6 dem ographic values 40,336 patients sepsis label 70% missing data 2932 sepsis positive patients 8 to 336 hourly measurements 12,237 patients 28,099 patients 2064 sepsis positive patients 30% Holdout For Testing Impute Temporal Data by Linear Interpolation/ Extrapolation Balance Training Data by Undersampling Augment Temporal Data with Rates of Change Normalize and Zero-Fill 34 tem poral variables velocity acceleration Δ(X) Δ²(X) Training Set: 199,686 observations × 108 features Test Set: 469,332 observations × 108 features 19,669 sepsis positive labels