talk given at WordCampNL 2016, article + HTML slides here:
http://tomhermans.com/blog/learning-javascript-wp-rest-api-talk-wordcamp-nl
TLDR:
With the advent of the WordPress REST API many opportunities open up regarding building a site. And more importantly, decoupling your frontend from WordPress itself, making it a store or a platform for your data to communicate with with various tools, but mainly JavaScript. Consider this the tl;dr.