Upgrade to Pro
— share decks privately, control downloads, hide ads and more …
Speaker Deck
Features
Speaker Deck
PRO
Sign in
Sign up for free
Search
Search
living in the year 2020
Search
andreas manz
June 25, 2001
Research
2
82
living in the year 2020
... short talk given in Berlin. Hotel Adlon, June 25-26, 2001.
andreas manz
June 25, 2001
Tweet
Share
More Decks by andreas manz
See All by andreas manz
biomimetics
amzamz
0
29
Human Document Project
amzamz
0
230
microfluidics vs. self-assembly
amzamz
0
260
Human Document Project - introduction, goals & a small project
amzamz
0
360
microfluidics & miniaturization for clinical diagnostics
amzamz
0
310
Human Document Project - introduction, goals & myself
amzamz
0
140
chip-based microfluidic methods for analytical chemistry
amzamz
0
120
on nanofluidics and why it is so great
amzamz
0
90
chip technology, nanoliters and picoliters - miniaturization of (bio)analytical chemistry methods
amzamz
1
130
Other Decks in Research
See All in Research
SSII2025 [SS2] 横浜DeNAベイスターズの躍進を支えたAIプロダクト
ssii
PRO
7
4k
AIグラフィックデザインの進化:断片から統合(One Piece)へ / From Fragment to One Piece: A Survey on AI-Driven Graphic Design
shunk031
0
440
一人称視点映像解析の最先端(MIRU2025 チュートリアル)
takumayagi
6
3.5k
Submeter-level land cover mapping of Japan
satai
3
290
近似動的計画入門
mickey_kubo
4
1k
2025/7/5 応用音響研究会招待講演@北海道大学
takuma_okamoto
1
180
NLP Colloquium
junokim
1
200
Minimax and Bayes Optimal Best-arm Identification: Adaptive Experimental Design for Treatment Choice
masakat0
0
170
[論文紹介] Intuitive Fine-Tuning
ryou0634
0
110
Vision and LanguageからのEmbodied AIとAI for Science
yushiku
PRO
1
530
単施設でできる臨床研究の考え方
shuntaros
0
2.7k
A scalable, annual aboveground biomass product for monitoring carbon impacts of ecosystem restoration projects
satai
4
240
Featured
See All Featured
Save Time (by Creating Custom Rails Generators)
garrettdimon
PRO
32
1.6k
The Art of Programming - Codeland 2020
erikaheidi
56
13k
Measuring & Analyzing Core Web Vitals
bluesmoon
9
580
The Power of CSS Pseudo Elements
geoffreycrofte
77
6k
Code Reviewing Like a Champion
maltzj
525
40k
Speed Design
sergeychernyshev
32
1.1k
Building a Modern Day E-commerce SEO Strategy
aleyda
43
7.6k
Balancing Empowerment & Direction
lara
3
620
Exploring the Power of Turbo Streams & Action Cable | RailsConf2023
kevinliebholz
34
6k
Thoughts on Productivity
jonyablonski
70
4.8k
Fantastic passwords and where to find them - at NoRuKo
philnash
52
3.4k
Why Our Code Smells
bkeepers
PRO
339
57k
Transcript
Living in the Year 2020 ???
predictions very dangerous non-scientific as good as extrapolations
Example: Club of Rome vs. common sense
how to tackle the world population problem ? exponential
growth since WW2 keep biomass constant miniaturize human body size
extrapolation world population 0 20'000'000'000 40'000'000'000 60'000'000'000 80'000'000'000 100'000'000'000 120'000'000'000
140'000'000'000 160'000'000'000 180'000'000'000 200'000'000'000 1950 2000 2050 2100 2150 2200 year
miniaturizing humans body length 0 0.2 0.4 0.6 0.8 1
1.2 1.4 1.6 1.8 2 1950 2000 2050 2100 2150 2200 year
what is this now? nonsense? real possibility?
conclusions for our own research?
micro system technology for the life sciences a few thoughts
Andreas Manz, London
a micro system: what is it? microfabricated device for handling
of molecules and cells engineering a small space
micro chips
bioreactor
biochips, DNA array
on-line phosphate analyser
double stranded DNA separation
why? improved performance handling of small volumes / objects intellectual
property mass fabrication
volume of 1µL 1nL 1pL (1mm)3 (100µm)3 (10µm)3 600,000,000 600,000
600 25 / cm2 2500 / cm2 250 ,000/ cm2 17 min 10s 100ms 1.5 /min / cm2 250 /s / cm2 2,500,000 /s / cm2 # molecules (1nM solution) # volumes In array diffusion time # reactions (diffusion controlled) is a cube of
history 1979 gas chromatograph, Stanford USA 1980´s titration, Twente NL
1980´s blood gas analyzer, Sendai J 1990´s capillary electrophoresis, Basel CH 1990´s polymerase chain reaction, Livermore USA since 1995 exponential growth 2001 no turning point yet
activity today (absolute) 1. USA 2. Japan 3. Great Britain
4. Sweden 5. Switzerland 6. Korea
activity today (per capita) 1. Switzerland 2. Sweden 3. Denmark
4. Netherlands 5. USA 6. Ireland 7. Taiwan 8. Japan 9. Great Britain 10.Korea 11.Canada 12.Singapore 13.Finland
potential applications pharmaceutical industry $$$ chemical industry $$ instrument manufacturers
$$ clinical diagnostics $ environmental 0 ... more
predictions? micro system technology Pressure, acceleration, light, ink jets
market proportional to population saturated already less than 2x until 2020 no new parameters analyzed
None
None
None
predictions? MST for life sciences DNA, proteins, cells, metabolism
information needs are exploding right now just at the beginning, new parameters information density 1,000,000-times until 2020 new technology needed
products today vs. future
stock market Affymetrix 1’255’000’000 US$ Caliper Technologies 400’000’000
US$ Evotec Biosystems 474’000’000 US$ surprisingly small number of companies, still
last century was the century of physics / engineering will
this century be the century of biology ?
None
None