Upgrade to Pro — share decks privately, control downloads, hide ads and more …

從演化的角度來剖析 COVID-19病毒變異株

從演化的角度來剖析 COVID-19病毒變異株

不同 covid-19 病毒變異株一波波的流行,它們演化之間的關聯是什麼?
Google Drive 簡報免費下載:https://reurl.cc/eXY3VR


May 01, 2023

More Decks by 蔡秀吉

Other Decks in Research


  1. Evolutionary rate: About 1.1 × 10−3 subs/site/year Size of SARS-CoV-2 genome (29.9kb)

    Which is in the same order of magnitude as other RNA viruses. Evolutionary rates of human influenza A: 1.8 × 10−3 to 2.2 × 10−3 Even lower than some kinds of flu viruses. So Nakagawa & Takayuki Miyazawa Inflammation and Regeneration volume 40, Article number: 17 (2020) Virus Evolution, Volume 6, Issue 2, July 2020, veaa061, J Virol. 2006 Apr; 80(7): 3675–3678.
  2. What difference between mutation, variant and strain? The actual change

    in sequence. E.g. CAG codon wrong nucleic acid get added to the chain (CCG) glutamine-to-proline Genomes that differ in sequence are often called variants. Variants could differ by a single or many mutations. A variant is a strain when it has a demonstrably different phenotype e.g. difference in transmissibility, virulence or antigenicity, Mutation Variant Strain