Annotates adapter locations and insert DNA regions in the raw read. Used to break a read into subreads during secondary analysis mapping and Circular Consensus. Productivity Assignment = Assigns a productivity score of 0, 1 or 2 to each sequencing ZMW. High Quality Region Screening = Annotates the high quality sequencing regions of a read to be used during Raw Read Trimming. Read Quality Assignment = A trained prediction of a read’s mapped accuracy based on its pulse and base file characteristics (peak signal-to- noise ratio, average base QV, interpulse duration, and so on). Used during secondary analysis filtering.