How to read DNA?

Transcript

1. H O W T O R E A D D

   N A ?

2. H E L A C E L L S (

   W H Y H E L A ? )

3. H E L A C E L L S It

   is the oldest and most commonly used human cell line. It was derived from cervical cancer cells taken on February 8, 1951, from Henrietta Lacks, a patient who eventually died of her cancer on October 4, 1951.

4. Let us assume you managed to extract the DNA from

   HELA cells D N A

5. D N A S

6. D N A I S V E RY L O

   N G

7. D N A S O U P

8. T H E N E W S PA P E

   R P R O B L E M

9. T H E N E W S PA P E

   R P R O B L E M

10. B A C K T O B I O L

    O G Y ? Bioinformatics Bioinformatics Biology Biology Biology

11. O V E R L A P P I N

    G I S E A S Y (if the sequence is known)

12. O V E R L A P P I N

    G I S H A R D (if the sequence is unknown) Find a path in the de Bruijn graph that visits every edge exactly once - Eulerian path

13. W H AT I S T H E FA S

    T E S T M A M M A L ?

14. S O , W H AT D I D J

    U N E 2 7 , 2 0 0 0 N Y T I M E S S AY ?

15. S O , W H AT D I D J

    U N E 2 7 , 2 0 0 0 N Y T I M E S S AY ?

16. T H A N K Y O U ! Presentation

    is based on materials from https://www.coursera.org/course/bioinformatics