Upgrade to Pro — share decks privately, control downloads, hide ads and more …

Moden epidemiology Chap.26 Social Epidemiology

Yurika Kawazoe
January 14, 2020

Moden epidemiology Chap.26 Social Epidemiology

Yurika Kawazoe

January 14, 2020
Tweet

More Decks by Yurika Kawazoe

Other Decks in Science

Transcript

  1. Causation and Confounding in Social Epidemiology Exposure and Covariate Assessment

    in Social Epidemiology • Social Factors Defined and Measured at the Individual Level • Social Factors Defined and Measured at the Aggregate Level Analytic Approaches • Multilevel Modeling • Marginal Models • Effect Decomposition • Life-Course SES Concepts • Experiments and Quasi-Experiments • Narrative Historical Approach Chapter26 Social Epidemiology Jay S. Kaufman P.532〜 P.532 2
  2. Introduction P.532〜 .PEFSOFQJͰ͸ʜ lूஂʹ͓͚ΔࣾձతཁҼͱ࣬ױͱͷؔ܎Λݚڀ͢Δ͜ͱͰ͋Δz ΠνϩʔɾΧϫνઌੜͷஶॻͰ͸ʜ l݈߁ঢ়ଶͷࣾձతͳ෼෍͓Αͼ݈߁ͷࣾձతܾఆཁҼΛݚڀ͢ΔӸֶͷҰ෼໺l Berkman, L. F., Kawachi,

    I., & Glymour, M. M. (Eds.). (2014). Social epidemiology. Oxford University Press. ࣾձӸֶͷఆٛ ࣾձӸֶͷಛ௃ • ࣾձతʹఆٛ͞Ε͍͔ͨͭ͘ͷଆ໘ʢਓछຽ଒ੑɼδΣϯμʔɼࣾձܦࡁత ֊ڃ஍Ґʣͷ͍ͣΕ͔ʹैͬͯ෼ྨ͞ΕͨάϧʔϓؒͰɼ͋ΒΏΔϦεΫҼࢠ·ͨ͸ ݈߁্ͷΞ΢τΧϜͷҟͳΔൃੜΛแؚ͢ΔΑ͏ʹ޿͘ղऍ͢Δ • മ࿐ͷఆٛ·ͨ͸෼ੳϞσϧʹࣾձతɼܦࡁతɼจԽతͳม਺Λ໌ࣔతʹؚΊΔ͔ɼ ղऍʹࣾձՊֶཧ࿦Λ໌ࣔతʹࢀর͢Δ • ࣾձత֊૚Խɼ౎ࢢԽɼ২ຽ஍ओٛͳͲͷࣾձཧ࿦·ͨ͸ࣾձ࢙ύϥμΠϜͷจ຺Ͱ ղऍ͢Δ͜ͱ͕Ͱ͖Δ 3
  3. Introduction P.532〜 ҰൠతͳӸֶ׆ಈ͸࣍ͷͭͷλΠϓʹ෼ྨ͞ΕΔ αʔϕΠϥϯε පҼֶతਪ࿦ • ఆٛ͞Εͨമ࿐ͱ0VUDPNFͷؒͷҼՌؔ܎Λཧղ͠Α͏ͱ͢Δ • ࣮ࣾձͰ͸ͳ͘ɼ͋Δఆٛ͞ΕͨԾ૝తͳհೖͷ΋ͱͰͷมԽΛࣔ͢Α͏ͳσβΠϯ ྫʣߴྸऀͷࢮ๢ϦεΫʹର͢Δ෋ͷมԽͷҼՌޮՌΛਪఆ

    • ࣾձ͕ͲͷΑ͏ʹݟ͑Δ͔Λਖ਼֬ʹදݱ͠Α͏ͱ͢Δ • ؔ৺ͷ͋ΔӸֶత਺஋͸ɼҰൠʹҼՌޮՌΑΓ΋༗ප཰΍ൃੜ཰Ͱ͋Δ • ಛఆͷമ࿐ʹؔ܎ͳ͘ɼ࣌ؒɼ೥ྸɼࣾձ֊ڃͳͲͷई౓ʹؔ࿈ͨ͠0VUDPNFͷ ൃੜʹয఺Λ౰ͯΔ ྫʣਓछ͓Αͼࣾձ֊ڃʹΑΔףಈ຺࣬ױͷ෼෍ 4
  4. Causation and Confounding in Social Epidemiology Exposure and Covariate Assessment

    in Social Epidemiology • Social Factors Defined and Measured at the Individual Level • Social Factors Defined and Measured at the Aggregate Level Analytic Approaches • Multilevel Modeling • Marginal Models • Effect Decomposition • Life-Course SES Concepts • Experiments and Quasi-Experiments • Narrative Historical Approach Chapter26 Social Epidemiology Jay S. Kaufman 5
  5. Causation and Confounding in Social Epidemiology P.533〜 ݪҼͱͯ͠ͷݕ౼͔Βআ֎͠ͳ͚Ε͹ͳΒͳ͍ • ࣾձӸֶతݚڀʹ͓͍ͯɼਓछຽ଒ɾੑผ͕༗ޮͳয఺Ͱͳ͍༁Ͱ͸ͳ͍

    • ݚڀσβΠϯ͓Αͼ෼ੳతΞϓϩʔν͕മ࿐͓ΑͼԾઆతհೖͷ࣮࣭తʹ ҙຯͷ͋Δ֓೦ԽʹରԠ͠ͳ͚Ε͹ͳΒͳ͍ ݪҼ ݁Ռ ਓछຽ଒ ҩࢣͷ਍அ ਓछຽ଒ ףಈ຺࣬ױൃ঱ϦεΫ ࣮ࡍͷ࣮ݧ·ͨ͸૝૾্ͷ࣮ݧͰ෺ཧతʹૢ࡞Ͱ͖Δ հೖ͢Δ͜ͱʹ໌നͳҙຯ͸ͳ͍ɼհೖ͢Δ͜ͱ͸ෆՄ Өڹ͋Γ Өڹͳ͠ ૢ࡞ෆՄೳͳҼࢠʢਓछຽ଒ɾੑผͳͲʣ 7
  6. Causation and Confounding in Social Epidemiology P.533〜 • ࣾձత૚ผԽ΍ݸਓͷҙࢥͷෳࡶͳ૬ޓ࡞༻ʹىҼ͢Δ •

    ॴಘิॿɼڭҭϩʔϯɼॅ୐ࢧԉͷ੓෎ϓϩάϥϜͳͲͰम০͞ΕΔՄೳੑ͕͋Δ • ඪຊूஂʹ͓͚Δമ࿐ϨϕϧΛݻఆ͢Δ༷ʑͳհೖͷ΋ͱɼ0VUDPNFͷ෼෍ͷൺֱʹ පҼతؔ৺͕͋Δ ૢ࡞ՄೳͳҼࢠʢॴಘɾڭҭɾॅډͷ࣭ͳͲʣ ݪҼ ݁Ռ ॅډλΠϓ ᄶଉൃ࡞ ެӦॅ୐ ݸਓॅ୐ 74 മ࿐ϨϕϧΛ ݻఆ͢Δհೖ 0VUDPNFͷ ൺֱ 9
  7. Causation and Confounding in Social Epidemiology P.533〜 ؔ࿈ "TTPDJBUJPO ޮՌ

    &GGFDU WT WT ޮՌͱؔ࿈ͷ͕ࠩަབྷʢ$POGPVOEJOHʣ EPͱهࡌ͢Δຊ΋͋Γ·͢ 11
  8. Causation and Confounding in Social Epidemiology P.533〜 ݪҼ ݁Ռ ॅډλΠϓ

    ᄶଉൃ࡞ ශࠔ • ؍ଌσʔλͷ໰୊ͷ֩৺͸ݸମ܈ͷઃఆʢset/doʣΛߦ͏͜ͱ͕Ͱ͖ͳ͍͜ͱ • ҼՌޮՌΛΑΓ༗ޮʹਪఆ͢ΔͨΊʹ͸ɼ؍ଌ͞ΕͨσʔλΛԿΒ͔ͷํ๏Λ༻͍ͯ ௐ੔͢Δඞཁ͕͋Δ ॅډλΠϓ͕ᄶଉൃ࡞ʹ༩͑ΔӨڹΛݕ౼ͨ͠৔߹ɼශࠔ͕ަབྷҼࢠͱͯ͠ߟ͑ΒΕΔ ශࠔͷଞͷ෺࣭త·ͨ͸৺ཧࣾձతൃݱʹର͢ΔͦΕΒͷ૬ޓ൓Ԡ͔Βަབྷ͕ੜ͡Δ Մೳੑ΋͋Δ ަབྷҼࢠ • ෺࣭తཁҼ • ৺ཧࣾձతͳཁҼ • ͦΕΒͷ૬ޓ൓Ԡ 12
  9. Causation and Confounding in Social Epidemiology P.533〜 ަབྷҼࢠͷௐ੔ํ๏ʹ͍ͭͯ ͭ͸ଌఆ͞Εͨශࠔঢ়ଶΛ৚݅ʹ͢Δ͜ͱ ශࠔঢ়ଶΛTUSBUJGJDBUJPOWBSJBCMFʹ͢Δʢྫɿශࠔ૚ͱඇශࠔ૚

