɿ ৔ॴɿຊࣾ"ձٞࣨ ࢀՃऀʢܟশུʣɿ˔˔՝௕ɺ˔˔ɺ˔˔ɺ˔˔ ৽نλʔήοτީิௐࠪ಺༰ͷڞ༗ͱબఆ  "*ͳͲͷ৽نٕज़ʹ਌࿨ੑͷߴ͍ΞʔϦʔΞμϓλʔ૚ʢ˔˔ʣ ૝ఆ௨Γڵຯؔ৺͸ڧ࣋ͪ͘ૣ͘ࢼ͍ͨ͠ͱ͍͏੠͕ଟ͔ͬͨɻ ͨͩྲྀߦʹහײͳ෼ɺ๞͖΋ૣ͘ɺ௕ظతͳλʔήοτͱͯ͠։୓͍ͯ͘͠ͷ͸ඇৗʹ೉͍͠ɻ  %*/,T૚ʢ˔˔ʣ ࣗ෼ͷ࣌ؒΛ๛͔ʹ͢ΔͨΊʹׂ͚Δ͕࣌ؒଟ͘ɺ ·ͨۚમతʹ΋༨༟͕͋Δ͜ͱ͕ଟ͘ඇৗʹ૬ੑΑ͍ɻ  ΞΫςΟϒγχΞ૚ʢ˔˔ʣ ΞΫςΠϒγχΞ૚͸1$΍εϚϗΛ׬શʹ࢖͍͜ͳ͍ͤͯΔ૚͕ଞͷηάϝϯτΑΓগͳ͍ͨΊվ ળޮՌ͸ඇৗʹେ͖͍ɻ ͨͩಋೖʹ͔͔Δίετ΋େ͖͘ଞͰ՝୊Λચ͍ग़͔ͯ͠Βͷ΄͏͕ྑ͍ͱߟ͑Δɻ ɾௐࠪ݁ՌΛ౿·͑%*/,T૚ΛϝΠϯλʔήοτͱͯ͠ݕ౼Λ͢͢ΊΔɻ ࣍ճ΁ͷ॓୊ࣄ߲ʢΞΫγϣϯϓϥϯʣ  %*/,T૚ϖϧιφ࡞੒ʢ˔˔ʣ %*/,T૚ͷϖϧιφ࡞੒ͷࡍʹஉঁͦΕͧΕͷଆͰͷ࡞੒͕๬·͍͠ɻ ·ͨൺֱͱ͍͏ҙຯͰ͸෉්ʹࢠڙҰਓͷύλʔϯ΋Ұͭ࡞ΔͱΑ͍ͷͰ͸ͳ͍͔ɻ  %*/,T૚΁ͷޮ཰తͳΞϓϩʔνͷબఆʢ˔˔ʣ %*/,T૚͸ωοτϝσΟΞͰ͸ԿΛಡΜͰ͍Δͷ͔ɻ৘ใऩू͸Ͳ͔͜Β͍ͯ͠Δͷ͔ɻීஈͷڵ ຯؔ৺͸Ͳͷ͋ͨΓʹ͋Δͷ͔ɻͳͲɻ  ෦௕ใࠂձʹ޲͚ͨใࠂࢿྉ࡞੒ʢ˔˔ˠ˔˔՝௕ʣ ࣍ճͷ෦௕ձͰ͸؅ঠ໾һ΋ࢀՃ༧ఆͷͨΊࠓ·ͰҎ্ʹࢿྉΛ࡞ΓࠐΉඞཁ͋Γɻ ·ͨਤΛଟ͘࢖͏ͱͱ΋ʹҰͭҰͭͷεϥΠυ͸୹͘੾Γ෼͚ͨ΋ͷ͕޷·ΕΔɻ IUUQTXXXEJHFTUFMZ[BBJ ୈࡾճɺ৽نӦۀઌ։୓ϓϩδΣΫτݕ౼ٞࣄ࿥͕೔ɺ։࠵͞ΕΔɻ ৽نλʔήοτީิௐࠪ಺༰ͷڞ༗ͱબఆɺ࣍ճ΁ͷ॓୊ࣄ߲ͷબఆɻ %*/,4૚ϖϧιφ࡞੒ɺ෦௕ใࠂձʹ޲͚ͨใࠂࢿྉ࡞੒ͳͲɻ ࣗಈཁ໿ r &-*;"%*(&45 ʙ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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ΞϚϏΤʢྺ࢙తԾ໊ݣɿΞϚϏϭʣ͸ɺ೔ຊʹ఻ΘΔ൒ਓ൒ڕͷ༯ոɻޫً࢟͘Ͱւத͔ΒݱΕɺ๛࡞΍ӸපͳͲͷ ༧ݴΛ͢Δͱ఻͑ΒΕ͍ͯΔɻߐށ࣌୅ޙظͷංޙࠃʢݱɾ۽ຊݝʣʹݱΕͨͱ͍͏ɻ͜ͷ࿩͸ૠਤ෇͖Ͱנ൛ʹऔΓ ্͛ΒΕɺԕ͘ߐށʹ·Ͱ఻͑ΒΕͨɻ߂Խ೥݄த०ʢ೥্݄०ʣͷ͜ͱɺຖ໷ɺւதʹޫΔ෺ମ͕ग़຅ͯ͠ ͍ͨͨΊɺ໾ਓ͕ෝ͍ͨͱ͜ΖɺͦΕ͕࢟Λݱͨ͠ɻ࢟ܗʹ͍ͭͯݴ༿Ͱ͸ॻ͖ཹΊΒΕ͍ͯͳ͍͕ɺૠਤ͕ఴ͑ΒΕ ͍ͯΔɻ ͦͷऀ͸ɺ໾ਓʹରͯ͠ʮࢲ͸ւதʹॅΉΞϚϏΤͱਃ͢ऀͳΓʯͱ໊৐Γɺʮ౰೥ΑΓϲ೥ͷؒ͸ॾࠃͰ ๛࡞͕ଓ͕͘Ӹප΋ྲྀߦ͢Δɻࢲͷ࢟Λඳ͍ͨֆΛਓʑʹૣʑʹݟͤΑɻʯͱ༧ݴΊ͍ͨ͜ͱΛࠂ͛ɺւͷத΁ͱؼͬ ͯߦͬͨɻ೥୅͕ಛఆͰ͖Δ࠷ݹͷྫ͸ɺఱอ೥ʢ೥ʣͷӽޙࠃʢݱɾ৽ׁݝʣʹग़ݱͨ͠ʮւ඙ʢಡΈͷਪ ఆɿ͋·ͼ͜ʣʯΛهड़ͨ͠נ൛ʢʰ௶઒ຊʱͱ͍͏ɻ෱Ҫݝཱਤॻؗॴଂʣɺͦͷૠֆʹඳ͔Εͨւ඙͸ɺ಄͔Β͍ ͖ͳΓຊͷ଍͕ੜ͑ͨʢ಑ମͷͳ͍ʣܗঢ়ͰɺਓؒͷΑ͏ͳࣖΛ͠ɺ໨͸·Δ͘ɺޱ͕ಥग़͍ͯ͠Δɻͦͷ೥தʹ೔ຊ ਓޱͷׂͷࢮ໓Λ༧ݴ͠ɺͦͷ૾ͷֆࡳʹΑΔٹࡁΛ஧ࠂ͍ͯ͠Δɻ ΫΠζࣗಈੜ੒ r (PPHMF5 ʙ ɾࢿྉͱ౴͑ʹ͋ͬͨ໰୊จΛੜ੒͢Δ IUUQTDPMBCSFTFBSDIHPPHMFDPNHJUIVCTPOPJTBEFFQRVFTUJPOHFOFSBUJPOCMPCNBJOU@KBQBOFTF@RVFTUJPO@HFOFSBUJPOJQZOC ࢿྉ ౴͑ ංޙࠃʢݱɾ۽ຊݝʣ ߐށ࣌୅ͷͲͷࠃʹ ΞϚϏΤ͕ݱΕͨͷ Ͱ͔͢ ໰୊ ຊ ʮւ඙ʯʹ͸ ଍͕͍ͭ͘ ͋Γ·͔ͨ͠ ๛࡞΍ӸපͳͲ ΞϚϏΤ͸ւத͔Β ԿΛ༧ݴ͢Δͱ ݴΘΕ͍ͯ·͔͢ ໰୊ ໰୊ ౴͑ ౴͑ ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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ςΩετ͔Βͷը૾ੜ੒ r 0QFO"* %"--& ʙ IUUQTPQFOBJDPNCMPHEBMMF ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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ର࿩γεςϜ r ΤΞϑϨϯυ ʙ IUUQTBJSGSJFOEBJKB ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠

