This presentation explores the intricacies of HTTP request smuggling, covering various topics including HTTP pipelining, CL/TE desynchronization attacks, and their impacts on vulnerabilities like reflected XSS and open redirects. It provides insights into HTTP/2 and WebSocket protocols, highlighting how desync attacks can occur even in modern implementations. Practical prevention methods are discussed, making this an essential guide for developers and security professionals aiming to defend against these stealthy attack vectors.