loss of sensation, usually by damage to a nerve or receptor. 2. loss of the ability to feel pain, caused by administration of a drug or other medical intervention. • Dysesthesia: 1. distortion of any sense, especially of the sense of touch. 2. an unpleasant abnormal sensation produced by normal stimuli. dysesthet'ic, adj. auditory dysesthesia • Cryesthesia • Paresthesia : numbness • Graphestesia • kinesthesia