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·ͱΊ 01 ͜ͱ͹ͷ"*͸Ͳ͜·ͰਐԽ͔ͨ͠ʁ ͢ͰʹจॻಡղείΞ͸ਓؒΛ͓͑ͯ͜Γɼ Ұ෦ͷλεΫͰ͸ਓؒͱ۠ผ͕͖ͭʹ͍͘͜ͱ΋

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͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔

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IUUQTKBQBO[EOFUDPNBSUJDMFΑΓվม ͳͥɼ"*͸·ͩ໘౗ͳ࢓ࣄΛ ୣͬͯ͘Εͳ͍ͷ͔ʁ ݬ໓ظ ਓ޻஌ೳ ͦΖͦΖ໘౗ͳ࢓ࣄΛୣͬͯ͘ΕΔ͸ͣͰ͸ʜʁ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔

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ҩྍݱ৔ ɾͳ͔ͳ͔࢓ࣄ͕ࣗಈԽ͞Εͳ͍ "*ݚڀऀ Ұ෦ͷҙݟ ɾ˓˓ͷ৬ۀ͸"*ʹୣΘΕΔʂ ɾ์ࣹઢՊҩ͸ཁΒͳ͍ʂ Ϊϟοϓ IUUQTUXJUUFSDPN&SJD5PQPMTUBUVT TΑΓվม ͦΖͦΖ໘౗ͳ࢓ࣄΛୣͬͯ͘ΕΔ͸ͣͰ͸ʜʁ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔

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೥݄ݱࡏɼ '%"ঝೝ͞Εͨҩྍ"*ػثʹ ࣗવݴޠॲཧΛओػೳͱͨ͠΋ͷ͸ݟ͔ͭΒͳ͍ ˞੡඼ͷ  L 1SFNBSLFU/PUJGJDBUJPO4VNNBSZͷจॻதʹ MBOHVBHFQSPDFTTJOHPSUFYUNJOJOHΛؚΉ݅਺ ݅ ˞ػೳͷҰ෦ͱͯ͠ಡӨϨϙʔτ࡞੒ࢧԉΛᨳ͍ͬͯΔ΋ͷͳͲ͸͋Δ ྫ.&%05IZSPJE .&%0%91UF-UE IUUQTXXXGEBHPWNFEJDBMEFWJDFTTPGUXBSFNFEJDBMEFWJDFTBNEBSUJGJDJBMJOUFMMJHFODFBOENBDIJOFMFBSOJOHBJNMFOBCMFENFEJDBMEFWJDFT ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔

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࢒೦ͳ͕Βɼݱ৔Ͱͷ࣮༻Խ͸·ͩ ˣ ͳ͔ͥʁ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔

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⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "FUBM.FUB-FBSOJOHXJUI*NQMJDJU(SBEJFOUT/FVS*14  )BO)FUBM3FMBUJPO/FUXPSLTGPS0CKFDU%FUFDUJPO$713 4..D,JOOFZFUBM*OUFSOBUJPOBMFWBMVBUJPOPGBO"*TZTUFNGPSCSFBTUDBODFSTDSFFOJOH/BUVSF ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ

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⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "FUBM.FUB-FBSOJOHXJUI*NQMJDJU(SBEJFOUT/FVS*14  )BO)FUBM3FMBUJPO/FUXPSLTGPS0CKFDU%FUFDUJPO$713 4..D,JOOFZFUBM*OUFSOBUJPOBMFWBMVBUJPOPGBO"*TZTUFNGPSCSFBTUDBODFSTDSFFOJOH/BUVSF ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ

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⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "FUBM.FUB-FBSOJOHXJUI*NQMJDJU(SBEJFOUT/FVS*14  )BO)FUBM3FMBUJPO/FUXPSLTGPS0CKFDU%FUFDUJPO$713 4..D,JOOFZFUBM*OUFSOBUJPOBMFWBMVBUJPOPGBO"*TZTUFNGPSCSFBTUDBODFSTDSFFOJOH/BUVSF ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ

