Ontdek de kracht van Posit bij het Jessa-ziekenhuis Annick Daniels Wetenschapper – Klinisch laboratorium Thomas Wouters Account Manager Business Insights

Agenda Welkom & introductie door AXI Wie zijn wij & Wie is aanwezig? 2 use-cases van shiny-apps, Opzet van het Posit-Connect platform Uitleg BALLETT-studie - Platform dat wordt gedeeld binnen 13 ziekenhuizen in België voor de dienst oncologie Uitleg Posit producten + demo Connect Q&A & Afsluiting

Annick Daniels Wetenschapper – Klinisch laboratorium Jessa-ziekenhuis case

Het Jessa-ziekenhuis in cijfers

Finance consolidatie applicatie • Shiny-applicatie BALLETT-applicatie voor oncologie • Shiny-applicatie Use-cases

Posit connect Ubuntu22.04 R & Python Opzet Connect-platform

R Shiny app Finance Allocatie ✓ Doel: ✓ Inzicht in de oorzaak van evolutie van BFM op niveau kostenplaats ✓ Vergelijk tussen kostenplaatsen ✓ Alarmtabel voor wijzigingen van sleutels en boekingen ✓ Overzicht toegepaste allocatie methoden ✓ Status: ✓ Zeer bruikbare tool ✓ Visualisatie m.b.v. R shiny app: dashboard ✓ Plannen ✓ Upgrade i.s.m. AXI ✓ Meer selecties ✓ Trend visualisatie ✓ Layout Frederic Vanswijgenhoven

BALLET STUDIE: Participating parties offering broad support • Belgian Scientific Institute of Public Health: • Advises the Belgian government on NGS indications and requirement for reimbursement (ComPerMed.be) • Belgian Society of Medical Oncology: • National scientific working group for oncologists • Commercial parties Annick Daniels Klinisch laboratorium Moleculaire

BALLETT-Studie ✓ Belgian Approach of Local Laboratory Extensive Tumor Testing ✓ Project waar 13 verschillende Belgische ziekenhuizen aan meewerken ✓ Doel: Meerwaarde te onderzoeken van uitgebreid tumoronderzoek (Comprehensive Genomic Profiling of CGP) bij de toewijzing van een gepaste behandeling bij kankerpatiënten ✓ CGP focust op het vinden van zowel kleine genetische mutaties alsook grotere genetische varianten + enkele andere tumor gerelateerde genetische parameters

BALLETT-Studie ✓ Noden: ✓ Snelle en gemakkelijke beschikbaarheid van gegevens van een patiënt voor wekelijkse bespreking op MolecularTumor Board ✓ Dashboard met algemene statistieken over alle patiënten heen ✓ Rekening houden met: ✓ Veiligheid ✓ Overzichtelijkheid ✓ Eenvoudig te delen

Z01 Z02 Z03 Z04 Z05 Z06 Z07 Z08 Z09 Z10 Z11 Z12 Z01 Z02 Z03 Z04 Z05 Z06 Z07 Z08 Z09 Z10 Z11 Z12 Dashboard > Tabs met samenvattende statistieken over studie heen > tab Patients

Overzicht van patiënten te bespreken op MTB patA patB patC patC patE patF patG

Data per patiënt > tab Comprehensive Genomic Profiling (CGP) results PatX 65 Cancer X X 05/02/2023

Data per patiënt > rapport – preview en te downloaden als pdf Who PatX PatX X 65 Cancer X 05/02/2023

AXI & Posit Thomas Wouters Account Manager Business Insights

onderbouwd.duurzaam.dichtbij AXI in cijfers

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⌵ ⌵ POSIT SOLUTIONS Posit Workbench Analyze data and create insights using R and Python Posit Workbench is the enterprise-level integrated development environment for data scientists who need to develop, collaborate, and scale in R and Python. • Program in your preferred IDE (RStudio, VSCode, JupyterLab, Jupyter Notebook) • Load balance between servers • Connect to your data with Posit Professional Drivers • Collaborate and share projects • Scale with Kubernetes, SLURM, and other HPC environments • Stay safe with authentication, access, & security • Run multiple concurrent R and Python sessions • Execute remote sessions with Launcher • Stay aware with auditing and monitoring • Manage R and Python sessions • Receive end-user support documentation learn more...

⌵ ⌵ Posit Package Manager Organize and manage packages that data scientists need to create and share insights POSIT SOLUTIONS Posit Package Manager is a repository management server to organize and manage R and Python packages across your organization. • Access to CRAN, Bioconductor, and PyPI mirrors • Publish and share internal packages • Restrict package access • Pre-built Linux binaries • Bring your own binaries • Restrict package access • Find packages across repositories • Offline access to sources if required documentation learn more...

⌵ ⌵ POSIT SOLUTIONS Posit Connect Share insights with decision-makers, via web applications, email, or APIs Posit Connect is the enterprise-level platform for hosting and sharing your data science products. • Shiny for R, Shiny for Python, Dash, Bokeh, and Streamlit applications • R Markdown and Quarto reports, dashboards, websites and more • Jupyter Notebooks • Plumber, FastAPI, and Flask APIs Connect provides: • Custom authentication configurations • Scheduled republishing of reports • Curation tools for your content items documentation learn more...

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Category Description Shiny server Open Source Posit Connect Shinyapps.io Overview Commercial License (not AGPL) RStudio Support Deploy Shiny applications to the Web Push-button publishing from RStudio IDE Deploy and access Shiny apps, dashboards, R Markdown reports, static plots, and APIs in one place Deploy and access Python-based content, including Flask, Dash, Streamlit and Bokeh Scheduled updates and distribution of reports Self-managed content - see and manage what you’ve published or can access from others Publishers only Support Professional Drivers - connect to some of the most popular databases Connect vs Shiny Server vs Shinyapps.io

Category Description Shiny server Open Source Posit Connect Shinyapps.io Security & Authentication Password protect applications Deploy Shiny applications behind firewalls Controlled access via SSL and LDAP, Active Directory, Google OAuth, PAM, proxied authentication, or passwords Tuning & Scaling Scale applications across multiple R processes Persistent R processes for faster load times Metrics & Management Performance and resource metrics Health check endpoint Connect vs Shiny Server vs Shinyapps.io

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