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How can investors spot AI BS?

How can investors spot AI BS?

Shahid N. Shah

October 16, 2020
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  1. AI “washing” allows entrepreneurs and
    investors to cover up investment thesis
    flaws with hype and “BS”.
    How can investors spot
    AI BS?
    @ShahidNShah Publisher, www.Medigy.com

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  2. The simplest answer is:
    Can the innovator describe the
    outcome of their novelty
    without saying “ML” or “AI”?

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  3. Why?
    AI is not a product you can buy, it’s an experimentation
    technique which allows for rapidly poking and prodding at
    huge volumes of previously untapped data to discover
    facts and relationships about the complexity of our
    world.
    Rather than poking and prodding at genes, cells or
    molecules to see how they interact in labs, “data
    scientists” use ML and AI to more rapidly discover
    relationships that would be difficult for humans to “see”.

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  4. How to Spot AI BS
    An entrepreneur that says, "we use AI for drug discovery”
    is just as silly as one who says, “we experiment with
    molecules for drug discovery.” It does not mean anything.
    If someone said “you should invest in my company
    because we know how to culture bacteria" you'd look at
    them like they were delusional.
    The same should be done with entrepreneurs who use
    “AI” and “ML” as if they are the ends, rather than the
    means to the ends.

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  5. Technology has digitized our experiences
    Last and past decades
    Digitize
    mathematics &
    engineering
    Digitize maps,
    literature, news
    Digitize
    purchasing,
    social networks
    Predict crowd
    behavior
    This and future decades
    Digitize
    biology
    Digitize
    chemistry
    Digitize
    physics
    Predict human
    behavior
    Gigabytes and petabytes, all sharable Petabytes and exabytes, not shareable

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  6. AI must usher in the Scientific Method 3.0 .
    1.0
    Identify
    phenomenon
    Think about
    nature
    Fit to known
    patterns
    Guess at
    answers
    3.0
    Identify
    data
    Generate
    questions
    Mine data
    Answer
    questions
    2.0
    Identify
    problem
    Ask
    questions
    Collect
    data
    Answer
    questions

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  7. How will we know if we’ve reached 3.0 ?

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  8. 15-year-old student discovers cure for rare disease
    while gaming
    Computer creates treatment for prostate cancer

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  9. Machine Learning and AI in healthcare will be slowed by intermediated business
    models, misunderstood regulations such as HIPAA / FDA QSR and protective
    regulations such as licensure and credentialing.

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  10. Where ML and AI are applicable
    Therapies
    Therapeutic
    Tools
    Diagnostics
    Diagnostic
    Tools
    Patient
    Administration
    Payer Admin
    Clinical
    Professional
    Education
    Public Health
    Education
    Patient
    Education
    Most Regulation
    Least Regulation
    Cohort specific
    Personalized
    Risk Data Sharing

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  11. Where ML and AI are applicable
    Therapies
    Therapeutic
    Tools
    Diagnostics
    Diagnostic
    Tools
    Patient
    Administration
    Payer Admin
    Clinical
    Professional
    Education
    Public Health
    Education
    Patient
    Education
    Most Regulation
    Least Regulation
    Auto Literature Review
    Specialty-specific Content

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  12. Where ML and AI are applicable
    Therapies
    Therapeutic
    Tools
    Diagnostics
    Diagnostic
    Tools
    Patient
    Administration
    Payer Admin
    Clinical
    Professional
    Education
    Public Health
    Education
    Patient
    Education
    Most Regulation
    Least Regulation
    Auto Adjudication
    Fraud Detection
    Quality Compliance
    Contract Adherence

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  13. Where ML and AI are applicable
    Therapies
    Therapeutic
    Tools
    Diagnostics
    Diagnostic
    Tools
    Patient
    Administration
    Payer Admin
    Clinical
    Professional
    Education
    Public Health
    Education
    Patient
    Education
    Most Regulation
    Least Regulation
    Patient Self Diagnostics
    Unlicensed Pro Diagnostics
    Digitally and Heuristically Guided Diagnostics
    Images (self, guided, consulted)
    Labs and Chemistry (self, guided, consulted)
    Multi-omics (self, guided, consulted)
    Molecular Biology

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  14. Where ML and AI are applicable
    Therapies
    Therapeutic
    Tools
    Diagnostics
    Diagnostic
    Tools
    Patient
    Administration
    Payer Admin
    Clinical
    Professional
    Education
    Public Health
    Education
    Patient
    Education
    Most Regulation
    Least Regulation
    Auto Triage for Low-risk
    Augmented Triage for Higher risk
    Infection control / Anti-microbial Stewardship
    Consulted Tele Diagnostics
    Med Device Continuous Diagnostics