    ශࠔ૚ͱඇශࠔ૚ʹ෼͚ͯղੳ͢Δ͜ͱͰަབྷҼࢠʢශࠔঢ়ଶʣͷӨڹΛऔΓআ͘ ˠമ࿐ͱ0VUDPNFͷҰൠతͳݪҼΛྻڍ͠ɼਖ਼֬ʹଌఆ͕Ͱ͖ͨ৔߹ɼ ͜ͷํ๏͸؍࡯σʔλ͔Β๬·͍͠ҼՌޮՌΛಛఆ͢Δͷʹे෼Ͱ͋Δ ͔͠͠ɼࣾձతമ࿐ʹରͯ͠͸ࠔ೉࡞ۀͰ͋Γɼඞͣ͠΋ظ଴Ͱ͖ͳ͍ ʢཧ༝ʣ • ଟҼࢠ࣬ױͷసؼ͓Αͼॅډબ୒ͳͲͷෳࡶͳߦಈʹڞ௨͢ΔݪҼͷྻڍ͓Αͼਖ਼֬ ͳଌఆ͸ࠔ೉Ͱ͋Δ • ࢧ഑తͳܦࡁతɾࣾձతΠϯϓοτΛ൐͏ߦಈ͸ɼࣾձՊֶʹ͓͍ͯϞσϧԽ͢Δͷ͕ ඇৗʹ೉͍͜͠ͱ͕ূ໌͞Ε͍ͯΔ • ͢΂ͯͷཁҼ͕Θ͔͍ͬͯͯ΋ɼ࣮ࡍͷσʔληοτͰ͜ΕΒͷଟ͘ͷม਺Λਖ਼֬ʹ ଌఆ͢Δͷ͸େมͳ࡞ۀ 13
  10. Causation and Confounding in Social Epidemiology Exposure and Covariate Assessment

    in Social Epidemiology • Social Factors Defined and Measured at the Individual Level • Social Factors Defined and Measured at the Aggregate Level Analytic Approaches • Multilevel Modeling • Marginal Models • Effect Decomposition • Life-Course SES Concepts • Experiments and Quasi-Experiments • Narrative Historical Approach Chapter26 Social Epidemiology Jay S. Kaufman 14
  11. • ࣾձӸֶ͸ओͱͯ͠ௐࠪ͞ΕΔമ࿐ͷੑ࣭ʹΑͬͯಛ௃͚ͮΒΕΔ • മ࿐ͱڞมྔΛఆٛ͠ଌఆ͢Δٕज़͸ࣾձӸֶతํ๏࿦ͷओཁͳཁૉͰ͋Δ • ଟ͘ͷݚڀͰ͸ɼࣾձతࠩผͷओཁͳ࣠ʢਓछɾຽ଒ɼੑผɼࣾձత֊ڃɾ஍Ґʣʹ ԿΒ͔ͷܗͰؔ࿈ͨ͠മ࿐Λݕ౼͍ͯ͠Δ • ͦͷଞͷݚڀͰ͸ɼଟ͘ͷࣾձӸֶతമ࿐͕ఆٛ͞Εݕ౼͞Ε͍ͯΔ •

    ݸਓϨϕϧʢ഑ۮऀͷ༗ແɼ෺త૕ࣦɼࣾձతࢧԉɼ·ͨ͸஍ҐͷෆҰகͳͲʣ • ूஂϨϕϧʢࣾձωοτϫʔΫɼܦࡁతෆฏ౳ɼࣾձࢿຊɼۙྡॅຽͷണୣͳͲʣ • ڻ͘΂͖਺ͷമ࿐͕ߟྀ͞Ε͍ͯΔ͚ͩͰͳ͘ɼ͜ΕΒͷଟ͘͸ɼ͞·͟·ͳݚڀʹ ͓͍ͯҟͳΔํ๏Ͱఆٛ͞ΕɼධՁ͞Ε͍ͯΔ Exposure and Covariate Assessment in Social Epidemiology മ࿐ͱڞมྔධՁ P.534〜 15
  12. • Race/Ethnicity • Sex/Gender • Educational Attainment • Annual Individual

    or Family Income • Household Wealth • Occupation/Unemployment • Discrimination and Racism Exposure and Covariate Assessment in Social Epidemiology Social Factors Defined and Measured at the Individual Level P.534〜 16
  13. Exposure and Covariate Assessment in Social Epidemiology Race/Ethnicity • ݸਓత͓ΑͼࣾձతΞΠσϯςΟςΟͷத৺Ͱ͋Γɼ෺࣭త͓Αͼࣾձత஍Ґͷॏཁͳ

    ܾఆҼࢠͱͯ͠ͷ໾ׂΛՌͨ͢ • ࣾձతωοτϫʔΫɼډॅύλʔϯ͓ΑͼߦಈʹӨڹΛٴ΅͢ • ද޲͖͸૆ઌ͓Αͼ਎ମతಛ௃ͷ؍఺͔Βࢦఆ͞ΕΔ͕ɼ࠷ऴతʹʮΰʔϧυελϯ μʔυʯධՁ͕ࣗݾใࠂʹجͮ͘͜ͱΛҙຯ͢Δ • %/"ͷߴ౓ʹՄมతͳྖҬͷ෼ੳ͸ࣾձӸֶతͳؔ৺ࣄͰ͸ͳ͍ • ΧςΰϦʔԽͱͦͷ؅ཧͷܧଓతͳਐԽ͸ͦΕࣗମ͕ํ๏࿦తటপ • ࠷ۙͰ͸ɼͭͷجຊతਓछΧςΰϦʔʢΞϝϦΧΠϯσΟΞϯͱΞϥεΧݪॅຽɼ ΞδΞܥɼࠇਓͱΞϑϦΧܥΞϝϦΧਓɼϋϫΠݪॅຽͱଞͷଠฏ༸ॾౡॅຽɼനਓɼ ͦͷଞͷϨʔεʣͷͷՄೳͳ૊Έ߹Θͤʹͭͳ͕ͬͨɽ • ݸਓ͸ࣗ෼ͷຽ଒ੑΛώεύχοΫ·ͨ͸ඇώεύχοΫͱఆٛ͢Δ͜ͱ͕Ͱ͖Δ P.534〜 17
  14. Exposure and Covariate Assessment in Social Epidemiology Sex/Gender • 4FY͸ɼ͢΂ͯͷਓؒࣾձʹ͓͚Δࣾձతɼ؀ڥత͓Αͼ෺࣭తঢ়گͷॏཁͳܾఆҼࢠ

    ͱͯ͠ͷ໾ׂΛՌͨ͢ • ڞมྔɼޮՌई౓म০ࢠɼ·ͨ͸૚ผม਺ͱͯ͠ͷࣾձӸֶత෼ੳʹ͓͚Δॏཁͳม਺ • (FOEFS͸ɼੜ෺ֶతͳੑͷࣾձత࣮ݱͰ͋Γɼද޲͖͸Ҩ఻ࢠܕͱදݱܕͷܗ࣭ͷ ؍఺͔Βࢦఆ͞Ε͍ͯΔ • ͦͷࣾձతҙຯ߹͍͸จԽʹେ͖͘ґଘ͍ͯ͠ΔͨΊ࣌ؒͱ৔ॴʹΑͬͯେ͖͘ҟͳΔ • ੜཧֶͱߦಈʹ͓͚Δ࣮࣭తͳࣗવมಈੑͷཧ࿦తݚڀͱೝࣝͷ૿Ճ͸ɼ͜ͷݫີͳ ೋ߲෼ྨ͕ྺ࢙త׳शʹ༝དྷ͢ΔศརͳϑΟΫγϣϯͰ͋Δͱ͍͏ೝࣝΛߴΊͨ P.535〜 18
  15. Exposure and Covariate Assessment in Social Epidemiology • ࠷΋ݹ͘Ұൠతʹ࢖༻͞ΕΔࣾձӸֶతྔͷͭ •

    ֶྺ͸ࣾձత஍Ґͷ֫ಘͷϝΧχζϜͱͯ͠΋࣮࣭తͳؔ࿈ੑΛ࣋ͭͨΊɼ ॴಘ΍෋ͷ༧ଌྗ͕ߴ͍ ܽ఺ • యܕతͳڭҭਫ४΍ɼͦͷ݁Ռͱͯ͠ੜ͡Δܦࡁతɾࣾձతศӹ͸࣌ؒͷܦաͱͱ΋ʹ มԽ͍ͯ͠ΔͨΊɼ೥ྸͷίϗʔτؒ΍஍Ҭؒͷൺֱ͸ࠔ೉ • ֶҐ΍ࢿ֨ͷऔಘʹ൐͏ڭҭن໛ͷෆ࿈ଓੑ΋಺ࡏ ྫʣߴߍΛ೥ੜҎ্Ͱଔۀͯ͠΋ࣾձతͳར఺͸΄ͱΜͲͳ͍͔΋͠Εͳ͍͕ɼ ೥ੜҎ্Ͱଔۀ͢Δͱେ͖ͳར఺͕ಘΒΕΔ͔΋͠Εͳ͍ ڭҭ಺༰ͱֶߍڭҭ೥਺ͱͷؒͷؔ܎͕ෆ࣮֬Ͱ͋Δ͜ͱɼ͓Αͼڭҭमྃͷࣾձܦࡁత ॏཁੑ͕ѹ౗తͰ͋Δ͜ͱΛߟ͑Δͱɼڭҭमྃ೥਺ʹΑΔଟ͘ͷ݈߁্ͷΞ΢τΧϜͰ ؍࡯͞ΕΔ౳ڃผؔ܎͸ɼՈఉࢿݯɼͦͷଞͷਓ͓֨Αͼ؀ڥҼࢠͷؔ਺ͱͯ͠ͷֶߍڭ ҭ೥਺ͷ಺ҼੑׂΓ౰ͯͷূڌͱղऍͰ͖Δ Educational Attainment P.535〜 19
  16. Exposure and Covariate Assessment in Social Epidemiology • ݈߁͕ࢢ৔ܦࡁͰ͸ඞध඼Ͱ͋Δͱ͍͏໌നͳཧ༝ͷͨΊɼࣾձӸֶత෼ੳʹ ͓͍ͯॏཁͳม਺

