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Proteomics in Research and Developmet

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February 18, 2025
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Proteomics in Research and Developmet

Avatar for elucidata

elucidata

February 18, 2025
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  1. Proteomics Data in R&D Elucidata helps harmonize in-house proteomics data

    and find relevant datasets from PRIDE and CPTAC, fit for downstream analysis and insight generation.
  2. Challenges with Accessing and Using Uncurated Proteomics Data • Lack

    of Standardization • Data Heterogeneity from In-house Assays • Data Volume requiring Curation • Data Processing and Analysis • Lack of Annotations • Lack of Sample Information
  3. • Elucidata’s data harmonization platform, Polly, harmonizes proteomics data from

    public, in- house sources, and stores them on an Atlas (or a destination of their choosing) in ML-ready formats. • Polly's powerful harmonization engine processes measurements, links it to harmonized metadata, and transforms them into a unified data model ready for downstream analysis. How Does Elucidata Help Mitigate These Challenges?
  4. Why Harmonize Proteomics Data on Polly? Request Demo Know More

    Make In-house and Public Proteomics Data ML-ready in a Fraction of the Time Unify and Manage Data From In-House Assays Configure Curation to Fit Your Analysis Needs Use Data You Can Trust
  5. 24x Faster Proteomics Research with PRIDE on Polly, $500K Savings.

    • A London-based therapeutics company faced a significant challenge in finding relevant proteomics datasets from the PRIDE repository, as only ~25% of these are completely annotated. • The company partnered with Elucidata to access high-quality, ML-ready proteomics data and completely annotated metadata to construct a comprehensive knowledge graph illustrating the intricate relationships and interactions between proteins in biological systems. • Elucidata employed a 3-step approach to deliver 60 high-quality proteomics datasets, each with over 10,000 samples. These datasets aligned with their inclusion criteria, ensuring that the datasets included disease labeling and all necessary information on samples. • Elucidata’s Polly Verified datasets allowed them to kickstart their research in 1 month versus 24 months, saving them over half a million dollars. Read full case-study here.