2 0 1 4 0 1 6 0 1 8 0 2 0 0 E x e rc is e T o le ra n c e o n D o u b le t C h e m o th e ra p y D a y N u m b e r o f s te p -u p s in 5 m in s First experience of chemo effect Begin Docetaxel Cancer Diagnosis Begin Doublet Chemotherapy
0 0 0 1 0 2 0 3 0 E x e rc is e T o le ra n c e o n D o c e ta x e l C h e m o th e ra p y D a y T im e e n d u rin g h ig h in te n s ity e x e rc is e (m in s ) Begin Targeted Therapy Begin Docetaxel
0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 0 2 0 4 0 6 0 8 0 M a x im u m E x e rc is e L o a d o n T a rg e te d T h e ra p y D a y T o ta l T im e (J o g & W a lk ) (m in ) Begin Targeted Therapy
0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 0 2 0 4 0 6 0 8 0 E x e rc is e T o le r a n c e o n T a rg e tte d T h e ra p y D a y L o n g e s t c o n tin u o u s jo g (m in ) Begin Targeted Therapy
0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 0 2 0 4 0 6 0 8 0 E x e rc is e T o le r a n c e o n T a rg e tte d T h e ra p y D a y L o n g e s t c o n tin u o u s jo g (m in ) Begin Targeted Therapy
0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 0 2 0 4 0 6 0 8 0 E x e rc is e T o le r a n c e o n T a rg e tte d T h e ra p y D a y L o n g e s t c o n tin u o u s jo g (m in ) Begin Targeted Therapy
1. Minimizing risk 2. Maximizing early detection 3. Wider availability of optimal treatments 4. Investment in the development of new treatments X X X