    • ࡒ੓ࢿݯ͸݈߁݁ՌʹҼՌޮՌΛ࣋ͭ͜ͱ͕࿦ཧతʹظ଴͞ΕΔ • ೥ؒݸਓॴಘ͸ڭҭͱಉ༷ʹɼࣾձత஍Ґͷහײͳࢦඪͱͯ͠ػೳ • ॴಘ͸ʮٯҼՌؔ܎ʯʹࠨӈ͞Ε΍͘͢ͳΔɻ ॴಘ͕௿͍ͱ݈߁ঢ়ଶ͕ѱԽ͢Δ ⁶ ݈߁ঢ়ଶ͕ѱԽ͢Δͱॴಘ͕௿Լ͢Δ Annual Individual or Family Income(1) P.535〜 20
  17. Exposure and Covariate Assessment in Social Epidemiology • ݸਓॴಘͰ͸ͳ͘ੈଳॴಘΛධՁ͢Δ͜ͱ͕ҰൠతʹߦΘΕ͍ͯΔ ؔ࿈͢Δ֓೦

    ශࠔ • جຊతͳ෺࣭తχʔζΛຬ͚ͨͩ͢ͷऩೖ͕ͳ͍ঢ়ଶ • ඃැཆऀΛҡ࣋͢ΔͨΊʹ࠷௿ݶඞཁͳॴಘ͸Կ͔ͱ͍͏ධՁʹج͍ͮͯੈଳॴಘΛ ශࠔϥΠϯͰೋ෼͢Δ Annual Individual or Family Income(2) P.535〜 21
  18. Exposure and Covariate Assessment in Social Epidemiology • ࢿݯͷ஝ੵΛද͢ •

    ୡ੒͞Εͨࣾձత஍Ґͷࢦඪͱ͚ͯͩ͠Ͱͳ͘ɼ݈߁ͱ෱ࢱͷαʔϏεʹಈһͰ͖Δ ૯ࢿݯͷई౓ͱͯ͠΋݈߁੒Ռʹؔ࿈ੑ͕͋Δ • ॴಘͱ෋ͷؒͷෆۉߧ͸ɼஉঁΛൺֱͨ͠৔߹ɼ·ͨ͸ਓछຽ଒άϧʔϓΛൺֱͨ͠ ৔߹ʹಛʹݦஶ ྫʣਓछຽ଒άϧʔϓؒͰ݁ՌϦεΫΛରൺ͢ΔϞσϧͰ͸ɼࣾձత஍ҐΛࣔ͢ॴಘ ͱڭҭ͕ަབྷҼࢠͱͳΔͨΊɼௐ੔͕ඞཁ • ࢿ࢈͸༷ʑͳۚ༥঎඼ʢגࣜɼ࠴݊ɼୀ৬೥ۚޱ࠲ʣ΍෺తϦϙδτϦʢՈɼ৐Γ෺ɼ ๅੴʣʹଘࡏ͢Δ͕ɼถࠃͰ࠷΋෋ͷ͋Δ΋ͷ͸ෆಈ࢈΍ं྆ͷՁ஋Ͱอ༗͞Ε͍ͯΔ • ʮՈΛ͍࣋ͬͯ·͔͢ʯͷΑ͏ͳ୯७ͳ࣭໰͸ɼࢿ࢈ਫ४ͷ௿͞ͱߴ͞Λ۠ผ͢Δͷʹ ඇৗʹ༗ӹͰ͋Δ Household Wealth P.536〜 22
  19. Exposure and Covariate Assessment in Social Epidemiology • ྺ࢙తʹॏཁͳࢦඪͷ̍ͭ •

    ࣾձతҖ৴ɼڭҭ͓Αͼࣾձతͭͳ͕Γͷػೳత݁ՌΛ͚ࣔͩ͢Ͱͳ͘ɼ৬৔ࣗମͷ ਎ମత͓Αͼ৺ཧత؀ڥΛ௨݈ͨ͡߁ʹؔ࿈͢Δঢ়گͷ௚઀తͳ൓ө΋ఏڙ͢Δ • ӳࠃΛ͸͡Ίͱ͢Δଟ͘ͷࠃͰ͸ɼඪ४తͳࣾձܦࡁత஍Ґͷई౓͸ɼถࠃͰ༏੎ͳ ڭҭ͓Αͼॴಘͷई౓ͱ͸ରরతʹɼ৬ۀ֊ڃʹج͍͍ͮͯΔ • ॴಘͱಉ༷ʹɼ৬ۀͱޏ༻ঢ়ଶ͸ੜ֔Λ௨ͯ͡ಈతͰ͋ΔͨΊɼ͜ΕΒͷાஔ͸݈߁ͷ ௿Լ͕৬ۀతҖ৴ͷ௿Լʹͭͳ͕ΔʮٯҼՌؔ܎ʯΛؚΊɼ͜ͷજࡏతͳෆ҆ఆੑͷ௕ ॴͱ୹ॴΛڞ༗͍ͯ͠Δ • ৬ۀʹ͍ͭͯͷ໌֬ͳ֓೦ͷͭ͸ਓʑͷάϧʔϓؒͷܦࡁతؔ܎ͷࢦඪͱͯ͠Ͱ͋Δ Occupation/Unemployment P.537〜 23
  20. Exposure and Covariate Assessment in Social Epidemiology • ਓछຽ଒ɼੑผɼੑతࢦ޲ͳͲͷݸਓతΞΠσϯςΟςΟͷଆ໘͸ɼެऺӴੜ্ͷ հೖʹΑͬͯૢ࡞͢Δ͜ͱ͸Ͱ͖ͳ͍͕ɼࣾձతϥϕϧͱͯ͠ͷ͜ΕΒͷΧςΰϦʔͷ

    ݁Ռ͸ॱԠՄೳͰ͋Γɼલड़ͷҙຯͰͷമ࿐ͱͯ͠ҼՌతҙຯΛ࣋ͭ • ॏཁͳҧ͍͸ɼݪҼͱͳΔม਺͸ݸਓͦͷ΋ͷͷΞΠσϯςΟςΟͰ͸ͳ͘ɼଞऀʹΑ ΔΞΠσϯςΟςΟͷೝࣝͰ͋Γɼ͜ͷೝ͕ࣝݸਓͷߦಈ΍ݸਓ͕ૺ۰͢Δ੍౓ʹӨڹ Λ༩͑ΔࡍʹՌͨ͢໾ׂͰ͋Δͱ͍͏͜ͱͰ͋Δ • Ξϓϩʔν ଟ͘ͷ৔߹ɼରਓతͳ෠ৱͱೝࣝ͞Εͨෆਖ਼ٛͷܦݧͷࣗݾใࠂʹয఺Λ౰͍ͯͯΔ • Ξϓϩʔν ࣮ݧత·ͨ͸४࣮ݧతͳσβΠϯΛ༻͍ͯݸਓ·ͨ͸૊৫ͷϓϩηεͷҙࢥܾఆʹ ର͢Δೝࣝ͞ΕͨΞΠσϯςΟςΟͷӨڹΛ෼཭͢Δ Discrimination and Racism(1) P.537〜 24
  21. Exposure and Covariate Assessment in Social Epidemiology • ྫ͑͹ɼ֎Պखज़΁ͷ঺հ΍ޏ༻΁ͷਃ੥ͷΑ͏ͳҩֶత·ͨ͸ܦࡁతͳૺ۰ͷʮ؂ࠪ ௐࠪʯ͸ɼܾఆաఔʹٴ΅͢ೝࣝ͞ΕͨूஂͷҰһͰ͋Δ͜ͱͷҼՌؔ܎Λ෼཭͢Δͨ

