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A journey in ‘omics research from the bottom of the ocean to the top of a mountain

A journey in ‘omics research from the bottom of the ocean to the top of a mountain

This slide deck gives an overview of my career trajectory (from bachelor's degree to post-doctoral research) and describes a current research project. This deck was prepared for a research seminar series (NSM90) at Sacramento State.

Rayna M Harris

April 09, 2020
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  1. A journey in ‘omics research from the bottom of the

    ocean to the top of a mountain April 9, 2020 Sacramento State University (NMS90) Dr. Rayna M. Harris Postdoc, UC Davis raynamharris 1
  2. Part 1: My career path Ph.D. student Unpaid intern Lab

    tech and manager Postdoctoral researcher By Caitlin Friesen By Rayna Harris By Rayna Harris Etsy Teaching assistant Needpix.com 5
  3. B.S. Biochemistry, University of Texas at Austin 2006 Why? It

    fulfilled all the pre-med requirements. But I soon realized I didn’t want to be that kind of doctor. 7
  4. Some molecular biology and data science keywords DNA RNA Protein

    genomics, genetics transcriptomics proteomics Molecular Biology Data Science/ Bioinformatics transcription (aka gene expression) translation 12
  5. Volunteer Instructor, The Carpentries 2015-2020 14 Translating lessons into Spanish

    Teaching Git in Argentina Instructor training in Latin America https://carpentries.org/
  6. Postdoc: Studying parental care while making science more inclusive to

    working mothers, 2019-current Image of parenting pigeons by Victoria Farrar Calisi & a Working Group of Mothers in Science 2018 PNAS 15 Calisi 2018 Science
  7. As a data scientist, I can work in the tropics,

    in the city or in the mountains 16 Home office Truckee, CA Coffee shop Austin, TX Community center Old San Juan, PR
  8. “Transcriptional symphony”: the orchestrated expression of genes that regulate a

    biological process 19 DNA RNA Protein genomics, genetics transcriptomics proteomics Molecular Biology Data Science/ Bioinformatics transcription (aka gene expression) translation Biological process of interest
  9. Parental care: behavior that promotes offspring survival 21 Image from

    Google. Quote from https://global.oup.com/academic/product/the-evolution-of-parental-care-9780199692583?cc=ca&lang=en&
  10. The Rock Dove Transcriptomics Team Dr. Rayna Harris Dr. Suzanne

    Austin Dr. Andrew Lang Dr. Matthew MacManes Dr. Rebecca Calisi Rechelle Viernes Dr. Jesse Krause April Booth Victoria Farrar University of California, Davis University of New Hampshire Funded by the National Science Foundation 23
  11. Research question: What genes in the reproductive axis (hypothalamus, pituitary,

    and gonads) promote parental care behavior in females and males? 25
  12. Which groups are most different? 27 1. A and B

    2. A and C 3. A and D 4. B and C 5. B and D 6. C and D
  13. Prolactin (PRL) gene expression is the highest at and around

    the hatch time point https://raynamharris.shinyapps.io/musicalgenes/ 28
  14. Genes that are co-expressed with PRL are known to influence

    development and cancer 29 https://github.com/macmanes-lab/DoveParentsRNAseq
  15. Musical genes: An app I made to visualize and sonify

    gene expression during parental care https://raynamharris.shinyapps.io/musicalgenes/ 30
  16. Breakout groups 31 Visit https://raynamharris.shinyapps.io/musicalgenes/. Pick a gene, tissue, and

    sex. Sonify and visualize its expression. Repeat and compare. Share your favorite.
  17. Many thanks to colleagues in the... 33 College of Natural

    Science, UT Austin Instituto Nacional de Biodiversidad, Costa Rica Neural Systems & Behavior Course, MBL The Carpentries Data-Intensive Biology Lab, UC Davis Birds, Brains & Behavior Lab, UC Davis Science & Technology Studies, UC Davis
  18. What questions do you have? Thank you for listening. Dr.

    Rayna M. Harris Postdoc, UC Davis raynamharris March 19, 2020 Sacramento State University (NMS90) 34