If your app needs very deep native integration, there's currently no way around GitHub's Electron. This wrapper bundles Node.js and Chromium to allow web-based applications to access all interfaces platform-specific applications can. On the other hand, there are Progressive Web Apps (PWA), that became ever more powerful over the last couple of years. While the web app gap continues to get smaller, it will never completely go away, as the trust model of the web won't allow some APIs to be made generally available. This is where Isolated Web Apps (IWA) come in. This proposal by Google could make Electron obsolete, as powerful web apps can be run right inside your browser. This is possible by an additional trust anchor: deploying your app through a store. Christian Liebel from Thinktecture shows you the different application models with their advantages and disadvantages.