    Ίʹɼؔ৺ͷ͋ΔࣾձతΧςΰϦʔʢ௨ৗਓछ΍ੑผʣΛআ͍ͯɼݸਓͷಛ௃ʹ͍ͭͯ Ұகͨ͠ʢ؍ଌత·ͨ͸࣮ݧతʹʣ঱ྫͷൺֱΛؚΉɽ • ࣮ࡍͷඃݧऀΛ؍࡯͞Εͨڞมྔ্ͰϚονϯάͤ͞Δͱɼෆۉߧ͕ະଌఆଐੑʹ࣋ଓ ͢ΔՄೳੑ͕͋Δ • ࣮ࡍͷඃݧऀͷ୅ΘΓʹߦҝऀ͕༻͍ΒΕͨ৔߹ɼ͋Δ͍͸ࣄྫͷࣸਅ΍Χϧςɼٻਓ ථ͕άϧʔϓࣝผࢠΛআ͍ͯ׬શʹಉҰͰ͋ΔΑ͏ʹਓҝతʹ࡞੒͞Εͨ৔߹ɼҼՌࣝ ผޮՌ͸௚઀తʹࣝผՄೳͰ͋Δ Discrimination and Racism(2) P.537〜 25
  22. Exposure and Covariate Assessment in Social Epidemiology • ࣾձӸֶʹ͓͚Δଟ͘ͷॏཁͳม਺͸ɼݸਓ·ͨ͸ੈଳϨϕϧͰ͸ͳ͘ɼΑΓେ͖ͳ ू߹ͷϨϕϧʢ஍Ҭɼ܊ɼभ·ͨ͸ࠃʣͰఆٛ͞ΕΔ

    • Կ͕஍ҬΛߏ੒͢Δ͔ͷӡ༻্ͷఆٛ͸ఆ͔Ͱ͸ͳ͍͕ɼಛʹʮ஍Ҭʯ͸ࣾձӸֶʹ ͓͍ͯ௕೥ͷؔ৺͕ڧ͍ • ݸਓͷू߹ମΛಛ௃෇͚ΔͨΊʹ͸ɼ೔ৗతͳࠃ੎ௐࠪσʔλʹසൟʹґଘ͢ΔͨΊɼ ߦ੓۠ը͸ɼॅຽʹ͸Ұൠతʹ஌ΒΕ͍ͯͳͯ͘΋ɼ࠷΋޿͘࢖༻͞Ε͍ͯΔ஍Ҭڥք ͷ୅ସखஈͰ͋Δ Social Factors Defined and Measured at the Aggregate Level P.538〜 • Deprivation • Segregation • Inequality • Social Capital 26
  23. Exposure and Covariate Assessment in Social Epidemiology Deprivation • ݸਓͱੈଳͷ෺࣭తࢿݯ͕൴ΒͷࣾձܦࡁతҐஔΛಛ௃͚ͮΔͷͱಉ༷ʹɼ஍Ҭͷ෺࣭

    తࢿݯ͸ίϛϡχςΟͷශࠔͷఔ౓Λಛ௃͚ͮΔͷʹ࢖ΘΕΔ • ฏۉॴಘ·ͨ͸ฏۉڭҭϨϕϧͳͲͷݸਓϨϕϧͷσʔλͷू߹Ͱ͋ͬͯ΋Α͍ • ਓޱີ౓ɼ਍ྍॴ·ͨ͸าಓͷଘࡏɼյΕͨ૭·ͨ͸མॻ͖ͷීٴ཰ɼʮࣾձతແட ংʯ·ͨ͸ʮ஍ҬޮྗײʯͳͲͷԿΒ͔ͷཁ໿ྔͷେ͖͞ͳͲɼ஍ҬϨϕϧͰͷΈఆٛ ͞ΕΔࢿݯͰ͋ͬͯ΋Α͍ • ଟ਺ͷࣾձతม਺͔Βཁ໿είΞΛ࡞੒͢Δ৔߹ɼཁૉྔͷॏΈΛݟ͚ͭΔͨΊʹҼࢠ ෼ੳ๏·ͨ͸જࡏม਺๏͕༻͍ΒΕΔ • λ΢ϯθϯτ͓ΑͼΧʔεςΞʔζണୣࢦ਺ P.538〜 27
  24. Exposure and Covariate Assessment in Social Epidemiology • ॅΈ෼͚ͱ͸ࣾձతΞΠσϯςΟςΟʹؔ͢Δݸਓͷମܥతͳ෺ཧత഑ஔͷई౓ •

    ࠷΋ଟ͍ͷ͸ਓछຽ଒Ͱ͋Γɼ஍Ҭࣾձ·ͨ͸౎ࢢ΍܊ͳͲͷΑΓେ͖ͳۭؒ୯ҐͰ ߦΘΕΔ • ॅΈ෼͚͸ɼࣗൃతͳબ୒ͱॅ୐ࢢ৔ʹ͓͚Δࠩผ΍Ҡಈʹର͢ΔܦࡁతোนͳͲͷ ඇࣗൃతͳ੍໿ΛؚΉෳࡶͳཁҼͷ૊Έ߹Θ͔ͤΒੜ͡Δ • .BTTFZBOE%FOUPO  ͸ɼډॅ஍ͷਓछִ཭ʹؔ͢Δͷ౷ܭతࢦඪΛಛఆ͠ɼ ۉҰੑɼമ࿐ɼूதɼूதԽɼΫϥελʔԽͱ͍͏ͭͷҟͳΔ࣍ݩʹάϧʔϓԽͨ͠ Segregation(1) P.539〜 28
  25. Exposure and Covariate Assessment in Social Epidemiology മ࿐ • ଟ༷ͳࣾձूஂͷϝϯόʔؒͷજࡏతͳ઀৮·ͨ͸૬ޓ࡞༻ͷఔ౓ʹؔ܎͢Δִ཭Λ

    ද͢ .BTTFZ͓Αͼ%FOUPO  ʹΑͬͯಛఆ͞Εͨമ࿐ͷͭͷई౓͸ɼϥϯμϜʹબ ୒͞Εͨগ਺೿͕ɼۭؒ୯ҐΛଟ਺೿ʢ૬ޓ࡞༻ࢦ਺ʣ·ͨ͸ผͷগ਺೿ʢ෼཭ࢦ਺ʣ ͱڞ༗͢Δ֬཰Λද͢ • ͭͷάϧʔϓ͚ͩΛߟྀͨ͠৔߹ɼ͜ΕΒͭͷई౓͸ͭʹू໿͞ΕΔ Segregation(2) ۉҰੑ • গ਺೿άϧʔϓ͕ۭؒతʹҰ༷ʹ෼෍͢Δఔ౓ͰԼهͷࢦඪʹΑΓ౷ܭతʹධՁՄ ʢඇྨࣅੑࢦ਺ɼδχ܎਺ɼΞτΩϯιϯࢦ਺ɼςΠϧͷΤϯτϩϐʔʣ P.539〜 29
  26. Exposure and Covariate Assessment in Social Epidemiology ूத౓ • ࣾձूஂ͕઎ΊΔ෺ཧతۭؒͷ૬ରతͳྔΛද͢

    • .BTTFZͱ%FOUPOʹΑͬͯ֬ೝ͞Εͨͭͷूத౓ଌఆ๏  ͷதͰɼ࠷΋ݹ͍ͷ ͸)PPWFSͷʮσϧλʯɽۭؒ୯Ґʹ͓͚ΔϚΠϊϦςΟͷׂ߹ͰɼฏۉҎ্ͷϚΠϊ ϦςΟͷີ౓Λ͍࣋ͬͯΔ தԝूݖԽ • ର৅ͱͳΔΑΓ޿͍஍Ҭͷ஍ཧతத৺ʹର͢Δগ਺ຽ଒ͷҐஔΛࢦ͢ • தԝूݖԽͷ૬ରతई౓͸ɼଟ਺೿ूஂͷΑ͏ʹ෼෍͢ΔͨΊʹۭؒ୯ҐΛมߋ͠ͳ͚ Ε͹ͳΒͳ͍গ਺೿ूஂͷׂ߹Λද͢ • தԝूݖԽͷઈରతई౓͸ɼଟ਺೿ूஂͷ෼෍ʹؔ܎ͳ͘ɼগ਺೿ूஂͷۭؒ෼෍ͷΈ Λߟྀ͢Δ Segregation(3) P.539〜 30
  27. Exposure and Covariate Assessment in Social Epidemiology ΫϥελϦϯά • গ਺ऀ͕ྡ઀ۭͨؒ͠୯ҐͰੜ׆͍ͯ͠Δ͔Ͳ͏͔Λද͢෼཭ͷ࣍ݩ

    • ΫϥελʔԽͷઈରࢦඪ͸ɼྡ઀͢Δۭؒ୯Ґͷগ਺ຽ଒ͷฏۉ਺ΛɼͦΕΒͷ୯Ґͷ ෼฼ूஂશମʹର͢Δׂ߹ͱͯ͠ଌఆ͢Δ • ૬ରతΫϥελϦϯάई౓͸ɼϥϯμϜʹબ୒͞Εͨ೚ҙͷͭͷগ਺ऀؒͷ༧૝ڑ཭ ͱɼϥϯμϜʹબ୒͞Εͨ೚ҙͷͭͷଟ਺ऀؒͷ༧૝ڑ཭ͱΛൺֱ͢Δ • .BTTFZͱ%FOUPO͸ʮڑ཭ݮਰ૬ޓ࡞༻ʯͱʮڑ཭ݮਰ෼཭ʯͱ͍͏ई౓΋ఏҊͯ͠ ͍Δ͕ɼ͜Ε͸গ਺೿͕࣍ʹૺ۰͢Δਓ͕ͦΕͧΕଟ਺೿·ͨ͸গ਺೿άϧʔϓͷϝϯ όʔͰ͋Δ֬཰Λද͢ Segregation(4) P.539〜 31
  28. Exposure and Covariate Assessment in Social Epidemiology • ࠷େͷؔ৺͸ܦࡁతෆฏ౳ɼྫ͑͹ॴಘ΍෋ͷਓޱʹ͓͚Δෆฏ౳ͳ෼഑ʹूத͢Δ •

