Upgrade to Pro
— share decks privately, control downloads, hide ads and more …
Speaker Deck
Features
Speaker Deck
PRO
Sign in
Sign up for free
Search
Search
living in the year 2020
Search
andreas manz
June 25, 2001
Research
2
55
living in the year 2020
... short talk given in Berlin. Hotel Adlon, June 25-26, 2001.
andreas manz
June 25, 2001
Tweet
Share
More Decks by andreas manz
See All by andreas manz
biomimetics
amzamz
0
18
Human Document Project
amzamz
0
190
microfluidics vs. self-assembly
amzamz
0
230
Human Document Project - introduction, goals & a small project
amzamz
0
300
microfluidics & miniaturization for clinical diagnostics
amzamz
0
210
Human Document Project - introduction, goals & myself
amzamz
0
110
chip-based microfluidic methods for analytical chemistry
amzamz
0
110
on nanofluidics and why it is so great
amzamz
0
75
chip technology, nanoliters and picoliters - miniaturization of (bio)analytical chemistry methods
amzamz
1
100
Other Decks in Research
See All in Research
DroidKaigi CfP分析
yukihiromori
0
110
1on1ガイドへの想い(chachaki編)
chachakix
0
150
機械学習と数理最適化の融合-文脈付き確率的最短路を例として-
mickey_kubo
2
670
-SSII技術マップを通して見る過去・現在,そして未来-
hf149
1
490
SSII2024 [SS1] 拡散モデルの今 〜 2024年の研究動向 〜
ssii
PRO
2
1.9k
点群処理の基礎: 平面の検出と、その上下の点の取り出しについて
kentaitakura
0
320
高精度、高効率アナログCompute-in-Memory回路に向けて
kentaroy47
2
110
Conducting AI Research on High-Performance Computing (HPC) Systems
yoshipon
2
460
ヘルプデスクの事例で学ぶAIエージェント
masatoto
11
4.5k
Harnessing the Power of Vicinity-Informed Analysis for Classification under Covariate Shift
nanofi
3
230
単語埋め込みを用いた日本語オノマトペにおける有声・無声子音の対立による音象徴の分析
shunnosukemotomura
0
390
SSII2024 [PD] 30周年記念特別企画SSII 技術マップ / LLMサーベイ
ssii
PRO
0
630
Featured
See All Featured
The Cult of Friendly URLs
andyhume
75
5.9k
YesSQL, Process and Tooling at Scale
rocio
166
14k
Docker and Python
trallard
37
2.9k
Optimising Largest Contentful Paint
csswizardry
18
2.6k
Six Lessons from altMBA
skipperchong
24
3.2k
Statistics for Hackers
jakevdp
792
220k
[RailsConf 2023 Opening Keynote] The Magic of Rails
eileencodes
17
8.7k
Fontdeck: Realign not Redesign
paulrobertlloyd
79
5.1k
Automating Front-end Workflow
addyosmani
1362
200k
Creatively Recalculating Your Daily Design Routine
revolveconf
214
11k
The Success of Rails: Ensuring Growth for the Next 100 Years
eileencodes
35
6.3k
Web development in the modern age
philhawksworth
203
10k
Transcript
Living in the Year 2020 ???
predictions very dangerous non-scientific as good as extrapolations
Example: Club of Rome vs. common sense
how to tackle the world population problem ? exponential
growth since WW2 keep biomass constant miniaturize human body size
extrapolation world population 0 20'000'000'000 40'000'000'000 60'000'000'000 80'000'000'000 100'000'000'000 120'000'000'000
140'000'000'000 160'000'000'000 180'000'000'000 200'000'000'000 1950 2000 2050 2100 2150 2200 year
miniaturizing humans body length 0 0.2 0.4 0.6 0.8 1
1.2 1.4 1.6 1.8 2 1950 2000 2050 2100 2150 2200 year
what is this now? nonsense? real possibility?
conclusions for our own research?
micro system technology for the life sciences a few thoughts
Andreas Manz, London
a micro system: what is it? microfabricated device for handling
of molecules and cells engineering a small space
micro chips
bioreactor
biochips, DNA array
on-line phosphate analyser
double stranded DNA separation
why? improved performance handling of small volumes / objects intellectual
property mass fabrication
volume of 1µL 1nL 1pL (1mm)3 (100µm)3 (10µm)3 600,000,000 600,000
600 25 / cm2 2500 / cm2 250 ,000/ cm2 17 min 10s 100ms 1.5 /min / cm2 250 /s / cm2 2,500,000 /s / cm2 # molecules (1nM solution) # volumes In array diffusion time # reactions (diffusion controlled) is a cube of
history 1979 gas chromatograph, Stanford USA 1980´s titration, Twente NL
1980´s blood gas analyzer, Sendai J 1990´s capillary electrophoresis, Basel CH 1990´s polymerase chain reaction, Livermore USA since 1995 exponential growth 2001 no turning point yet
activity today (absolute) 1. USA 2. Japan 3. Great Britain
4. Sweden 5. Switzerland 6. Korea
activity today (per capita) 1. Switzerland 2. Sweden 3. Denmark
4. Netherlands 5. USA 6. Ireland 7. Taiwan 8. Japan 9. Great Britain 10.Korea 11.Canada 12.Singapore 13.Finland
potential applications pharmaceutical industry $$$ chemical industry $$ instrument manufacturers
$$ clinical diagnostics $ environmental 0 ... more
predictions? micro system technology Pressure, acceleration, light, ink jets
market proportional to population saturated already less than 2x until 2020 no new parameters analyzed
None
None
None
predictions? MST for life sciences DNA, proteins, cells, metabolism
information needs are exploding right now just at the beginning, new parameters information density 1,000,000-times until 2020 new technology needed
products today vs. future
stock market Affymetrix 1’255’000’000 US$ Caliper Technologies 400’000’000
US$ Evotec Biosystems 474’000’000 US$ surprisingly small number of companies, still
last century was the century of physics / engineering will
this century be the century of biology ?
None
None