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Panel on VIVO Use-Cases for Collaborative Scien...

Panel on VIVO Use-Cases for Collaborative Science - Barnett Slides

These are the slides from Bill Barnett's talk at the #VIVO13 Conference entitled "VIVO Use-Cases for Collaborative Science: From Researcher Networks to Semantic User Interfaces for Data." This conference was held in St. Louis, MO on August 15-16, 2013.

Robert H. McDonald

August 15, 2013
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  1. NCATS Clinical and Translational Science Awards •  The CTSA program

    in the NCATS Division of Clinical Innovation supports a national consortium of medical research institutions that work together to improve the way clinical and translational research is conducted nationwide to enhance its efficiency and quality. Its goals are to accelerate the process of translating laboratory discoveries into treatments for patients, to engage communities in clinical research efforts, and to train a new generation of clinical and translational researchers. http://www.ncats.nih.gov/research/cts/ctsa/ctsa.html
  2. CTSA Strategic Goal Committee 3: Enhancing Consortium-Wide Collaborations •  Facilitating

    networks and collaborations of investigators (finding the right people) •  Facilitate investigators' ability to locate equipment and resources •  Promote and Enhance Collaboration Done: Research Networking Recommendations, including VIVO and Eagle-I ADOPTED https://ctsacentral.org/committee/sg3-enhancing-consortium-wide-collaborations
  3. …so VIVO has been adopted as the standard across CTSAs

    and CTSAs have been tasked with advocating the implementation of Research Networking systems. Are we done? Are we ‘Research Institutions that work together’?
  4. CTSA Productivity so far 11,252 publications cite CTSA funding https://www.ctsacentral.org/reports/scientificdiversity

    on August 8, 2013 Around 600 cite multiple grants that indicate multiple institutions collaborating (for the most part)
  5. NCATS CTSA RFA-TR-12-006: Relevant Specific Objectives •  Provide resources and

    services to support and speed the planning and implementation of clinical and translational research across the entire range of research and communities •  Facilitate the training and career development of a robust translational research workforce http://www.ncats.nih.gov/research/cts/ctsa/funding/apply/tr-12-006.html
  6. NCATS CTSA RFA-TR-12-006: Possible Examples of Programs •  Multi-site collaboration,

    including expertise in global health •  Practical trials in health care settings •  Programs developing innovative models for patient and community engagement in research http://www.ncats.nih.gov/research/cts/ctsa/funding/apply/tr-12-006.html
  7. NCATS CTSA RFA-TR-12-006: also… •  The Institutional CTSA Program focuses

    on interdisciplinary translational research needs by integrating clinical and translational science across multiple departments, schools, and clinical research institutes representing a team science approach to research collaboration among institutional partners. http://www.ncats.nih.gov/research/cts/ctsa/funding/apply/tr-12-006.html
  8. 2013 IOM Report: “The Challenge for the next phase of

    the CTSA Program will be to establish a more integrated and collaborative national network that will further catalyze the development of new diagnostics, therapeutics, and preventative interventions while driving innovation in clinical and translational research methods, processes, tools, and resources and leveraging the ever-expanding capabilities of health informatics tools and other research technologies.” http://www.iom.edu/Reports/2013/The-CTSA-Program-at-NIH-Opportunities-for- Advancing-Clinical-and-Translational-Research.aspx
  9. Austin Reply to: 2013 IOM Report Recommendations “The recommendation to

    increase substantive collaboration across and beyond the CTSA Consortium is vital to realizing the system-wide changes that are needed in clinical and translational research.” http://www.ncats.nih.gov/research/cts/ctsa/about/iom/iom.html
  10. What are the implied CTSA Use Cases for VIVO? That

    someone would actually pay money for? •  Innovate translational research •  Education and workforce development •  Develop new products and therapies •  Improve multi-site clinical trials teams •  Improve community engaged research
  11. What is going on to advance these use cases? -

    Institutionally 1.  75% of CTSAs have Research Networking (RN) systems 2.  Many RN systems now support: •  person and topic search, •  co-authorship, network, and concept mapping, •  CV generation, •  Linked Open Data RDF stores,
  12. What is going on to advance these use cases? -

    Nationally 1.  Integrated Semantic Framework (CTSAConnect) to integrate VIVO and Eagle-I ontologies 2.  FutureResearchNet Cross-Institutional Search (Direct2Experts, VIVOSearch, CTSASearch, C- IKNOW) – upcoming pilot testing
  13. What should the VIVO Community do? TO Innovate translational research

    •  Better support for administrative processes, •  applications that support formation of teams, •  grant prospecting, •  trend prospecting,
  14. What should the VIVO Community do? FOR Education and workforce

    development •  Develop applications that support mentoring, •  created topic based virtual cohorts, •  student team formation, etc.
  15. What should the VIVO Community do? TO Develop new products

    and therapies •  Improve ability to matchmake with industry partners. Example: i2iconnect.org •  establish pre-competitive collaboration zones for product development.
  16. What should the VIVO Community do? TO Improve multi-site clinical

    trials teams •  More rapid identification of research partners for clinical trials, •  automatic matching and recommendation of researchers for clinical trials and visa versa. •  Support mechanism for pragmatic trials.
  17. What should the VIVO Community do? TO Improve community engaged

    research •  Creation of community partner VIVOs, •  matchmake among researchers, community groups, and research topics.
  18. Thanks to the following folks for their help with this

    presentation: •  Dave Eichmann, Iowa •  Firas Wehbe, Vanderbilt/CTSA Coordinating Center •  Sarah Stallings, Vanderbilt/CTSA Coordinating Center