    աڈ೥ؒͷࣾձӸֶత׆ಈͷओཁͳয఺Ͱ͕͋ͬͨɼ͜Ε͸Ұ෦ʹ͸೥Ҏ߱ͷ ઌਐ޻ۀࣾձʹ͓͚Δॴಘ͓Αͼ෋ͷෆฏ౳ͷ૿Ճʹഥं͕͔͔ͬͨͨΊͰ͋Δ • ͜ͷજࡏతަབྷ͸ɼߏ੒Λॴಘෆฏ౳ͷจ຺ͷޮՌ͔Β੾Γ཭͢໰୊ͱͯ͠આ໌͞Εͯ ͓Γɼ͜ͷ໰୊ʹରॲ͢ΔͨΊʹաڈे೥ؒʹଟॏճؼϞσϧ͕޿͘࢖ΘΕΔΑ͏ʹ ͳͬͨ • ͦΕʹ΋͔͔ΘΒͣɼʢͨͱ͑͹ਅͷؔ܎͸ඇઢܗ͕ͩɼઢܗճؼΛ࢖༻͢ΔʣϞσϧ ͷ࢓༷ͷޡΓ͸ɼͨͱ͑ෆฏ౳ͷਅͷҼՌతޮՌ͕ͳͯ͘΋ɼෆฏ౳ͱ݈߁ͷ݁ՌΛ ؔ࿈ͤͨ͞··ʹ͢Δ Inequality(1) P.540〜 32
  29. Exposure and Covariate Assessment in Social Epidemiology • ϩʔϨϯπۂઢΛ࡞੒͢Δʹ͸ɼର৅ͱͳΔྔZ͢ͳΘͪॴಘʹԠͯ͡Z≤Z≤Z≤ ͱͳΔΑ͏ʹɼूஂதͷOݸͷݸମΛॱҐ෇͚͢Δ

    • ≤ZOͰ͋Γɼ࠷খͷॴಘ஋͔Β࠷େͷॴಘ஋·ͰਓޱΛ௨ա͢Δ • ϩʔϨϯπۂઢͷԣ࣠͸ɼ೚ҙͷ఺' Z Ͱ߹֨ͨ͠ݸମͷྦྷੵׂ߹Λࣔ͠ɼࠨͷ͔ Βӈͷ·Ͱͷ஋ΛͱΔ • ॱҐ͚ͮ͞Εͨݸମ͕઎ΊΔॴಘͷྦྷੵγΣΞЇ Z ͸ɼಉ༷ʹॎ࣠ʹه࿥͞Ε͍ͯΔɽ ͢ͳΘͪॴಘ஋ͷࠨ͔ΒӈʹҠಈ͠ͳ͕ΒॴಘZJʹ౸ୡ͢ΔͱɼͦͷZJͷࠨʹ૬౰͢Δ ݸମͷྦྷੵॴಘׂ߹Q͕ϓϩοτ͞ΕΔɽ' Z ରЇ Z ͷάϥϑ͸ϩʔϨϯπۂઢ ਤ  Ͱ͋Δɽݸମ͸ϥϯΫॱͰ͋ΔͷͰɼۂઢ͸ৗʹ›ͷର֯ઢʢ׬શฏ౳ͷ৔ ߹ʣʹԊͬͯଘࡏ͢Δ͔ɼର֯ઢͷԼͰݫີʹತͰͳ͚Ε͹ͳΒͳ͍ʢෆ౳͕ࣜ͋Δ৔ ߹ʣ Inequality(2) P.540〜 33
  30. Exposure and Covariate Assessment in Social Epidemiology • ݈߁ݚڀʹ͓͚Δࣾձࢿຊͷڞ௨తͳࢦඪ͸ɼ౤ථͳͲͷࢢຽࢀՃͷࢦඪ΍ɼ೚ҙஂମ ΁ͷՃೖ཰΍ใࠂ͞Εͨʮରਓ৴པײʯͷਫ४ʹؔ͢Δௐࠪͷճ౴Ͱ͋Δ

    • ࣾձࢿຊͷ֓೦ͱີ઀ʹؔ࿈͍ͯ͠Δͷ͸ɼࣾձֶͷதͰํ๏࿦Λཱ͍֬ͯ͠Δ͕ɼ ެऺӴੜͷݚڀͰ͸͋·ΓҰ؏ͯ͠ద༻͞Ε͍ͯͳ͍ࣾձωοτϫʔΫͷݚڀͰ͋Δ • ࣾձతωοτϫʔΫͷ෼ੳ͸ɼूஂ಺ͷݸਓؒͷͭͳ͕Γͷߏ଄ͱɼͦΕΒ͕ͲͷΑ͏ ʹ৘ใɼ෺࣭తࢧԉɼ͞Βʹ͸ײછੑҼࢠΛ఻ୡ͢ΔΑ͏ʹػೳ͍ͯ͠Δ͔Λߟྀͨ͠ ૯߹తͳϨϕϧʹ͋Δ Social Capital P.541〜 34
  31. Exposure and Covariate Assessment in Social Epidemiology LSTL͞Μ͔Βͷ͝঺հ͍͍ͨͩͨ࿦จͷ͓࿩ Rehkopf, D.

    H., Glymour, M. M., & Osypuk, T. L. (2016). The consistency assumption for causal inference in social epidemiology: when a rose is not a rose. Current epidemiology reports, 3(1), 63-71. ࿦จͷओͳ಺༰ • ࣾձӸֶݚڀʹ͓͚Δ$POTJTUFODZͷॏཁੑ • $POTJTUFODZͷԾఆ͕ͲͷΑ͏ʹҧ൓͞ΕΔͷ͔ྫΛ༻͍ͯࣔ͢ 35
  32. Exposure and Covariate Assessment in Social Epidemiology $POTJTUFODZͷԾఆΛຬͨ͢͜ͱͷॏཁੑ Ӹֶऀ͸ɼ؍ଌ͞Εͨσʔλʹର͠ɼҼՌਪ࿦ʢ൓ࣄ࣮త·ͨ͸જࡏతPVUDPNF΁ͷΞϓ ϩʔνʣΛߦ͏͜ͱʹΑΓհೖͷӨڹΛ༧ଌ͢ΔͨΊʹɼ࣍ͷͭͷԾఆΛ༻͍Δ

    • &YDIBOHFBCJMJUZʢQPUFOUJBMPVUDPNFͷਪఆ͕ՄೳͰ͋Δ͜ͱɿަབྷͷௐ੔ʣ • 1PTJUJWJUZʢൺֱՄೳͰ͋Δ͜ͱɿ֤૚಺ʹ࣏ྍ܈ͱඇ࣏ྍ܈͕ଘࡏ͢Δʣ • $POTJTUFODZʢമ࿐͕े෼ͳಛҟੑΛ͍࣋ͬͯΔ͜ͱʣ &YDIBOHFBCJMJUZͱ1PTJUJWJUZ͸͜Ε·Ͱ΋ॏཁࢹ͞Ε͖͕ͯͨɼ $POTJTUFODZ͸͋·Γॏཁࢹ͞Εͳ͔ͬͨɽ ͔͠͠ʜ • $POTJTUFODZͷԾఆΛແࢹ͢Δ͜ͱ͸ɼ0VUDPNFʹҟͳΔӨڹΛٴ΅͢ • $POTJTUFODZͷԾఆ͕ҧ൓͞Εͳ͍Α͏஫ҙ͢Δ͜ͱ͸ɼ ΑΓޮՌతͳհೖσβΠϯΛઃܭ͢ΔͨΊʹ༗༻Ͱ͋Δ ͜ͱ͕ઌߦݚڀͰࣔ͞Ε͍ͯΔ 36
  33. Exposure and Covariate Assessment in Social Epidemiology $POTJTUFODZͷԾఆͷҧ൓ྫ ޮՌम০ •

    ʮࡀҎ্ͷೖֶ WTࡀҎ্ͷೖֶʯPSʮࡀͰͷೖֶ WTࡀͰͷೖֶʯ • ৺࣬ױʹର͢ΔࣾձతࢧԉͷӨڹ͕உঁؒͰҟͳΔͷʹ૚ผ͍ͯ͠ͳ͍ ഔհܦ࿏ • ڭҭ͸ɼ஌ࣝͱೝ஌ೳྗͷ޲্ɼࢿ֨ͷऔಘɼ஍Ґͷ޲্ɼιʔγϟϧωοτϫʔΫͷ มԽΛ௨݈ͯ͡߁ʹӨڹΛ༩͍͑ͯΔ հೖͷఆٛʢൣғʣͷ͍͋·͍͞ • հೖ͸े෼ͳಛҟੑΛ࣋ͬͯఆٛ͞ΕΔඞཁ͕͋Δ͕ɼհೖͷઆ໌͕ෆඞཁʹ۩ମతͰ ͋Δͱকདྷͷ࠶ݱੑ͕๦͛ΒΕΔ ॴಘɿऩೖʹ͸͍ΖΜͳछྨ͕͋Δʢڅ༩ɼ੫ۚؐ෇ɼౌ͚ɼ૬ଓɼๅ͘͡ͷ৆ۚʣ ڭҭɿओʹमྃ೥ɼऔಘֶҐͰΧςΰϦʔ෼͚͞ΕΔ͕ɼࣝࣈ཰͸݈߁ʹӨڹΛٴ΅͢ ॏཁͳҼࢠͰ͋Δ ஍Ҭɿઃఆͨ͠հೖҎ֎ͷཁҼʢҠಈ੓ࡦɼ஍Ҭ׆ੑԽɼ஍ҬͷߴڃԽʣ͕݈߁ʹӨڹΛ ༩͑ΔՄೳੑ͕͋Δ 37
  34. Exposure and Covariate Assessment in Social Epidemiology $POTJTUFODZͷԾఆΛҧ൓͠ͳ͍ͨΊʹ ࣾձӸֶऀʹର͢Δͭͷקࠂ •