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⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "FUBM.FUB-FBSOJOHXJUI*NQMJDJU(SBEJFOUT/FVS*14  )BO)FUBM3FMBUJPO/FUXPSLTGPS0CKFDU%FUFDUJPO$713 4..D,JOOFZFUBM*OUFSOBUJPOBMFWBMVBUJPOPGBO"*TZTUFNGPSCSFBTUDBODFSTDSFFOJOH/BUVSF ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ

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⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "FUBM.FUB-FBSOJOHXJUI*NQMJDJU(SBEJFOUT/FVS*14  )BO)FUBM3FMBUJPO/FUXPSLTGPS0CKFDU%FUFDUJPO$713 4..D,JOOFZFUBM*OUFSOBUJPOBMFWBMVBUJPOPGBO"*TZTUFNGPSCSFBTUDBODFSTDSFFOJOH/BUVSF ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ

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⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "FUBM.FUB-FBSOJOHXJUI*NQMJDJU(SBEJFOUT/FVS*14  )BO)FUBM3FMBUJPO/FUXPSLTGPS0CKFDU%FUFDUJPO$713 4..D,JOOFZFUBM*OUFSOBUJPOBMFWBMVBUJPOPGBO"*TZTUFNGPSCSFBTUDBODFSTDSFFOJOH/BUVSF ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ

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⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "FUBM.FUB-FBSOJOHXJUI*NQMJDJU(SBEJFOUT/FVS*14  )BO)FUBM3FMBUJPO/FUXPSLTGPS0CKFDU%FUFDUJPO$713 4..D,JOOFZFUBM*OUFSOBUJPOBMFWBMVBUJPOPGBO"*TZTUFNGPSCSFBTUDBODFSTDSFFOJOH/BUVSF ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ ޻ֶܥ ݚڀऀ ҩֶܥ ݚڀऀ

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⁞ "*جૅٕज़ͷൃల "*ͷ࢓૊Έʹର͢Δཧ࿦తɾجૅతͳݚڀ   ը૾ॲཧࣗવݴޠॲཧͷൃల "*ݚڀ༻ͷඇҩྍσʔλΛ࢖ͬͨݚڀ ⁡ ҩྍݱ৔Ͱͷݕূ ҩྍݱ৔ʹ࣮ࡍʹߩݙ͢Δ͔Ͳ͏͔ʁ 3BKFTXBSBO "FUBM.FUB-FBSOJOHXJUI*NQMJDJU(SBEJFOUT/FVS*14  )BO)FUBM3FMBUJPO/FUXPSLTGPS0CKFDU%FUFDUJPO$713 4..D,JOOFZFUBM*OUFSOBUJPOBMFWBMVBUJPOPGBO"*TZTUFNGPSCSFBTUDBODFSTDSFFOJOH/BUVSF ⁢ ҩྍݱ৔΁ͷಋೖ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ⁠ ҩྍσʔλͰͷݕূ ҩ༻ը૾΍ిࢠΧϧςΛՃ޻ͨ͠ެ։σʔλ΍ɼ ຊ෺ͷ୯ࢪઃʙଟࢪઃσʔλͰͷݚڀ ٕज़ྲྀೖʹ͸͕͔͔࣌ؒΔ ·ͩϋʔυϧ͕ߴ͍ ͜ͷݚڀ͸׆ൃ

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͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ྫɿಡӨϨϙʔτͷࣗಈੜ੒ "*ݚڀɿΩϟϓγϣϯੜ੒λεΫ ɾຕͷը૾͔Β୹จΛੜ੒ ɾݫີ͞͸͞΄Ͳ໰ΘΕͳ͍ ์ࣹઢՊҩϨϕϧͷಡӨϨϙʔτ࡞੒ ɾຕʙଟ਺ͷը૾͔Β ɾ೥ྸ ੑผ ྟচ৘ใ աڈը૾΋Έͯ௕จΛੜ੒ ɾ಺༰ͷݫີ͕͞ٻΊΒΕΔ ϋʔυϧ͕ߴ͍ :1BOFUBM.FE8SJUFS,OPXMFEHF"XBSF.FEJDBM5FYU(FOFSBUJPO*OQSPDFFEJOHTPGUIFUI*OUFSOBUJPOBM$POGFSFODFPO$PNQVUBUJPOBM-JOHVJTUJDT $0-*/( 

