On April 7th Heartbleed was made public knowledge and so a race began to patch the internet. Those using open source software had to take a look at how their stack relied upon OpenSSL and it's sundry of related packages.
DevOps had to weigh the risks of tearing down production systems and endangering SLA's or risking customer data.
Moving forward it has changed how we test and trust software, seek out early warning and run DevOps.
At the heart of the Agile methodology is the ability to make changes to the front and backend of the system and see that code in production relatively quickly. This is in clear opposition to the rigors of compliance.