    മ࿐ͷԾఆΛ໌ࣔ͠ɼཧ࿦త͓Αͼ࣮ݧతূڌͷ྆ํʹج͍ͮͯજࡏతʹؔ࿈͢Δมಈ Λಛఆ͢Δ΂͖ • മ࿐ͷൣғ͕$POTJTUFODZͷԾఆʹҧ൓͠ͳ͍͜ͱΛࣔࠦ͢Δ݁Ռ͕ಘΒΕΔ·Ͱ͸ɼ മ࿐ͷมಈͷൣғΛॖখͯ͠ݕ౼͢ΔΑ͏౒ΊΔ΂͖ • ՄೳͳݶΓɼ̍ͭͷമ࿐ʹ͍ͭͯෳ਺ͷҟͳΔఆٛΛ໌ࣔతʹݕূ͢Δ΂͖ ࣾձӸֶݚڀͰ͸ɼ$POTJTUFODZͷԾఆΛຬͨͨ͢Ίʹଟ͘ͷ஫ҙ͕ඞཁͰ͋Δ $POTJTUFODZͷԾఆΛຬͨ͢͜ͱ͸ɼ؍࡯ݚڀͱݚڀ݁Ռʹجͮ͘ߦಈʹ͍ͭͯͷਪ࿦Λ ΑΓۙ͘͢Δ͜ͱΛՄೳʹ͢Δ 38
  35. Causation and Confounding in Social Epidemiology Exposure and Covariate Assessment

    in Social Epidemiology • Social Factors Defined and Measured at the Individual Level • Social Factors Defined and Measured at the Aggregate Level Analytic Approaches • Multilevel Modeling • Marginal Models • Effect Decomposition • Life-Course SES Concepts • Experiments and Quasi-Experiments • Narrative Historical Approach Chapter26 Social Epidemiology Jay S. Kaufman 39
  36. Analytic Approaches Multilevel Modeling P.542〜 • աڈ਺े೥ؒͷ౷ܭֶతֵ৽ͷதͰɼ.VMUJMFWFMNPEFM΄ͲࣾձӸֶݚڀʹີ઀ʹ ݁ͼ͍ͭͨ΋ͷ͸ͳ͍ • ͜ͷํ๏ͱԠ༻ͷ༥߹͸ɼཧ࿦ͱٕज़ͷֵ໋͕΄΅ಉ࣌ʹىͬͨ͜೥ॳ಄ʹى

    ͬͨ͜ ཧ࿦తʹ໌Β͔ʹͳͬͨ͜ͱ • ࣾձӸֶݚڀ͸ɼ֊૚ߏ଄Λ໌֬ʹઆ໌͠ͳ͚Ε͹લਐͰ͖ͳ͍ • ͦͷඞཁੑ͸$IJOFTFCPYFTͱ͍͏ααʔͷൺᄻʹΑͬͯڧ͘໌֬ʹࣔ͞Εͨ • $IJOFTFCPYFTύϥμΠϜ͸ɼ఻౷తͳӸֶతϒϥοΫϘοΫεΛ෼ࢠϨϕϧ͔Β ݸਓϨϕϧɾࣾձϨϕϧ·Ͱɼ૊৫ͷෳ਺ͷೖΕࢠঢ়ͷϨϕϧΛแؚ͢ΔΑ͏ʹ ֦ு͢Δ͜ͱΛҙਤͨ͠ 40
  37. Analytic Approaches • ΫϥελʔԽ͞ΕͨσʔλΛҰൠతͳ౷ܭιϑτ΢ΣΞͰճؼ෼ੳ͢Δख๏͕ొ৔͠ɼ ೥୅ʹ͸ϥϯμϜ܎਺ϞσϧͱਓޱฏۉϞσϧͷ։ൃͱಋೖ͕ٸ଎ʹਐΜͩ • .VMUJMFWFMNPEFMͱ͍͏༻ޠ͸ɼݱࡏͰ͸ΫϥελʔԽ͞ΕͨσʔλʹରԠ͢Δ ͋ΒΏΔ౷ܭతख๏ΛؚΉ΄Ͳ޿͘࢖༻͞Ε͍ͯΔ • ϥϯμϜ܎਺Ϟσϧ͸ࣾձӸֶతͳద༻ʹ͓͍ͯҰൠతͳܗࣜͱͳ͍ͬͯΔ

    ٕज़తʹ໌Β͔ʹͳͬͨ͜ͱ • Ӹֶऀ͕ૄͳηϧΛ࡞੒ͤͣʹෳ਺ͷڞมྔΛ৚݅ͱ͢ΔͨΊʹճؼ๏ʹେ͖͘ґଘ ͢ΔΑ͏ʹͳͬͨ • ඪ४తͳϞσϧϑΟοςΟϯά๏Ͱ͸ɼಠཱͨ͠؍࡯ɼ͢ͳΘͪɼΫϥελʔແ࡞ҝԽ ࢼݧ΍൓෮ଌఆΛ൐͏ίϗʔτݚڀͷΑ͏ͳݚڀσβΠϯͷԼͰɼ͋Δ͍͸σʔλ͕஍ Ҭ಺ͷݸਓͷΑ͏ͳࣗવͳ֊૚ͷ͍͔ͭ͘ͷϨϕϧͰऩू͞ΕΔ৔߹ʹ͸ޡ͍ͬͯΔͱ Ծఆ͍ͯ͠Δ • ڞมྔΛίϯτϩʔϧͨ͠ޙ΋ɼΫϥελʔม਺ʢ஍ҬͳͲʣ͕ґવͱͯ͠PVUDPNF Λ༧ଌ͢Δ৔߹ɼ͜ͷม਺Λແࢹ͢Δ෼ੳ͸ɼ஍ҬϨϕϧͷ༧ଌҼࢠͷਪఆ܎਺ʹ͍ͭ ͯόΠΞεͷ͔͔ͬͨ෼ࢄਪఆ஋Λੜ੒͠ɼͦͷͨΊແޮͳݕఆ͓Αͼ۠ؒΛ΋ͨΒ͢ ౷ܭతδϨϯϚ P.542〜 41
  38. Analytic Approaches ஍ҬɿϨϕϧ .VMUJMFWFMNPEFMͷ֓೦ͷઆ໌ ݸਓɿϨϕϧ ʹॅΜͰ͍Δ ਓͷ࿈ଓతͳPVUDPNF Λߟ͑Δ ஍ҬN ஍Ҭ

    ݸਓ ਓ ஍Ҭ ɾɾɾ ɾɾɾ 尾崎幸謙,川端⼀光,⼭⽥剛史.[編著]『 Rで学ぶマルチレベルモデル[⼊⾨編]―基本モデルの考え⽅と分析―』 朝倉書店, P3.を参考にして作成 ݸਓ ਓ ݸਓ ਓ ͸஍Ҭ͝ͱʹฏۉ ͓Αͼ෼ࢄ ͷਖ਼ن෼෍ʹै͏ P.542〜 42
  39. Analytic Approaches • ੾ยʹద༻͞ΕΔϥϯμϜ܎਺ͷ֓೦͸ɼ஍Ҭ͝ͱͷฏۉ ΋ط஌ͷܗͷϥϯμϜ ͳ෼෍ʹΑͬͯهड़Ͱ͖ΔͱԾఆ͍ͯ͠Δ • ஍Ҭ͝ͱͷฏۉ ΋ɼฏۉ ͱ෼ࢄ

    Ͱਖ਼ن෼෍͢ΔͱԾఆ͢Δͱɼ ࣍ͷͭͷ֊૚ͷϞσϧ͕ੜ͡Δ ʢϨϕϧʣ ʢϨϕϧʣ P.542〜 ݻఆޮՌ ʢूஂʹΑͬͯมಈ͠ͳ͍ύϥϝʔλʣ ஍Ҭͷ۠ผʹΑΒͳ͍໨తม਺ͷظ଴஋ ϥϯμϜޮՌ ʢूஂʹΑͬͯมಈ͢Δύϥϝʔλʣ Λத৺ʹ֬཰తʹมಈ͢Δ஍Ҭ KͷޮՌ ϥϯμϜ੾ย ஍Ҭ Kͷ฼ฏۉ ޡ߲ࠩ ݸਓ J ͷ஍Ҭ Kͷ฼ฏۉͱͷဃ཭ 43
  40. Analytic Approaches ͜͜Ͱ ɼ ɼ Ͱ͋Γɼ Ϩϕϧͷ ΛϨϕϧͷ੒෼ʹஔ͖׵͑ͨ߹੒Ϟσϧ͸ҎԼͷͱ͓Γ P.542〜 ͜ͷϞσϧ͸ɼݸਓʹΑΔߏ੒ཁૉͱ஍ҬʹΑΔߏ੒ཁૉʹՄมੑΛ෼ׂ͢Δ͜ͱ͔Βɼ

