One of the most usual over-the-counter (OTC) medications are aspirin (e.g. Bayer), ibuprofen (e.g. Advil), naproxen (e.g. Aleve), and also acetaminophen (e.g. Tylenol). Advil, naproxen, and also aspirin are anti-inflammatory medications, which relieve reduced neck and back pain triggered by an inflamed nerves or muscle mass. important source