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Empowering Patients through Machine Learning-Driven Health Interventions

Empowering Patients through Machine Learning-Driven Health Interventions

Mareena Mallory from Memotext talks about how to empower patients using tools built with Python.

PyLadies Toronto

January 24, 2019
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  1. OUR MISSION Our mission: Make health data useful We empower

    patients to reach their healthcare goals and improve the bottom line for healthcare stakeholders.
  2. A4i A platform for supporting the schizophrenia and psychosis recovery

    process Our Mission: to extend care beyond the walls of the current mental health continuum, extend support, reduce isolation, and provide insights on the risk of relapse
  3. Complex Behavioral Health ADHD ALZ Dementia Maternal Health • Canada’s

    first prenatal adaptive SMS education program • Commercialized and endorsed by the Society of Obstetrics of Canada • Predicting readmissions, ↑ support, reducing isolation for Schizophrenia populations • Feasibility: retention 94% and significant improvements in psychiatric symptoms and personal recovery • Simple Online Family Intervention for ADHD • Evidence-based adaptive adherence for pharma manufacturers and physician groups • Feasibility shows 50% improvement in intervention group • Awarded grant funding by the Centre of Aging and Brain Health Innovation • Pilot a solution with a large home care provider in Canada, utilizing the Amazon Echo to communicate with seniors with dementia and to support caregivers MEMOTEXT PARTNERSHIP PROGRAMS All technology is built on MEMOTEXT Sentinel™ Core Engine
  4. Social Activation Living with Schizophrenia Stress and Anxiety Motivation and

    Cognition 15% 20% 20% 45% Intake assessment • 7 questions targeting the 4 content domains • User responses feed into segmentation model • Model produces custom distribution of content in real time for each person. • Updated Content Domains Custom Content Distribution Content Segmentation Algorithm
  5. Use Cases + Results Data Integration Customer Medication Adherence ↑31.4%

    Claims Ambient Phone Data Patient Self-Report Treatment Discontinuation ↓50% statin/hypertension Wearables Pharma/Pharmacy Payors PBM Providers MEMOTEXT SYSTEMS: SELECT USE CASE RESULTS Refill Persistence ↑37.3% HEDIS/Star Ratings Disease Literacy +85% Care Coordination ↓1.5 hr/week case manager time Patient Retention 91% Predictive Surveillance
  6. • A necessity to better navigate and manage chronic illness

    • Lack of timely targeted communications • Need for engagement to meet health goals • An inability to predict patient outcomes, behaviors and costs • Disconnect between appropriate interventions and risk identification • Gaps in care coordination Patient Stakeholder Why AI/ML?
  7. Where we are Where we need to be Descriptive &

    Retrospective Predictive & Prescriptive Why AI/ML?
  8. Why AI/ML? Machine Learning Disease Trajectory Mapping Connected Health Data

    Personalized Support • Claims • Risk Assessment Data • Demographics • Wearables • Ambient Phone/iOT • Feature Engineering • Adherence Clustering • Predicting Treatment Complexity / Therapy • Targeted Adherence Interventions • Care Navigator Bots • Multi-Channel Disease Interventions + Risk Identification
  9. Implementation Business Problem Definition KPI Definition, Validation Data Collection /

    Cleaning, Feature Engineering Data Exploration & ML Modelling Identify Intervention Nodes Identify Target Population(s)
  10. Step 1: Identify the Business Problem ✓ Frame your business

    problem • Describe the business opportunity, threat or issue at hand Example: ‘Hospitalization is a poor health outcome and very costly for schizophrenia/psychosis patient population. We want to know who is at risk.’
  11. MEMOTEXT Examples: Q: Can we identify those at risk of

    switching off of monotherapy? Q: Can we figure out who is likely to develop X in the next year? 2 years? Q: Can we determine who will likely stop taking their medication? Q: Can we identify who will become a high cost patient?
  12. Step 2: Define the KPIs • Consider your stakeholders and

    their business goals • If we are interested in high cost patients, how are we defining high-cost? Starting on expensive therapy? Top 5% of high cost users in a given year? OR
  13. Step 3: Collect, clean, build features! • Extract the data

    that is relevant in solving the business problem • Clean it • Removing irrelevant data • Ensure validity, remove corrupt/ inaccurate records • Structural errors • Outliers • Account for missing data • Proper data types • Data linking
  14. ✓ Size ✓ Location ✓ Bedrooms Step 3: Collect, clean,

    build features! Feature = An ATTRIBUTE or CHARACTERISTIC of something
  15. Provider Complexity Raw Data Patient Pharmacy Sarah A Alex B

    Alex D Alex C Sarah A Alex B Sarah A Feature Engineering Engineered Feature Patient Number of Unique Pharmacies Visited Sarah 1 Alex 3 WHAT IS FEATURE ENGINEERING? Step 3: Collect, clean, build features!
  16. Unsupervised Learning We try to uncover patterns within the data

    with no labels provided. Diabetes Supervised Learning We train the models on labelled data (known outcome) to predict on unseen data. No Diabetes Step 4: Data Exploration and ML Modelling
  17. Step 4: Data Exploration and ML Modelling Historical Data Training

    Model Prediction Learning from past cases Is this patient likely to discontinue treatment?
  18. Step 4: Data Exploration and ML Modelling Historical Data Training

    Model Prediction Learning from past cases Is this patient likely to discontinue treatment? Actual Outcome Data Surveillance Patient stopped claiming for medication X.
  19. Step 5: Identify Intervention Nodes • Can the problem be

    solved? Where in the patient journey will we intervene to make a difference? What are the levers? Identify intervention node
  20. Step 6: Identify Target Population • Who are the right

    patients to receive the intervention? • What types of patients will have a different experience within the intervention? Entire patient population Those who stand to benefit! High risk group No Risk High Risk of Tx. Discontinuation
  21. Which individuals will be affected by this tool? At which

    point in the journey will this be implemented? Into whose workflow will this fit into? What’s the end goal and how will this tool help? Overview: Putting All of the Pieces Together
  22. Which individuals will be affected by this tool? At which

    point in the journey will this be implemented? Into whose workflow will this fit into? What’s the end goal and how will this tool help? Overview: Putting All of the Pieces Together Patients with schizophrenia/ psychosis. Reduce readmissions. By identifying those at risk to intervene early. Outside of the clinical setting based on interaction with app. Patient’s physician. Example: schizophrenia/psychosis readmission.
  23. Empowering patients by providing them with the tools and resources

    they need to take control of their health
  24. Personalizing and tailoring programs with machine learning- driven insights to

    optimize intervention uptake, adherence, and success
  25. Evidence Based • Personalized • Validated • Integrated • Secure

    Thank you! GET IN TOUCH Mareena Mallory, Data Engineer [email protected] www.memotext.com 877.MEMO.TXT @memotext