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Saving the World: Open Source and Open Science

Saving the World: Open Source and Open Science

Marcus Hanwell

October 23, 2014
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  1. Saving the World Open Source and Open Science! Dr. Marcus

    D. Hanwell @mhanwell +MarcusHanwell All Things Open 22 October, 2014
  2. Nullius in verba Motto of the Royal Society, founded in

    1660 “Take nobody’s word for it”
  3. Showing What’s Inside the Box! •  Need everything to reproduce

    results o  Raw data collected §  How it was collected, conditions, versions o  Steps to run calculations/analysis §  Often source code o  Analyzed results SHOW YOUR WORK!
  4. “Scientific research has changed the world. Now it needs to

    change itself.” Economist, http://www.economist.com/news/leaders/21588069-scientific-research-has-changed- world-now-it-needs-change-itself-how-science-goes-wrong
  5. “Publishing Research Without Data is Simply Advertising, Not Science” Graham

    Steel, http://blog.okfn.org/2013/09/03/publishing-research-without-data-is-simply-advertising-not-science/
  6. “Is the evidence for austerity based on an Excel spreadsheet

    error?” Washington Post, April 2013 http://www.washingtonpost.com/blogs/wonkblog/wp/2013/04/16/is-the-best-evidence-for-austerity- based-on-an-excel-spreadsheet-error/
  7. What is Open??? •  What does open mean, how open

    is open? o  Everyone has the same access o  No commercial, no derivatives is NOT OPEN •  Certain basic rights are granted to ALL o  Share o  Modify o  Use
  8. Only 6 out of 53 “landmark” cancer studies could be

    reproduced http://www.nature.com/nature/journal/v483/n7391/full/483531a.html
  9. Reproducibility Initiative Receives $1.3M Grant to Validate 50 Landmark Cancer

    Studies http://blog.scienceexchange.com/2013/10/reproducibility-initiative-receives-1-3m-grant-to- validate-50-landmark-cancer-studies/
  10. An Analogy: Making Beer •  I make great home brew!

    o  Using 5 gallon bioreactors to make “sweet nectar” •  I discovered a technique to make it better! o  I sing to my beer each evening as it ferments! o  My assertion is: §  It energizes the yeast, and makes sweeter beer... o  I have graphs showing 9/10 people prefer it o  Even did chemical analysis showing less esters!
  11. Do I Really Need to Share More? •  The beer

    I sang to was next to my stool o  It was in a colder part of my basement §  I didn’t want to sit for hours in the hot part! o  Yeast produce more esters when they are too hot §  They needed to be in a control group §  It didn’t matter if it got a little hotter over there •  Do I want to sell beer, or do science? REPRODUCIBILITY!
  12. GTO = ce−αr2 φi = c µi φ µ µ

    ∑ ρ r ( )= P µν φ µ φ ν ν ∑ µ ∑
  13. GTO = ce−αr2 φi = c µi φ µ µ

    ∑ ρ r ( )= P µν φ µ φ ν ν ∑ µ ∑ Data Equations Source Code
  14. Always Pushing the Boundaries •  Science is about learning new

    things •  Understanding the universe •  Communicating that understanding •  Adding to the sum of human knowledge •  It is not about o  “selling ideas” or “promoting your work”
  15. We Need Your Help! •  So many people to thank,

    so little space •  Opensource.com, Kitware •  The Open Science movement, open source, … •  Find me on the web [email protected] @mhanwell +MarcusHanwell cryos.net github.com/cryos