Upgrade to Pro
— share decks privately, control downloads, hide ads and more …
Speaker Deck
Features
Speaker Deck
PRO
Sign in
Sign up for free
Search
Search
living in the year 2020
Search
andreas manz
June 25, 2001
Research
2
58
living in the year 2020
... short talk given in Berlin. Hotel Adlon, June 25-26, 2001.
andreas manz
June 25, 2001
Tweet
Share
More Decks by andreas manz
See All by andreas manz
biomimetics
amzamz
0
20
Human Document Project
amzamz
0
200
microfluidics vs. self-assembly
amzamz
0
240
Human Document Project - introduction, goals & a small project
amzamz
0
320
microfluidics & miniaturization for clinical diagnostics
amzamz
0
230
Human Document Project - introduction, goals & myself
amzamz
0
120
chip-based microfluidic methods for analytical chemistry
amzamz
0
110
on nanofluidics and why it is so great
amzamz
0
79
chip technology, nanoliters and picoliters - miniaturization of (bio)analytical chemistry methods
amzamz
1
110
Other Decks in Research
See All in Research
MetricSifter:クラウドアプリケーションにおける故障箇所特定の効率化のための多変量時系列データの特徴量削減 / FIT 2024
yuukit
2
120
Leveraging LLMs for Unsupervised Dense Retriever Ranking (SIGIR 2024)
kampersanda
2
200
20240820: Minimum Bayes Risk Decoding for High-Quality Text Generation Beyond High-Probability Text
de9uch1
0
120
機械学習でヒトの行動を変える
hiromu1996
1
310
Weekly AI Agents News!
masatoto
25
24k
言語処理学会30周年記念事業留学支援交流会@YANS2024:「学生のための短期留学」
a1da4
1
240
129 2 th
0325
0
240
Geospecific View Generation - Geometry-Context Aware High-resolution Ground View Inference from Satellite Views
satai
1
100
VisFocus: Prompt-Guided Vision Encoders for OCR-Free Dense Document Understanding
sansan_randd
1
250
Global Evidence Summit (GES) 参加報告
daimoriwaki
0
150
文献紹介:A Multidimensional Framework for Evaluating Lexical Semantic Change with Social Science Applications
a1da4
1
220
Active Adaptive Experimental Design for Treatment Effect Estimation with Covariate Choices
masakat0
0
220
Featured
See All Featured
What’s in a name? Adding method to the madness
productmarketing
PRO
22
3.1k
The Myth of the Modular Monolith - Day 2 Keynote - Rails World 2024
eileencodes
16
2.1k
Typedesign – Prime Four
hannesfritz
40
2.4k
Optimising Largest Contentful Paint
csswizardry
33
2.9k
Code Review Best Practice
trishagee
64
17k
GraphQLの誤解/rethinking-graphql
sonatard
67
10k
The Language of Interfaces
destraynor
154
24k
Making the Leap to Tech Lead
cromwellryan
133
8.9k
GitHub's CSS Performance
jonrohan
1030
460k
Raft: Consensus for Rubyists
vanstee
136
6.6k
How to Ace a Technical Interview
jacobian
276
23k
The MySQL Ecosystem @ GitHub 2015
samlambert
250
12k
Transcript
Living in the Year 2020 ???
predictions very dangerous non-scientific as good as extrapolations
Example: Club of Rome vs. common sense
how to tackle the world population problem ? exponential
growth since WW2 keep biomass constant miniaturize human body size
extrapolation world population 0 20'000'000'000 40'000'000'000 60'000'000'000 80'000'000'000 100'000'000'000 120'000'000'000
140'000'000'000 160'000'000'000 180'000'000'000 200'000'000'000 1950 2000 2050 2100 2150 2200 year
miniaturizing humans body length 0 0.2 0.4 0.6 0.8 1
1.2 1.4 1.6 1.8 2 1950 2000 2050 2100 2150 2200 year
what is this now? nonsense? real possibility?
conclusions for our own research?
micro system technology for the life sciences a few thoughts
Andreas Manz, London
a micro system: what is it? microfabricated device for handling
of molecules and cells engineering a small space
micro chips
bioreactor
biochips, DNA array
on-line phosphate analyser
double stranded DNA separation
why? improved performance handling of small volumes / objects intellectual
property mass fabrication
volume of 1µL 1nL 1pL (1mm)3 (100µm)3 (10µm)3 600,000,000 600,000
600 25 / cm2 2500 / cm2 250 ,000/ cm2 17 min 10s 100ms 1.5 /min / cm2 250 /s / cm2 2,500,000 /s / cm2 # molecules (1nM solution) # volumes In array diffusion time # reactions (diffusion controlled) is a cube of
history 1979 gas chromatograph, Stanford USA 1980´s titration, Twente NL
1980´s blood gas analyzer, Sendai J 1990´s capillary electrophoresis, Basel CH 1990´s polymerase chain reaction, Livermore USA since 1995 exponential growth 2001 no turning point yet
activity today (absolute) 1. USA 2. Japan 3. Great Britain
4. Sweden 5. Switzerland 6. Korea
activity today (per capita) 1. Switzerland 2. Sweden 3. Denmark
4. Netherlands 5. USA 6. Ireland 7. Taiwan 8. Japan 9. Great Britain 10.Korea 11.Canada 12.Singapore 13.Finland
potential applications pharmaceutical industry $$$ chemical industry $$ instrument manufacturers
$$ clinical diagnostics $ environmental 0 ... more
predictions? micro system technology Pressure, acceleration, light, ink jets
market proportional to population saturated already less than 2x until 2020 no new parameters analyzed
None
None
None
predictions? MST for life sciences DNA, proteins, cells, metabolism
information needs are exploding right now just at the beginning, new parameters information density 1,000,000-times until 2020 new technology needed
products today vs. future
stock market Affymetrix 1’255’000’000 US$ Caliper Technologies 400’000’000
US$ Evotec Biosystems 474’000’000 US$ surprisingly small number of companies, still
last century was the century of physics / engineering will
this century be the century of biology ?
None
None