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8V4FUBM%FFQMFBSOJOHJODMJOJDBMOBUVSBMMBOHVBHFQSPDFTTJOHBNFUIPEJDBMSFWJFX+"N.FE*OGPSN"TTPD    ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ը૾"*ͱ͘Β΂ͯ਺೥஗Ε͍ͯΔ͕ɼ ݚڀ͸ٸ଎ʹ੝Γ্͕͖͍ͬͯͯΔ ҩྍจॻʹਂ૚ֶशΛద༻ͨ͠࿦จͷຊ਺   +BO"QS 

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Ͱ͸ɼͲͷΑ͏ͳݚڀ͕͞Ε͍ͯΔ͔ʁ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔

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ҩྍจॻ ΧϧςͳͲ ࿦จ ױऀςΩετ ҩྍݴޠॲཧ͕ओʹѻ͏σʔλͭ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔

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ҩྍจॻ ΧϧςͳͲ ࿦จ ױऀςΩετ ҩྍݴޠॲཧ͕ओʹѻ͏σʔλͭ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔

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ࣗಈείΞϦϯά ɾ৺๪ࡉಈױऀͷΧϧς͔Β೴ߎ࠹ϦεΫ $)" %4 7"4D ΍ ग़݂ϦεΫ )"4#-&% Λࣗಈ൑ఆ ɾ$)" %4 7"4Dʾɼ)"4#-&%ʾʹର͢Δ ཅੑతத཰ʙ 4IJSMFZ78BOHFUBM6TFPGFMFDUSPOJDIFBMUIDBSFSFDPSETUPJEFOUJGZDPNQMFYQBUJFOUTXJUIBUSJBMGJCSJMMBUJPOGPSUBSHFUFE JOUFSWFOUJPO+PVSOBMPGUIF"NFSJDBO .FEJDBM*OGPSNBUJDT"TTPDJBUJPO 7PMVNF *TTVF .BSDI 1BHFTr ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ Partners HealthCare System Research Patient Data Registry (RPDR) 480 patient charts CHA2 DS2 -VASc score= ? HAS-BLED score = ?

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֎དྷΧϧςࣗಈ࡞੒ r $MVTUFSTFOU ɾ֎དྷԻ੠ͷจࣈى͜͠Λ40"1ܗࣜͷΧϧςʹࣗಈม׵ ɾӳޠެ։σʔληοτ ".*.FFUJOH$PSQVTΛར༻ ,VOEBO,FUBM(FOFSBUJOH40"1/PUFTGSPN%PDUPS1BUJFOU$POWFSTBUJPOT6TJOH.PEVMBS4VNNBSJ[BUJPO5FDIOJRVFT"$- +$BSMFUUBFUBM6OMFBTIJOHUIFLJMMFSDPSQVTFYQFSJFODFTJODSFBUJOHUIFNVMUJFWFSZUIJOH".*.FFUJOH$PSQVT-3&$ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔

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ྟচࢼݧͷద֨ੑͷࣗಈ൑ఆ ɾ౶೘පױऀ໊ʹ͍ͭͯΧϧςΛ΋ͱʹݸͷج४Λ൑ఆ͠ ྟচࢼݧͷ૊ΈೖΕج४ΛΈ͔ͨ͢Ͳ͏͔ࣗಈ൑ఆ 'TDPSFΛୡ੒ :9JPOH FUBM$PIPSUTFMFDUJPOGPSDMJOJDBMUSJBMTVTJOHIJFSBSDIJDBMOFVSBMOFUXPSL+PVSOBMPGUIF"NFSJDBO.FEJDBM*OGPSNBUJDT"TTPDJBUJPO    r ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ Met? Non-met?

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ҩྍจॻ ΧϧςͳͲ ࿦จ ױऀςΩετ ҩྍݴޠॲཧ͕ओʹѻ͏σʔλͭ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔

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ѱੑजᙾͷ QSFDJTJPONFEJDJOFࢧԉ ɾ͍ΘΏΔ ΦʔμʔϝΠυҩྍ΁ͷԠ༻Λ૝ఆ ɾ৚݅ʹద࣏ͨ͠ྍ๏Λ;͘Ήจݙ΍ྟচࢼݧΛࣗಈݕࡧ ,3PCFSUTFUBM0WFSWJFXPGUIF53&$1SFDJTJPO.FEJDJOF5SBDL*OQSPDFFEJOHTPGUIF5XFOUZ&JHIUI5FYU3FUSJFWBM$POGFSFODF 53&$  ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ࣬ױ໊ Ҩ఻ࢠมҟ ೥ྸ ੑผ จݙΛࣗಈͰఏࣔ ˠਫ਼౓ʙ ࢼݧΛࣗಈͰఏࣔ ˠਫ਼౓ʙ PubMed ClinicalTrials.gov