    Ұํ޲ϥϯμϜޮՌ෼ࢄͱͯ͠΋஌ΒΕ͍ͯΔ ૯ฏۉ ஍Ҭ͝ͱͷ ภࠩ ݸʑͷภࠩ ڃ಺૬ؔ܎਺ʢ*$$ɿJOUSBDMBTT PSJOUSBDMVTUFS DPSSFMBUJPODPFGGJDJFOUʣ • શ෼ࢄʹର͢Δ෼ࢄ੒෼ͷ૬ରతد༩͸ɼڃ಺૬ؔ܎਺ʹΑͬͯද͢͜ͱ͕Ͱ͖Δ • ڃ಺૬ؔ܎਺ͱ͸ɼ஍Ҭ಺ͷݸਓؒͰ͸ͳ͘஍ҬؒͰى͜Δ:ͷมಈͷׂ߹Ͱ͋Δ 44
  41. Analytic Approaches P.542〜 ަޓ࡞༻߲ ͜ͷϞσϧʹ͸ɼڞมྔ9ͱ;ͷؒͷΫϩεϨϕϧʢ૬ޓ࡞༻ʣ߲ɼ͓Αͼ9ͱϥϯμϜ ޮՌ ͷؒͷੵؚ͕·ΕΔ ϨϕϧϞσϧͷ܎਺ΛϨϕϧϞσϧͷํఔࣜʹஔ͖׵͑ͯɼ୯Ұͷ݁߹ํఔࣜΛ࡞੒ ͢Δ͜ͱͰ֬ೝՄೳ ʢϨϕϧʣ

    and ݸਓ ूஂ ͜ͷϞσϧʹΑΕ͹ɼ஍Ҭ Kʹ͓͚Δ݁Ռ:ʹର͢Δ9ͷޮՌ͸ɼͦͷ஍Ҭʹ͓͚Δ;ͷ Ϩϕϧ͓ΑͼϥϯμϜޮՌʢϨϕϧͷޡ߲ࠩʣ ʹґଘ͢Δ ;ͷϢχοτͰ͸ɼ͜ͷϥϯμϜޮՌ ͸ɼ஍Ҭ Kʹ͓͚Δ9ޮՌͷ͢΂ͯͷ஍Ҭʹ ͓͚Δฏۉ9ޮՌ ͔ΒͷภࠩͰ͋Δ 47
  42. Analytic Approaches • Ϋϥελؒͷ:ͷฏۉ஋ͷมԽΛهड़͢Δ • ϥϯμϜ߲ͱͯ͠ΫϥελޮՌΛೖྗ͢Δ୅ΘΓʹΫϥελ಺૬ؔͷύϥϝʔλΛಋೖ ͠ɼ͜ΕΒͷ૬ؔΛՄೳʹ͢ΔϑΟοςΟϯά๏ʢ(&&ɿHFOFSBMJ[FEFTUJNBUJOH FRVBUJPOTʣΛ࢖༻͢Δ͜ͱʹΑͬͯΫϥελޮՌΛߟྀ͢Δ • ෳ਺ϨϕϧͱΈͳ͢͜ͱ͕Ͱ͖Δ͕ΫϥελޮՌͷ෼෍Λ௚઀ϞσϧԽ͢Δ͜ͱ͸Ͱ͖

    ͳ͍ • Ϟσϧ಺ͷଞͷڞมྔΛ৚݅ͱͯ͠ɼશूஂʹ͓͚Δ9ͷมԽʢ͢ͳΘͪɼ͢΂ͯͷΫ ϥελʹΘͨΔ9ͷ୯ҐมԽͷ:ͷฏۉʹର͢ΔޮՌʣ͕:ʹٴ΅͢ӨڹΛਪఆ͢Δͷ ʹద͍ͯ͠Δ • .BSHJOBMNPEFM͸(-.ͷ֦ுʹ͗͢ͳ͍ .BSHJOBMNPEFMͷಛ௃ P.544〜 49
  43. Analytic Approaches .VMUJMFWFMNPEFMʢ.JYFEʣ .VMUJMFWFMNPEFMͱͷϞσϧͷҧ͍ .BSHJOBMNPEFMʢ(&&ʣ 03 03 03 03 ڵຯͷ͋ΔڞมྔҎ֎ͷڞมྔͱΫϥελʔΛ

    ৚͚݅ͮΔ͜ͱʹΑΓΫϥελʔߏ଄Λߟྀ Ϋϥελ಺૬ؔΛϞσϧʹ૊ΈࠐΉ͜ͱʹΑΓ Ϋϥελʔߏ଄Ͱ͋Δ͜ͱΛߟྀ ʢަ׵Մೳͳ૬ؔɼࣗݾ૬ؔɼແߏ଄ɼಠཱʣ มྔޮՌ ڞมྔϕΫτϧ ճؼ܎਺ ڞมྔϕΫτϧ Ϋϥελ಺૬ؔΛ ߟྀͨ͠ύϥϝʔλ P.544〜 Hosmer Jr, D. W., Lemeshow, S., & Sturdivant, R. X. (2013). Applied logistic regression (Vol. 398). John Wiley & Sons. 50
  44. Analytic Approaches .VMUJMFWFMNPEFMͱͷղऍͷҧ͍ Hosmer Jr, D. W., Lemeshow, S., &

    Sturdivant, R. X. (2013). Applied logistic regression (Vol. 398). John Wiley & Sons. P.544〜 ڵຯͷ͋Δม਺ • ϲ݄લʹ֏෩अʹ͔͔͔ͬͨ ʢ೥ؒຖ݄ଌఆʣ • ਓछʢനਓɼനਓҎ֎ʣ 0VUDPNF ᄶଉൃ࡞ ྫʣ $2ɿෳ਺͋Δม਺ͷ͏ͪɼͲͷม਺͕ࢠͲ΋ͷᄶଉͷൃੜʹӨڹΛ༩͑Δ͔ 51
  45. Analytic Approaches .VMUJMFWFMNPEFMʢ.JYFEʣ .VMUJMFWFMNPEFMͱͷղऍͷҧ͍ .BSHJOBMNPEFMʢ(&&ʣ 03  03  03

     03  ࢠͲ΋ ֏෩अ લNͷࢠͲ΋͕࣍ͷ݄ʹᄶଉΛى͜͢ Φοζ͕ഒ ݸਓʹରͯ͠ݴٴ લNʹ֏෩अʹ͔͔ͬͨࢠͲ΋ͷᄶଉൃ࡞ͷ Φοζ͸֏෩अʹ͔͔Βͳ͔ͬͨࢠͲ΋ͷഒ ूஂʹରͯ͠ݴٴ ਓछ ಉ͡มྔޮՌΛ࣋ͭനਓҎ֎ͷࢠͲ΋͕ നਓͷࢠͲ΋ΑΓᄶଉΛى͜͢Φοζ͕ഒ ಉ͡ࢠͲ΋಺ͰมྔޮՌ΍ਓछ͕มΘΒͳ ͍ͷͰҙຯ͕ͳ͍ നਓҎ֎ͷूஂ͸നਓͷूஂͷᄶଉൃ࡞ͷ Φοζ͕ഒ ࢠͲ΋ ࢠͲ΋ ࢠͲ΋ N N N N N N N N N N N N P.544〜 Hosmer Jr, D. W., Lemeshow, S., & Sturdivant, R. X. (2013). Applied logistic regression (Vol. 398). John Wiley & Sons. 52
  46. Analytic Approaches Effect Decomposition P.545〜 • ࣾձӸֶʹ͓͚Δ෼ੳํ๏ͷ̍ͭ • ؔ৺ͷ͋Δࣾձతമ࿐ʹର͢Δͭͷௐ੔͞Εͨਪఆ஋Λରൺ͢Δ͜ͱʹΑΔޮՌͷ ෼ղͰ͋Δ

    • മ࿐͕݁ՌʹӨڹΛٴ΅͢ܦ࿏্ʹม਺ʢதؒม਺ɿ;ʣ͕ଘࡏ͢Δ͜ͱΛԾఆ͢Δ • தؒม਺;Λհͨ͠മ࿐ͷؒ઀ޮՌͱதؒม਺;Λհ͞ͳ͍௚઀ޮՌͱΛ۠ผ͢Δ • தؒม਺;͕മ࿐ͷӨڹΛݮগͤ͞Δ৔߹ɼമ࿐ͷӨڹ͸ഔհ͍ͯ͠Δͱਪఆ͞ΕΔ X Y Z %*3&$5 */%*3&$5 தؒม਺ മ࿐ ݁Ռ 54
  47. Analytic Approaches P.545〜 • தؒม਺Λௐ੔͢Δͱ͜Ε·Ͱଘࡏ͠ͳ͔ͬͨަབྷ͕ੜ͡Δ • ௚઀ޮՌͷେ͖͕͞૯߹ޮՌʢ5PUBMFGGFDUʣΑΓେ͖͘ͳΔ͜ͱ͕͋Δ ߴߍதୀ ௚઀ޮՌ ؒ઀ޮՌ

