The absorption of Amoxicillin / Clavulanate worsens while taking with the drugs:


  • antacids - drugs that neutralize the acidity of the stomach;

  • aminoglycoside antibiotics;

  • laxatives;

  • glucosamine.

They increase the absorption of the combined vitamin C, and the simultaneous administration of allopurinol, NSAIDs, calcium channel blockers increases its concentration in the blood, reducing the rate of glomerular filtration in the kidneys.

Amoxicillin / Clavulanate with antibiotics with a bacteriostatic effect - macrolides, lincosamines, tetracyclines, chloramphenicol - is not prescribed simultaneously.

In the treatment of Amoxicillin + Clavulanic acid, the effectiveness of the action changes:


  • anticoagulants - increases, because of which control over blood coagulability is required;

  • oral contraceptives - reduced.

It is not recommended in the instructions for use of Amoxicillin / Clavulanate in the treatment of the drug with alcohol, as this increases the load on the liver and increases the risk of side effects.

Surgery

Surgical intervention is prescribed if, during conservative treatment, the patient's condition remains severe or worsens. As a rule, surgical correction is performed when purulent (apostemic) pyelonephritis, abscess or carbuncle of the kidney is detected.

During the operation, the surgeon restores the lumen of the ureter, excises inflammatory tissues and establishes drainages for the outflow of purulent fluid. buy augmentin If the kidney parenchyma is significantly destroyed, an operation is performed - nephrectomy.


Prevention

The main measure of prevention is the timely treatment of acute respiratory diseases.

Other preventive recommendations:


  • to give up smoking;

  • vaccination against influenza;

  • strengthening the immune system;

  • compliance with the rules of personal hygiene (which is especially true during the period of mass spread of SARS).

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