Everyone starts with a simple one-machine setup, running PHP(or whatever else you fancy), MySQL/PostgreSql and Apache/Nginx. Sooner or later that will not be enough, you will have more operations to do than can be done in a single request, or you will have some operations that need to be done in parallel, and you will be faced with some important architecture decisions.
This talk will show you how a distributed system built with Gearman looks like, and more importantly the strange and wonderful things you will encounter in production and how to prepare for them.