    ໰୊఺ ྫʣ૯߹ޮՌɿߴߍதୀ͕ϗʔϜϨεʹ༩͑ΔӨڹ தؒม਺ɿࣦۀ ϗʔϜϨε ࣦۀ ߴߍதୀ ϗʔϜϨε ૯߹ޮՌ ޮՌͷ෼ղ 55
  48. Analytic Approaches P.545〜 X Z Y ߴߍଔۀΛଅਐ͞Ε͔ͨͲ͏͔ʹ͔͔ΘΒͣɼ ޏ༻ଅਐ͕ͳ͚Ε͹൴Β͸ࣦۀ͢Δ 0 →

    1 1 → 1 ߴߍଔۀΛଅਐ͞Ε͔ͨͲ͏͔ʹ͔͔ΘΒͣɼ ޏ༻Λڋ൱͞ΕͨΒ൴Β͸ϗʔϜϨεʹͳΔ 0 → 1 → 1 1 → 1 → 1 ޏ༻ଅਐΛߦͬͨ৔߹ɼߴߍଔۀ͢Ε͹ϗʔϜϨεʹ ͸ͳΒͳ͍͕ɼߴߍதୀͱͳΕ͹ϗʔϜϨεʹͳΔ 0 → 0 → 0 1 → 0 → 1 ࣍ͷͭͷհೖʹ͍ͭͯएऀ͕ಉ͡൓ԠΛࣔ͢ͱԾఆ • ߴߍڭҭͷऴྃΛ঑ྭ • ޏ༻ଅਐʢ܇࿅΍৬ۀ঺հʣ 9ɿڭҭ ;ɿޏ༻ :ɿϗʔϜϨε ̌ ߴߍଔۀ ब৬ Ͱͳ͍ ̍ ߴߍதୀ ແ৬ Ͱ͋Δ 56
  49. Analytic Approaches 9ͷ૯߹ޮՌ  ʔ    ޏ༻͋Γʢ ;ʣʹݻఆͨ࣌͠ͷ௚઀ޮՌ

     ʔ    9ͷશޮՌʢʣʹޮՌΛ෼ղͨ͠ޙͷ௚઀ޮՌʢʣؚ͕·Εͳ͍ͨΊɼ શޮՌΛ௚઀ޮՌͱؒ઀ޮՌʹ෼ׂ͢Δͱ͍͏֓೦͸ෆे෼ 9ͷ૯߹ޮՌ ௚઀ޮՌ ؒ઀ޮՌ P.545〜 57
  50. Analytic Approaches Life-Course SES Concepts • աڈ೥ؒͰٸ଎ʹൃలͨࣾ͠ձӸֶత֓೦ͷ̍ͭ • ੒ਓͷࣾձత஍Ґͱ݈߁ͱͷ୯७ͳԣஅతؔ࿈Ͱ͸ͳ͘ɼݸਓͷੜ֔ʹΘͨΔࣾձతമ ࿐ͷಈతͳي੻Λઆ໌͠Α͏ͱ͢Δ΋ͷ

    • ए೥ظͷࣾձతঢ়گ͕ຫੑ࣬ױͷ੒ਓϦεΫʹӨڹΛٴ΅͢ͱ͍͏ΤϏσϯεΛ஝ੵ͢ Δ͜ͱʹΑΓՃ଎͞Εͨ • ͜ͷੜ֔Ϟσϧ͸͙͢ʹ֦ு͞Εɼप࢈ظͱ੒ਓظͷ৚͚݅ͩͰͳ͘ɼੜ׆ͷશஈ֊Λ ௨ͯ͡ҟͳΔ৚݅ͱܦݧͷ૊Έ߹Θͤɼ஝ੵɼ૬ޓ࡞༻΋ߟྀ͞ΕΔΑ͏ʹͳͬͨ P.546〜 59
  51. Analytic Approaches Life-Course SES Concepts 4PDJBMNPCJMJUZNPEFM ਓੜͷ֤ଌఆ࣌఺Ͱࣾձత஍ҐͷԼҐͷΧςΰϦʔʹ͍ΔਓʑͱɼԼҐͷΧςΰϦʔ͔Β ্ҐͷΧςΰϦʔʹɼ͋Δ͍͸্ҐͷΧςΰϦʔ͔ΒԼҐͷΧςΰϦʔʹҠಈͨ͠ਓʑͷ ্޲͖·ͨ͸Լ޲͖ͷࣾձӡಈͷରরతͳύλʔϯ͕෼ੳͷର৅ͱͳΔ ͜ͷղੳతσβΠϯʹΑΓɼ݈߁ͷબ୒ʢ͢ͳΘͪපؾͷਓ͕පؾͷ݁Ռͱͯࣾ͠ձత஍

    ҐΛ௿Լͤ͞Δ͜ͱʣ΍ɼए೥ظͷണୣͱ੒ਓͷա৒ӫཆ΁ͷಉ࣌മ࿐͕৺݂؅࣬ױͷಛ ʹڧྗͳܾఆҼࢠͰ͋Δͱ͍͏࣌఺ؒͷ૬ޓ࡞༻Λߟྀ͢Δ͜ͱ͕Մೳ $VNVMBUJWFNPEFM ॏཁͳ࣌ظ΍ಛఆͷҠಈύλʔϯΛߟྀͤͣʹɼੜ֔Λ௨ͯ͡ͷ૕ࣦͷྦྷੵతͳ૯ޮՌΛ ߟྀ͢Δ P.546〜 61
  52. Analytic Approaches Experiments and Quasi-Experiments • ؍࡯తࣾձӸֶʹ͓͚Δڧ͍ަབྷͷՄೳੑΛߟ͑Δͱ3$5Λݕ౼͢Δͷ͸ࣗવͰ͋Δ • ैདྷͷରর࣮ݧͱ͸ҟͳΔσβΠϯʹΑͬͯϥϯμϜԽͷར఺ΛಘΔ͜ͱ͕Մೳ •

    മ࿐ׂ͕Γ෇͚ΒΕ͍ͯͳͯ͘΋മ࿐Λ༧ଌ͢ΔϥϯμϜׂ෇Λར༻͢Δ͜ͱ͕Մೳ ྫʣϕτφϜઓ૪࣌୅ͷฌ໾͕ઓޙͷୀ໾܉ਓͷࢮ๢཰ʹٴ΅͢Өڹʹ͍ͭͯɼ ग़ੜ೔Ͱແ࡞ҝநग़Λ͓͜ͳͬͨ ˠ બ୒όΠΞεΛճආ ϥϯμϜԽࢼݧͷऑ఺ɿҰൠԽՄೳੑ ɾࢀՃऀ͸ඇࢀՃऀͱҟͳΔ ɾࢀՃऀͷෆ९क ɾϓϥηϘ܈ɼରর܈ͷࢀՃऀͷߦಈม༰ ϥϯμϜԽࢼݧͷ࣮ࢪ͓Αͼղऍʹ͸ɼಛʹࣾձӸֶݚڀ͕ؔ৺ͷ͋Δෳࡶͳհೖʹؔ͠ ͯɼଞʹ΋ଟ͘ͷ੍ݶ͕͋Δ ͦͷͨΊ؍࡯ݚڀ͸͍ٙͳࣾ͘ձӸֶͷத৺Ͱ͋Γଓ͚ΔͰ͋Ζ͏ P.547〜 62
  53. Analytic Approaches Narrative Historical Approach • ࠷΋ݹ͘ɼ࠷΋޿͘༻͍ΒΕ͍ͯΔΞϓϩʔν͸ɼӸֶऀʹΑͬͯ࠷΋࢖༻͞Ε͍ͯͳ ͍ • മ࿐ͱͦͷ݁Ռʹ͍ͭͯɼ౷ܭϞσϧʹΑͬͯఆٛ͞Εͨந৅తͰཧ૝Խ͞Εͨจ຺Ͱ

    ͸ͳ͘ɼ࣮ࡍʹىͬͨ͜ಛఆͷࣾձ࢙తจ຺ͰޠΒΕΔ • ٞ࿦͸ఆྔతͰ͋Δ͕ɼճؼϞσϧ͸༻͍ΒΕͣɼ౷ܭతݕఆ΋࣮ࢪ͞Εͳ͍ • ҼՌؔ܎͕ओு͞ΕΔൣғͰɼ౷ܭతͱ͍͏ΑΓ΋࣮࣭తʹٞ࿦͞ΕΔ • ࣾձӸֶ͕ੈلʹൟӫ͢ΔͨΊʹ͸ɼ؍࡯σʔλΛ͔͋ͨ΋࣮ݧతͳࢼݧ͔Βੜ͡ ͔ͨͷΑ͏ʹѻ͏͚ͩͰ͸ɼ࠷ྑͷ౴͕͑ಘΒΕͳ͍͜ͱ΋ड͚ೖΕͳ͚Ε͹ͳΒͳ͍ • ঀड़తͳํ๏͸ཧ࿦ͷݯઘͰ͋Γɼͦͷ๛෋͞͸ɼ౷ܭֶͷ௒અ໿ओٛϞσϧΛ୅ද͢ Δεύϧλࣜͷ୯७Խ͞Ε͗͢ʹର͢Δوॏͳର߅఺ͱͳΔ P.548〜 63