Gamma-Frailty, exp(β2) = 0.61, exp(β1) = 0.74 λ10(t) = const1, λ20(t) = const2 0.0 0.5 1.0 1.5 2.0 2.0 2.5 3.0 a Marginaler Hazard Control (x=0) Treatment (x=1) 0.0 0.5 1.0 1.5 2.0 a 0.74 0.76 0.78 0.80 time Marginal Hazard Ratio Marginal Hazard Marginal Hazard λ1(t|x) = λ10(t) exp(β1x) E(Z|x, D > t) decreasing in t Marginal Hazard Ratio λ1(t|x = 1) λ1(t|x = 0) = exp(β1) E(Z|x = 1, D > t) E(Z|x = 0, D > t) 6