Advances in Metabolomics Experiments and opportunities for Pathway and Network Analysis

Some highlights of #metsocdublin2016

Transcript

1. Advances in Metabolomics Experiments and opportunities for Pathway and Network Analysis Egon Willighagen 2016-07-07 @egonwillighagen
2. Metabolomics 2016 http://metabolomics2016.org/
3. #metsocdublin2016
4. Plenary Speaker: Jeremy Nicholson Metabolic profiling in system medicine Metabonome := the collection of species specific metabolomes creating a distance matrix for KEGG is complex mathematics Lysine as disease marker
5. Plenary Speaker: Luke O'Neill (@laoneill111) why we cherish glucose and become insuline resistant instead The intersection between inflammation and metabolism NLRP3, that has an essential role in inflammation as a sensor of pathogens mentions the 500 known cytokines Metformin to reduce inflammation succinate. Blocks PHD -> HIF-1alpha -> IL-1beta... succinate in inflamed tissue
6. Plenary Speaker: Ines Thiele Now working on AGORA to capture microbial metabolism
7. Some Speaker: Ric de Vos WP3682 by Justin van de Hooft
8. Bruker Daltonics: PathVisio logo on slides Aiko Barsch http://bruker-marketing.actonsoftware.com/acton/attachment/4047/u-00d0/0/-/-/-/-/
9. Technological advancements Waters: collision cross section: http://www.waters.com/waters/library.htm?cid=511436&lid=134743905 http://chemwiki.ucdavis.edu/Core/Physical_Chemistry/Kinetics/Modeli ng_Reaction_Kinetics/Collision_Theory/Collisional_Cross_Section
10. Pathway and Network Analysis session ~180 attendents
11. Keynote Speaker: Matt DeJongh ModelSEED https://github.com/ModelSEED
12. Plenary Speaker: Tsutomu Masujima Fujii et al. Aug. 2015. Direct metabolomics for plant cells by live single-cell mass spectrometry. Nature Protocols 10 (9), 1445-1456. http://dx.doi.org/10.1038/nprot.2015.084
13. Metabolomics Forum http://www.metabolomics-forum.com/
14. More on Lanyrd http://lanyrd.com/2016/metsocdublin2016/