While we constantly pay attention to new utility libraries, MVC frameworks, and other well-publicised tools, most of our non-library coding hasn’t changed since ES3.
We’re missing out: beyond the obvious, there’s a world of interesting stuff you can and should be doing with ES5: safe extension of inbuilt methods, mechanisms for live binding data and DOM, and a whole host of techniques to make your code shorter and more readable. Best of all, it’s already built into your browser and node.