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  15. Where ML and AI are applicable
    Therapies
    Therapeutic
    Tools
    Diagnostics
    Diagnostic
    Tools
    Patient
    Administration
    Payer Admin
    Clinical
    Professional
    Education
    Public Health
    Education
    Patient
    Education
    Most Regulation
    Least Regulation
    Physical
    Mental (chat, VR, etc.)
    Digital (nutritional, etc.)
    Clinical Research ( “systematic review automation”)
    Drug Development
    Clinical Discovery (unattended and digital)

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  16. Where ML and AI are applicable
    Proteomics
    Genomics
    Biochemical
    Imaging
    Behavioral
    Phenotypics
    Admin
    Economics
    Connectivity Integration Transformation Comprehension Enrichment Insights Cognition
    No ML or AI possible without these

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  17. The State of AI in Life Sciences
    Find what might
    work
    Validate in silicon
    without clinical
    trials
    Validate
    effectiveness in
    the real world
    Commercialization
    Distribute safely
    and at scale
    Manufacture
    safely and at scale
    Monitor Patients
    Post Market
    Improve Safety
    Post Market
    Science 3.0 (drug
    discovery)
    VERY FAR AWAY AND
    SPECULATIVE

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  18. The State of AI in Life Sciences
    Find what might
    work
    Validate in silicon
    without clinical
    trials
    Validate
    effectiveness in
    the real world
    Commercialization
    Distribute safely
    and at scale
    Manufacture
    safely and at scale
    Monitor Patients
    Post Market
    Improve Safety
    Post Market
    Biology simulation
    VERY FAR AWAY BUT
    HAS SIGNIFICANT
    PROMISE, WORTH
    INVESTING

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  19. The State of AI in Life Sciences
    Find what might
    work
    Validate in silicon
    without clinical
    trials
    Validate
    effectiveness in
    the real world
    Commercialization
    Distribute safely
    and at scale
    Manufacture
    safely and at scale
    Monitor Patients
    Post Market
    Improve Safety
    Post Market
    Automating
    clinical trials,
    detecting fraud
    TODAY,
    ACCELERATING,
    WORTH INVESTING

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  20. The State of AI in Life Sciences
    Find what might
    work
    Validate in silicon
    without clinical
    trials
    Validate
    effectiveness in
    the real world
    Commercialization
    Distribute safely
    and at scale
    Manufacture
    safely and at scale
    Monitor
    Patients Post
    Market
    Improve Safety
    Post Market
    Biggest opportunity to learn
    from other industries
    TODAY, ACCELERATING,
    WORTH INVESTING

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  21. The State of AI in Life Sciences
    Find what might
    work
    Validate in silicon
    without clinical
    trials
    Validate
    effectiveness in
    the real world
    Commercialization
    Distribute safely
    and at scale
    Manufacture
    safely and at scale
    Monitor Patients
    Post Market
    Improve
    Safety Post
    Market
    Biggest opportunity to learn
    from other industries
    TODAY, ACCELERATING,
    WORTH INVESTING

    View Slide

  22. The State of AI in Life Sciences
    Find what might
    work
    Validate in silicon
    without clinical
    trials
    Validate
    effectiveness in
    the real world
    Commercialization
    Distribute safely
    and at scale
    Manufacture
    safely and at scale
    Monitor Patients
    Post Market
    Improve Safety
    Post Market
    The most potential for immediate
    use (great investment thesis)
    TODAY, ACCELERATING

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  23. The State of AI in Life Sciences
    Find what might
    work
    Validate in silicon
    without clinical
    trials
    Validate
    effectiveness in
    the real world
    Commercialization
    Distribute safely
    and at scale
    Manufacture
    safely and at scale
    Monitor Patients
    Post Market
    Improve Safety
    Post Market
    Many opportunities
    in “real word
    evidence”
    TODAY, ACCELERATING

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  24. The State of AI in Life Sciences
    Find what might
    work
    Validate in silicon
    without clinical
    trials
    Validate
    effectiveness in
    the real world
    Commercialization
    Distribute safely
    and at scale
    Manufacture
    safely and at scale
    Monitor Patients
    Post Market
    Improve Safety
    Post Market
    Once we have lots of
    data from real-world
    evidence efforts
    SOON

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  25. What AI is worth investing in?
    Ask innovators hard questions, like:
    • Which monumental tasks is their novel AI eliminating?
    • Which significant roles in life sciences or healthcare
    are no longer necessary because of their novel AI?
    • Can their AI speed the delivery of patient-facing
    innovations, improve post-market quality, or speed up
    regulatory approvals?
    If you think of AI as a gold rush, pick-axes and shovels are worth investing in
    if they can be shown to add to the considerable work being done by open
    source software produced by Microsoft, Google, and others.

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  26. How should machines go through medical training?
    Which medical school will have the first machine
    learning algorithm training department?

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  27. Thank You. Join the Innovation
    Evaluation Revolution at
    www.Medigy.com
    Find this and many other of my decks at
    http://www.SpeakerDeck.com/shah
    How can investors spot AI BS?
    @ShahidNShah
    [email protected]

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