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ϝλΞφϦγεͷࣗಈԽ ɾର৅࿦จ͔ΒࣗಈͰ৘ใநग़͠ɼϝλղੳΛߦ͏ '8.VUJOEB FUBM"650.&5""VUPNBUJD.FUB"OBMZTJT4ZTUFN&NQMPZJOH/BUVSBM-BOHVBHF1SPDFTTJOH.&%*/'0 ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔

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ҩྍจॻ ΧϧςͳͲ ࿦จ ױऀςΩετ ҩྍݴޠॲཧ͕ओʹѻ͏σʔλͭ ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔

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4/4ʹΑΔҩༀ඼҆શੑ؂ࢹ QIBSNBDPWJHJMBODF ɾҩྍϑΥʔϥϜͳͲͷױऀ౤ߘςΩετ͔Β༗֐ࣄ৅Λݕग़ ɾ'%"ʹΑΔܯࠂ΍ఴ෇จॻվగͷঝೝΑΓલʹೝࣝ͑ͨ͠ྫ΋ 3'FMENBOFUBM6UJMJ[JOH5FYU.JOJOHPO0OMJOF.FEJDBM'PSVNTUP1SFEJDU-BCFM$IBOHFEVFUP"EWFSTF%SVH3FBDUJPOT,%%1SPDFFEJOHTPGUIFUI"$. 4*(,%%*OUFSOBUJPOBM$POGFSFODFPO,OPXMFEHF%JTDPWFSZBOE%BUB.JOJOH ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ ྫελνϯʹΑΔೝ஌ػೳ௿Լ ೥ '%"վగঝೝ  ˡ ೥·Ͱͷױऀ౤ߘ͔Βݕग़Մೳ Drug Approval FDA Approval of Safety Related Label Changes

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·ͱΊ 02 ͜ͱ͹ͷ"*͸Ͳ͜·Ͱҩྍʹߩݙ͍ͯ͠Δ͔ʁ ࣮༻Խʹ͸·ͩڑ཭͕͋Δ͕ɼ ҩྍݱ৔ͷ՝୊ʹ͍ۙݚڀ͸૿͖͍͑ͯͯΔ

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͜ͱ͹ͷ"*Λ΋ͬͱҩྍʹ׆͔ͨ͢Ίʹ͸

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͜ͱ͹ͷ"*Λ΋ͬͱҩྍʹ׆͔ͨ͢Ίʹ͸ ৘ใܥͷ"*ݚڀऀ͚ͩͰ͸ͳ͘ɼ ҩֶܥͷ"*ݚڀऀ΋Ұॹʹ੝Γ্͍͛ͯ͘ඞཁ͕͋Δ ٕज़తʹͰ͖Δ͜ͱ CZ৘ใܥݚڀऀ ղܾ͍ͨ͠໰୊ CZҩֶܥݚڀऀ ࣮༻Խ

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͜ͱ͹ͷ"*Λ΋ͬͱҩྍʹ׆͔ͨ͢Ίʹ͸ ৘ใܥͷ"*ݚڀऀ͚ͩͰ͸ͳ͘ɼ ҩֶܥͷ"*ݚڀऀ΋Ұॹʹ੝Γ্͍͛ͯ͘ඞཁ͕͋Δ ٕज़తʹͰ͖Δ͜ͱ CZ৘ใܥݚڀऀ ղܾ͍ͨ͠໰୊ CZҩֶܥݚڀऀ ࣮༻Խ ҩྍσʔλ͕ೖखͰ͖ͳ͍ʜ ҩྍݱ৔ͷχʔζ͕Θ͔Βͳ͍ʜ ͱ͖ͬͭʹ͍͘ʜ

