critical role online collaboration played in this effort. Of the seven coauthors on this paper, two I've met only once in real life, and two I've never met in person. We are spread over four cities, five organizations, and nine time zones. Initiating and executing this collaboration happened virtually entirely online, aided by the FriendFeed Life Scientists room and Molecular and Cellular Biology WikiProject at Wikipedia. It was an eye-opener in terms of how effective online collaboration can be done.