it. Tap into it. Clinical Decision Support Private and Public Insurers Public Health Medical Devices Employers Transac=on Services Hospitals & Physicians Pharmacies Government Medical Research Centers Pa=ent Educa=on Health Clubs Pharmaceu=cals Retail Clinics Pa=ents / Consumers Healthcare is now about ecosystems
it. Tap into it. Patients and Drs are organising themselves ..yet in a 2013 study of the Pharma industry, 86% of respondents indicated that Digital represented less than 20% of their overall marke=ng budgets Opportuni=es to engage with pa=ents and prescribers are growing, with a prolifera=on of websites and forums for online discussion & advice…
it. Tap into it. New complexity needs new tools: Cognitive computing Adapts & learns Understands natural language Generates & evaluates hypotheses Watson
it. Tap into it. Baylor College of Medicine mines science papers to make new discoveries Business Need • While well-studied, p53 is implicated in many cancers, and there is still a need to uncover new relationships between p53 gene, protein, chemicals, and bio-mechanisms • Needed a solution to build, extract, and understand key entities from the literature, such as chemicals, genes, proteins, profiles, relationships, ontologies, networks Watson Benefits • Mined the literature and retrieve specific gene interactions, and display them for study • Mapped and discovered relationships between p53 and relevant genes and networks • Validated current p53 knowledge and, at a rate much faster than current methods, revealed new unknown interactions for further analysis
it. Tap into it. 9 9 Client interested in repurposing drugs for other conditions, including the treatment of malaria Business Need • It took 10 of their scientists 14 months of research to identify 12 potential candidates for the treatment of malaria • The process of discovery needed to be accelerated Watson Benefits • In just a few weeks, Watson uncovered evidence of 11 candidates that could effect the pathway involved in malaria • Of the 11 candidates found, 6 matched those the company identified • The 5 additional candidates were some that the company had never considered, and are currently under investigation
it. Tap into it. 10 10 Client interested in extracting key information in toxicology reports to help inform new candidate safety assessment Business Need • Valuable information in toxicology reports is locked in long sections of text • Hundreds of these reports exist but there is no easy way to extract the knowledge they contain to provide insight into the safety of a new drug candidate Watson Benefits • Watson successfully extracted the information associated with compound safety and toxicity • Watson demonstrated it can unlock critical safety information from a large volume of toxicology reports and their associated notes
it. Tap into it. 11 11 Janssen sought to quickly perform a robust comparison of treatments Business Need • Across 3,000 studies, Janssen wanted to improve the sophistication and speed of the comparison of multiple treatments against each other • Assembling the correct data from 1,000s of clinical trials to effectively compare efficacy and safety of multiple potential treatments for a disease or condition • Current process is manual, slow, expensive and prone to error Watson Benefits • Watson accelerated the gathering of data from 1,000s of trials to minutes instead of months • Watson will enable researchers to analyze the effectiveness and safety of various treatments for different populations of patients
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