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Harrisons podclass EP. 98
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gimmatsu
May 01, 2023
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Harrisons podclass EP. 98
テーマ:汎血球減少
gimmatsu
May 01, 2023
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Transcript
Harrison’s podclass • 無料で聞ける英語のPodcast • 1エピソードあたり5-10分 • 症例提示、クイズ(5つの選択肢から1つ選ぶ)、解説 • AccessMedicine、McgrawHillが提供
• Host:Charles Wiener先生, Cathy Handy先生
98. 68歳女性、間欠的な発熱と盗汗 • 2週間前から倦怠感、間欠的な発熱、夜間の寝汗 • 最近の渡航歴やシックコンタクトなし • 退職した弁護士、3-13歳の3人の孫の面倒をみている • 体温
38℃、眼瞼結膜蒼白あり、他の身体所見は正常 • 血算:WBC 800 /μL, Hb 8 g/dL, Plt 98,000 /μL
最も可能性が低い診断は? A. 再生不良性貧血 B. 銅欠乏 C. 骨髄異形成症候群 D. 骨髄線維症 E.
パルボウイルス感染症
最も可能性が低い診断は? 正解:E. パルボウイルス感染症 解説:汎血球減少の原因に関する問題。薬剤歴の聴取は 必要。骨髄異形成症候群、骨髄線維症、再生不良性貧血 は汎血球減少の原因となりうる。また、銅欠乏は骨髄増 殖性疾患のmimicsとなりうる。パルボウイルス感染症 で貧血は起こりうるが汎血球減少の原因とはならない。
今回のPoint 汎血球減少の鑑別疾患は悪性腫瘍、栄養障害、感染症、 薬剤など多岐にわたる パルボウイルス感染症では汎血球減少は起こらない •Listening point 眼瞼結膜蒼白 “Pale conjunctiva”を聞き取れるか