Prematurity: lung, muscles and brain are too immature to support adequate gas exchange • Full-term babies may require intensive care (e.g. infec;on, aJer an opera;on, birth depression etc.) • We ven;late >1500 “ven;lator days” yearly • Ven;la;on is also an important part of adult intensive care
has improved significantly: 1. Synchroniza.on with the pa;ent's own breathing effort 2. Aiming for a set volume of gas (volume targe.ng) rather than using the same infla;ng pressure
are "too complex" for everyday clinical work • Most data the ven;lators are providing are not considered during clinical decision making • Ven;lator data are not rou;nely archived at a high sampling rate and not analyzed retrospec;vely
and analyse them computa;onally • To provide the clinician with SIMPLE indicators of ven;la;on and ven;lator-pa;ent interac;on • Eventually to move closer to automa;on of mechanical ven;la;on
59 ven;lated neonates • Most con;nuous recordings are >24 hours, usually 2-4 days • Data are retrieved as csv files • Generates approximately 650 Mbyte data / 24 hours of ven;la;on
fig = sns.jointplot(x="paw", y="flow", data=fast_2a, s = 5) Two-dimensional scaberplots using the seaborn library 3 hours of ven;la;on (~1,000,000 data points)