This talk was presented to the Center for Population Biology group at UC Davis on October 6, 2015. I highlight previous work on speciation involving the sister mosquito species A. gambiae and A. coluzzii, most of which was done by the Vector Genetics Lab (led by Greg Lanzaro) and Drosophila folks from Davis. I also share some more preliminary work on complex insecticide resistance that appears to be increasing rapidly in these mosquitoes.