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͜ͱ͹ͷ"*Λ΋ͬͱҩྍʹ׆͔ͨ͢Ίʹ͸ ͭͷղܾࡦ ʹ 4IBSFEUBTL ɾҩྍݱ৔ͷχʔζʹ߹ͬͨ໰୊ઃఆΛͯ͠σʔλΛ࡞੒ɾެ։͠ɼ ޿͘ݚڀऀ͔Βղ๏Λืू͢Δ ӳޠ ɾ/BUJPOBM/-1$MJOJDBM$IBMMFOHFT OD CZ)BSWBSE.FEJDBM4DIPPM ೔ຊޠ ɾ/5$*3CZࠃཱ৘ใֶݚڀॴ /** Χϧςࣗಈಗ໊Խ ༀࡎྺநग़ ࢦࣔޠ ݴ͍׵͑ ྟচࢼݧ૊ΈೖΕ දهΏΕղফ ࣏ྍ໨తͷཧղ ɾ53&$CZถࠃඪ४ٕज़ݚڀॴ /*45 4/4͔Βͷ ײછ঱ྲྀߦ༧ଌ ಡӨϨϙʔτ ߏ଄ԽɾಉҰ঱ྫ൑ఆ ʙ 1SFDJTJPO.FEJDJOFࢧԉ

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͜ͱ͹ͷ"*Λ΋ͬͱҩྍʹ׆͔ͨ͢Ίʹ͸ ·ͩ೔ຊࠃ಺ͷݚڀऀ͕গͳ͘ɼख෇͔ͣͷςʔϚ͕ଟ͍ ֶज़ػؔ ҩֶ ɾ౦େපӃ ์ࣹઢՊ ΠϝʔδϥϘ ɾ౦େපӃ ҩྍ"*։ൃֶߨ࠲ ɾ౦େපӃ ҩྍ৘ใ෦ ɾࡕେපӃ ҩྍ৘ใ෦ ɾஜ೾େපӃ ҩྍ৘ใ෦ ͳͲ ֶज़ػؔ ޻ֶ ɾಸྑઌ୺େ ιʔγϟϧɾίϯϐϡʔςΟϯάݚڀࣨ ͳͲ ɾஜ೾େ ώϡʔϚϯίϯϐϡςʔγϣϯݚڀࣨ ͳͲ اۀ ɾ෋࢜θϩοΫε ͳͲ

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͜ͱ͹ͷ"*Λ΋ͬͱҩྍʹ׆͔ͨ͢Ίʹ͸ ೔ຊͰ΋গͣͭ͠ҩྍσʔλ΍ֶशࡁϞσϧ͕࢖͑ΔΑ͏ʹ ֶशࡁݴޠϞσϧ ɾ65)#&35CZ౦େපӃ ҩྍ"*։ൃֶߨ࠲ ެ։σʔλ ɾ঱ྫใࠂίʔύε CZ౦େපӃ ҩྍ"*։ൃֶߨ࠲ ɾٖࣅΧϧς CZஜ೾େපӃ ҩྍ৘ใ෦ ɾಡӨϨϙʔτίʔύε .FE5YU33 CZಸྑઌ୺େ ɾ঱ྫใࠂίʔύε .FE5YU$3 CZಸྑઌ୺େ

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·ͱΊ 03 ͜ͱ͹ͷ"*Λ΋ͬͱҩྍʹ׆͔ͨ͢Ίʹ͸ʁ ଴͍ͬͯΔ͚ͩͰ͸ͳ͔ͳ͔׆͔͞Εͳ͍ ৘ใܥݚڀऀ͚ͩͰ͸ɼݱ৔໨ઢͷ໰୊ఏى͕͠ʹ͍͘ ҩྍଆ͔Β΋੝Γ্͍͖͛ͯ·͠ΐ͏ʂ

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·ͱΊ 01 ͜ͱ͹ͷ"*ͷจॻಡղείΞ͸͢ͰʹਓؒΛ͑͜ɼ Ұ෦ͷλεΫͰ͸ਓؒͱ۠ผ͕͖ͭʹ͍͘͜ͱ΋ 02 ͜ͱ͹ͷ"*ͷҩྍ΁ͷ࣮༻Խʹ͸·ͩڑ཭͕͋Δ͕ɼ ҩྍݱ৔ͷ՝୊ʹ͍ۙݚڀ͸૿͖͍͑ͯͯΔ 03 "*͸଴͍ͬͯΔ͚ͩͰ͸ҩྍݱ৔ʹͳ͔ͳ͔͜ͳ͍ ҩྍଆ͔Β΋੝Γ্͍͖͛ͯ·͠ΐ͏ʂ

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